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James Frahill, who is a Research Analyst at the Pfizer Process Development Centre (Cork, Republic of Ireland), spoke to Bethany Degg of The Column about the role of the chromatographer in the pharmaceutical process development group at Pfizer.

This article describes the advantages of miniaturizing laboratory instruments, as well as the challenges to adapt to and overcome

The International Symposium on Capillary Chromatography (ISCC) and GCxGC Symposium combined conference provides an excellent combination of high impact, cutting edge science, and a great social program in an interesting venue. Kevin Schug shares his thoughts about innovations in gas chromatography presented at this year's conference in Riva del Garda, Italy.

Profiling impurities in MDMA (also known as ecstasy) is essential to forensic science as different profiles can provide clues about the source. Two researchers from Michigan State University (Michigan, USA) investigated the effect of liquid–liquid extraction (LLE), headspace solid-phase microextraction (HS–SPME), and different gas chromatography temperature programmes highlighting the need for standardized procedures.

Dried blood spot (DBS) sampling and high performance liquid chromatography coupled to high-resolution tandem mass spectrometry (HPLC–MS) has been demonstrated in the routine testing of athletes for anabolic steroid esters.

A new method for the purification of adenovirus serotype 5 (Ad5) by two-column, size-exclusion simulated countercurrent chromatography (SEC) has been published in the Journal of Chromatography A.

Click here to view the complete E-Separation Solutions newsletter from June 19, 2014.

Researchers at the Universite de Montreal in Canada have developed and validated a new liquid chromatography tandem mass spectrometry (LC–MS–MS) method to identify compounds present in suspected counterfeit or even adulterated erectile dysfunction drugs. According to the study published in the Journal of Chromatography A, the method has now been introduced to the Inspectorate Laboratory Programme at Health Canada (Canada).

This webcast will begin on Wednesday, July 23, 2014 at 2:00 PM EDT.

Click the title above to open The Column June 19, 2014 Europe & Asia issue, Volume 10, Number 11, in an interactive PDF format.

This Tuesday morning session will be presided over by Alison Danell of East Carolina University, and it will be held at 8:30?10:30 a.m. in Exhibit Hall AB.

The June 18 Wednesday morning session "The Triple Quadrupole: 35 Years of Evolution and Application to Celebrate Chris Enke's 80th Birthday" starts at 8:30 a.m. in Room 309-301. R. Graham Cooks, of Purdue University (West Lafayette, Indiana), will preside.

Today's workshops cover a variety of topics, including protein analysis, -omics, data analysis, a few specific areas of application, and career development.

Today?s plenary is the Biemann Medal Lecture, which will be given by Lingjun Li of the University of Wisconsin-Madison. Li is awarded the 2014 Biemann Medal for the number and depth of her contributions in the field of mass spectrometric study of neuropeptides and functional peptidomics.

Among the Tuesday afternoon oral sessions taking place on June 17 between 2:30 p.m. and 4:30 p.m. in Room 314-317 is ?Fundamentals of Peptide Fragmentation.? Yu Xia, of Purdue University (West Lafayette, Indiana), will preside.

This Wednesday afternoon session will be presided over by Demian Ifa of York University and will be held at 2:30–4:30 p.m. in Room 307-308.

This Wednesday morning session (WOA) will take place in Exhibit Hall AB from 8:30–10:30 a.m. Mark Lowenthall of the National Institute of Standards and Technology (NIST) will preside.

This Tuesday afternoon session (TOB) will take place from 2:30?4:30 p.m. in room 307-308. The session will be presided over by Bryan Fonslow of Scripps Research Institute.

The CHROMacademy technical team was recently posed with the question of the causes of baseline drift in gradient HPLC.

Chromatography troubleshooting tips from ChromAcademy.

Click here to view the complete E-Separation Solutions newsletter from June 12, 2014.

When developing a separation, some fundamental choices need to be made on how we might achieve the separation we require - primarily the mode of chromatography used and the way in which we intend to control and optimise the retention and separation (selectivity) of analyte components.

This Monday afternoon session, MOC, will be presided over by Gert Von Helden of Fritz-Haber University. The session will run from 2:30?4:30 p.m. in room 309-310.

Multi-detection GPC/SEC is described and new data showing how the technique is being used to determine the impact of sterilization on medical grade poly(L-lactide) is presented.

This Monday morning session will be presided over by Patrick Limbach of the University of Cincinnati and will be held at 8:30?10:30 a.m. in Room 307-308.

A new study in the journal Heart suggests that high performance liquid chromatography tandem mass spectrometry (HPLC?MS?MS) can be performed as a standard screening tool to identify patients who do not take the anti-hypertensive medications as prescribed by their doctor.1

GPC/SEC can be performed for samples that range from a few hundred to several million daltons in molar mass. It can often require more skill to analyze high molar mass samples in the molar mass range of several million dalton. This article explains more.

The use of high temperature adsorption liquid chromatography for the characterization of polyolefins is detailed.