All News

Chiral Separations

Chiral has long been one of the most important techniques in separation science. Joining us for this discussion are Martin Vollmer of Agilent Technologies and Elena Eksteen of Chiral Technologies.

58th ASMS Conference Review

LCGC reviews some of the highlights and award recipients from this year's ASMS conference, held May 23-27, 2010, in Salt Lake City, Utah.

Accelerating metabolic research

Agilent Technologies and Stemina Biomarker Discovery have announced that Agilent will be providing a liquid chromatography system and quadrupole time-of-flight mass spectrometer to accelerate Stemina's metobolomic research.

Rapid analysis of polycyclic aromatic hydrocarbons

A rapid gradient HPLC method for simultaneous determination of 16 PAH according to EPA 610 method is presented. A baseline resolution for all 16 target analytes in less than 2.50 minutes could be achieved by using a KNAUER BlueOrchid PAH 50 x 2 mm column.

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Underwater asphalt volcanoes

Ten miles off the Californian coastline, at the bottom of the Santa Barbara channel, domes rise from the Pacific Ocean floor. A paper published on-line in the journal Nature Geoscience identified these as a series of unusual underwater volcanoes.

Matrix Elimination — In-line Removal of Chloride using InGuard Ag and Na Cartridges

ByRosanne Slingsby,Rida Al-Horr,Bernard G. Sheldon

In ion chromatography, the presence of a large amount of matrix ions makes quantification of the target ions difficult. Selective removal of matrix ions - matrix elimination - can be performed by treating a sample with a solid-phase extractant. Halides can be removed by precipitation with silver, which is present as a counterion in a cation-exchange resin. A subsequent treatment with a cation-trapping column removes residual dissolved silver ions.

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Call for Application Notes

LCGC is planning to publish the next issue of The Application Notebook special supplement in September. The publication will include vendor application notes that describe techniques and applications of all forms of chromatography and capillary electrophoresis that are of immediate interest to users in industry, academia, and government. If your company is interested in participating in these special supplements, contact:

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Planning a Busy Summer at LCGC

ByMichael J. Tessalone

Traditionally, summer is a time when the worlds of lab research and business slow down to a large extent. If you work in academia, chances are many of your students have returned home for the summer and the teaching load has been reduce, while those of you working in private industry and research labs may see coworkers taking long-anticipated (and well-deserved) vacations.

Glycan Database

Ireland?s National Institute for Bioprocessing Research and Training (NIBRT) and Waters have announced a collaboration that will create the first database for glycan analysis by UPLC.

Determination of molecular weight distribution of polyacrylonitrile

A separation based on molecular size using GPC with organic eluents was demonstrated, along with a simple sample preparation procedure. Since this GPC application uses DMF and a small amount of lithium bromide as mobile phase, it will work on a standard HPLC system without any modifications. The molecular weight ranges (Mw) of the polyacrylonitrile samples analyzed were found to be in the middle of the linear calibration range.

A stem cells' metabolome

By using a metabolomic approach, a group of researchers have described some key differences between stem cells and mature cells as well as metabolites associated with the transition between the two.