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Ion Exchange Analysis of Monoclonal Antibodies on Large Pore TSK-GEL BioAssist Columns-Tosoh Application Note

A research group from NRL Marine Biotoxins, Federal Institute for Risk Assessment (Berlin, Germany) developed a solid-phase extraction (SPE) method for the enrichment and clean-up of lipophilic marine biotoxins from various species of bivalve molluscs and processed shellfish products.

ACD/Labs (Toronto, Canada) announced the release of new software for target analysis of complicated LC?MS and GC?MS datasets, without the tedious and difficult manual interpretation.

Stability of TSK-GEL SuperSW3000 Columns for Analyzing Proteins by SEC-Tosoh Application Note

French scientists have developed a GC?MS method, combined with a triple partition extraction step to reduce the amounts of co-extracted fats, for the determination of pesticides in meat-based baby foods.

Researchers from the Tokyo Institute of Technology (Tokyo, Japan) used thin-layer chromatography (TLC) and high performance liquid chromatography in a study of structures on plant surfaces that provide resistance against herbivores.

Researchers from Univerité de Lyon (Lyon, France) have developed a chromatographic method for distinguishing 100% natural honey from adulterated or impure honey.

Thermo Fisher Scientific (San Jose, California) announced that it has been presented with the ACHEMA 2009 Innovation Award for the category of Laboratory and Analytical Techniques.

Purification of a 13-mer DNA Phosphorothioated Crude Deprotected Oligonucleotide by Strong Anion Exchange Chromatography Using TSKgel DNA- NPR- Tosoh Application Note

For those of you who have not yet had a chance to read Spectroscopy and LCGC?s "Homeland Security" supplement (www.spectroscopyonline.com), Tuesday morning's "Mass Spectrometry in Homeland Protection" session should provide a nice overview of the topic.

Complete Carbamate Testing Solution-Waters Application Note

Tuesday afternoon's session titled "LC?MS Assessment of Human Metabolism Compliance with "MIST" Guidance" plans to tackle the topic of the key challenges for drug development as a result of the FDA?s MIST guidance.

Rapid and Accurate Simultaneous Quantitation of Low Concentration Amphetamines and Metabolites from Urine using Strata?-X*-C and LC/MS/MS on Gemini C18 -Phenomenex Application Note

It's all in the perspective.

Optimization of Wash-Elution Conditions-Phenomenex Application Note

Acetonitrile Shortage-SIELC Technologies Application Note

Columnist Michael Balogh looks at the questions: Where are we now? What do the early MS innovators see as their legacy? And what can we expect in the future?

Welcome again, to Day 2 of ASMS 2009. We?re pleased to bring you our continued coverage from Philadelphia, Pennsylvania. ASMS is in full swing, and last night?s hospitality suites were as crowded as ever, as you might imagine. Tonight promises to be another crowded night at the Marriott, but before then, there is a whole day of mass spectrometry-related science.

Rising stars interview leading figures in the world of chromatography. Gert Desmet talks to John Knox.

The call for increased biofuel production will surely be closely followed by a need for improved methods of analysis. The six presentations in this Tuesday morning session will examine various roles of mass spectrometry in biofuels analysis and will cover topics such as biodiesel characterization, metaproteomic analysis of termite microbes relevant to biofuel development, and multiple reaction monitoring of biofuels systems metabolic pathways.

United States Pharmacopeia (USP) general chapter 1058 on analytical instrument qualification (AIQ) has finally become official and was released in August 2008 in the first supplement to the USP XXXI.1 This column reviews AIQ and discusses the impact it will have in the regulated chromatography laboratory.

Evaporation-free extraction (no drying down) is highly desirable because of its reduced cost and pollution, higher speed, and less possibility for contamination and conversion. Presented in this article are four types of evaporation-free extraction that are widely applicable. The first one is for the determination of didanosine over the range of 25.02–2502.00 ng/mL by injecting solid-phase extraction (SPE) eluate directly. The second is for the determination of betamethasone phosphate over the range of 2.51–250.60 ng/mL by injecting SPE eluate after pH adjustment. The third is for the determination of sumatriptan over the range of 0.99–99.40 ng/mL based upon SPE with high organic washing and low organic elution. The fourth is based upon automated dilution after protein precipitation for the determination of raloxifene-4'-glucuronide and raloxifene-6-glucuronide over the ranges of 2.02–202.40 ng/mL and 0.40–39.95 ng/mL, respectively.

A session dedicated to "Accurate Mass LC-MS Approaches for Characterization and Quantification of Drugs and Metabolites" will kick off the fourth day of the technical program on Tuesday at the 57th ASMS Conference in Philadelphia, Pennsylvania.

ALMSCO International announced it has made several significant enhancements to its ClearView chromatography/MS data reprocessing software, which is distributed exclusively by Markes.

Continuous Chromatographic Separation of Salt From Sugars- Orochem Application Note

Assistant Editor Megan Evans takes a look back at the annual ASMS Conference that was recently held in Philadelphia.

Rapid Analysis of Capsaicinoids-Hitachi Application Note

The historic city of Dresden, Germany will host HPLC 2009 - 34th International Symposium on High-Performance Liquid Phase Separations and Related Techniques. This symposium will be held in Dresden's International Congress Centre from 28 June–2 July 2009.