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"Dragon's Blood"(DB) has become increasingly popular in Europe and the USA this year. Marketed as an anti-ageing compound within cosmetics, DB is a deep red resin secreted from the fruit of the dragon tree species, Daemonorops draco. Scientists in China 2 believe they have identified two novel biomarkers that could be used in the QC of DB.

Jenny Button, Product Specialist at LGC Standards, UK, discusses some commonly reported errors in the use of reference materials and how they can be avoided.

John Hinshaw offers his insights into how the current helium shortage will affect gas chromatographers and answers some concerns of The Column readers selected from the CHROMacademy Forum.

Traditionally, measuring the mobility of proteins and nanoparticles has been a challenging task. An effective measurement method traditionally used is phase analysis light scattering (PALS), a technique based on interfering laser light scattered from a sample solution. However, it has been associated with two important shortcomings. Massively Parallel Phase Analysis Light Scattering (MP-PALS) has emerged as a viable alternative to the conventional PALS method.

Antibiotics are used frequently and there has been a corresponding growth in antibiotic-resistant bacterial strains, such as MRSA (multi resistant strain antibiotics). This resistance is placing pressure on healthcare systems worldwide with numerous government agencies, including the World Health Organization (WHO), campaigning to reduce the use of antibiotics. There is now an emerging research focus on the development of plant-based anti-microbial agents that could be used for non-medicinal purposes; specifically of interest is the use of antimicrobials in the preservation of foodstuffs.

John Hinshaw answers more LCGC readers’ concerns sent to the CHROMacademy forum following the recent CHROMacademy webinar on the helium shortage.

Series: Increasing the Scope of your Analytical Toolbox with UltraPerformance Convergence Chromatography (UPC2) - Episode 2

Waters EU - USP Method Transfer of Donepezil Tablets

Phenomenex (California, USA) has announced a partnership with the Feed my Starving Children (FMSC) (Minnesota, USA) organization to hand-pack 150,000 meals on the 16th and 17th of November for dispatch to developing countries

Agilent (California, USA) has announced the formation of a partnership with PREMIER Biosoft (California, USA). The partnership aims to aid the advancement of lipidomics research, by supporting integration of their respective software platforms allowing combination of data generation and processing. It is hoped that this will allow the mapping of complex lipidomic networks, advancing knowledge of lipid metabolism and diseases associated.

The authors characterized 12 SFC achiral stationary phases with 60 compounds from four chemical classes to establish guidelines for th rational selection of the optimum stationary phase for separations.

This is an update to a 2003 article with information about new developments in SPME.

Application Note

How can we tell if an LC method is working properly?

HPLC Analysis of Azide in Drug Substances

Click here to view the complete E-Separation Solutions newsletter from November 1, 2012.

The authors explore some basic thermodynamic relationships.

LCE media kit v13

LCE media kit v14

A simple and practical assay for azide using chemical derivatization and high performance liquid chromatography.

We explain the working principles of the most popular of all mass analyzing devices.

Written procedures used by trained staff are the basis for all quality systems but there are many ways of writing a procedure. Are you getting it write?

An excerpt from LCGC's e-learning tutorial on quadrupole mass analysers at CHROMacademy.com

In the 1960s, high performance liquid chromatography (HPLC) was in its infancy and Phyllis Brown was a pioneer at the forefront of the technique.

HPLC 2013

Click the title above to open the LCGC Asia Pacific November 2012 regular issue, Vol 15, No 4, in an interactive PDF format.

Click the title above to open the LCGC North America November 2012 regular issue, Vol 30 No 11, in an interactive PDF format.

The HPLC 2012 conference was abuzz with talk of "slip flow" following the talk given by Mary Wirth of Purdue University about her groundbreaking work involving protein column efficiency. In this interview, Wirth explains how “slip flow†works and what this discovery can contribute to the application of LC-MS to disease research.