All News

Immunoaffinity column sample clean-up and HPLC post-column photochemical derivatization with fluorescence detection to analyze sflatoxins B1,B2, G1, and G2.

Spring Scream is one of the largest music festivals held in Taiwan, and is reported to be associated with drug abuse and addiction.

A new study published in the Journal of Chromatography A presents a sensitive method for the quantification of apidaecins, a type of antimicrobial peptide that play an important role the immune response of honey bees to pathogens. The method was developed using reversed-phase nanoliquid chromatography coupled with high resolution mass spectrometry (LC–MS) to determine apidaecins in hemolymph or body parts from individual honey bees.

Click the title above to open The Column January 08, 2015 Europe & Asia issue, Volume 11, Number 1, in an interactive PDF format.

Click the title above to open The Column January 08, 2015 North American issue, Volume 11, Number 1, in an interactive PDF format.

Incognito discusses how investigating negative data can lead you to an unexpected positive result.

SFC was evaluated as an alternative to HPLC for the enantiomeric separation of primary amines on a cyclofructan-based CSP.

A snapshot of what’s on offer for chromatographers at Pittcon 2015.

Have a problem with your LC? Maybe applying a little DDT may help.

The fundamentals and applications of pyrolysis-G

Various analytical approaches and instrumentation for low?molecular-weight (MW), noncovalent, aggregates of proteins are discussed.

ISCC and GCXGC 2015

A guide to HPLC detector selection.

The use of a mass spectrometer in quantitative analysis exploits its exquisite selectivity and sensitivity as a detector, allowing a signal to be ascribed to a particular chemical entity with high certainty, even when present in a sample at a low concentration.

On October 21, 2014, University of Tennessee Distinguished Scientist Georges Andre Guiochon succumbed to neuromuscular failure caused by post-polio syndrome. Here, we pay tribute to his remarkable career and life.

Click the title above to open the LCGC Europe January 2015 regular issue, Vol 28, No 1, in an interactive PDF format.

Click the title above to open the LCGC North America January 2015 regular issue, Vol 33 No 1, in an interactive PDF format.

In this issue – I hope to outline some 'small bolts' that are commonly ignored in everyday chromatography and mass spectrometry - instrument settings that I have to come call 'lock and leave' parameters. We can generate data without changing them or paying them any attention, but how much better could our data be if we bothered to optimise them.

Büchi Expands into Malaysia and Singapore

The Kendrick mass defect combined with liquid chromatography quadrupole time-of-flight mass spectrometry (LC–qTOF-MS) can offer a variety of benefits to analysts investigating groundwater contamination. LCGC spoke to Thomas Borch from Colorado State University in Colorado, USA, about his work in this area to find out more.

The biopharmaceutical industry continues to focus on the development of biotherapeutic monoclonal antibody (mAbs) drugs. In this article, the compatibility of SEC coupled with HRAM–MS for the analysis of mAbs is demonstrated.

In this article, the application of silica monoliths with bimodal pore structure (macro and mesopores) is described for the chromatographic analysis of biomolecules including peptides, proteins, and antibodies.

How to transfer a chromatogram into the molar mass distribution.

Click the title above to open The Column December 15, 2014 North American issue, Volume 10, Number 22, in an interactive PDF format.

Click the title above to open The Column December 15, 2014 Europe & Asia issue, Volume 10, Number 22, in an interactive PDF format.