
A session dedicated to "Accurate Mass LC-MS Approaches for Characterization and Quantification of Drugs and Metabolites" will kick off the fourth day of the technical program on Tuesday at the 57th ASMS Conference in Philadelphia, Pennsylvania.

A session dedicated to "Accurate Mass LC-MS Approaches for Characterization and Quantification of Drugs and Metabolites" will kick off the fourth day of the technical program on Tuesday at the 57th ASMS Conference in Philadelphia, Pennsylvania.

ALMSCO International announced it has made several significant enhancements to its ClearView chromatography/MS data reprocessing software, which is distributed exclusively by Markes.

Continuous Chromatographic Separation of Salt From Sugars- Orochem Application Note

Assistant Editor Megan Evans takes a look back at the annual ASMS Conference that was recently held in Philadelphia.

Rapid Analysis of Capsaicinoids-Hitachi Application Note

The historic city of Dresden, Germany will host HPLC 2009 - 34th International Symposium on High-Performance Liquid Phase Separations and Related Techniques. This symposium will be held in Dresden's International Congress Centre from 28 June–2 July 2009.

Thermo Fisher Scientific has been presented with the ACHEMA 2009 Innovation Award for the category of Laboratory and Analytical Techniques. The PROCESS Innovation Award honours the most innovative technologies and equipment at ACHEMA, which this year had more than 4000 exhibitors.

Is the renewed interest in Green Chromatography marketing hype, or is the industry starting to take the topic seriously?

LGC Standards has opened its first office in Beijing, China, a milestone in the company's international development. The new office will enable the company to bring its range of laboratory quality products and services to the Chinese market and offer logistical and technical advice to Chinese laboratories in their local language.

The University of Oxford has recently been awarded a Wellcome Trust Technology Development Grant to work on the detection and characterization of nanoparticles in the early detection of human disease.

Japan's National Police Agency (NPA) has purchased 51 Thermo Scientific LXQ linear ion trap mass spectrometers and 27 of the company's Nicolet 6700 FTIR spectrometers with Continuµm microscopes.

A company's environmental management system, canine training, protein analysis to answer evolutionary questions and a community award are in the news this month.

The Optic 3 injector is a versatile tool for the Shimadzu GC and GC–MS product range. It features no discrimination and low thermal degradation of the sample.

The official opening session and Plenary Lecture featured a talk from Jerald L. Schnoor, of the University of Iowa, entitled, ?Biofuels and Global Climate Change.? This topic was especially fitting for the June conference as gas prices and temperatures are on the rise once again this summer.

After a day filled with registration and short courses, Willard W. Harrison kicked off a series of three lectures with his tutorial lecture on Sunday night at the 57th ASMS Conference held in Philadelphia, Pennsylvania.

A simple and generic strategy from Waters for metabolite identification studies that uses ACQUITY UPLC and a new, highly-sensitive hybrid quadrupole oa-TOF benchtop mass spectrometer: the Xevo QTOF-MS.

Elemental mass spectrometry mainly targets inorganic materials, determining elemental compositions of samples rather than providing structural information. This session will cover topics such as bioimaging of metals in brain tissue, the analysis of chemical warfare agent degradation products, and the separation and quantitation of antisense oligonucleotides.

Good morning, and welcome to this, the opening day of LCGC?s and Spectroscopy?s ASMS E-Show Dailies from Philadelphia, Pennsylvania. For the next three days, we will be covering all that is new and exciting at ASMS this year, from technical sessions to plenary lectures to the social networking that is a big part of any conference.

GPC is used to easily and reliably analyze the molecular mass distribution of industrially produced polyacrylnitrile in this application note. Polyacrylnitrile (PAN) is an important component of many industrial products including heavy-duty fibres, synthetic ropes, flame resistant plastics, and the versatile impact resistant ABS plastics. PAN is also commonly used to produce fabric for clothing manufacture since its addition creates a material that is warming, soft and crease-resistant. This application demonstrates a separation based on molecular size using GPC with organic eluents, along with a simple sample preparation procedure. Since this GPC application uses DMF and a small amount of lithium bromide as mobile phase, it will work on a standard HPLC system without any modifications.

The authors demonstrate the capacity to separate petroleum-derived molecules having the same nominal mass in the mobility dimension using IM-MS spectrometry.

The 57th ASMS Conference on Mass Spectrometry will be held at the Pennsylvania Convention Center, 1101 Arch Street, Philadelphia, Pennsylvania, from May 31 through June 4, 2009.

In an effort to reduce the number of potential drugs that fail during clinical development, drug companies are increasingly looking to human microdosing.

Joining us for this discussion are Dr. Peter Hoedl of PerkinElmer EcoAnalytix; Daniela Cavagnino from Thermo Fisher Scientific, Inc.; Sky Countryman of Phenomenex; and Mark Taylor and Rick Koeritz of Shimadzu Scientific Instruments, Inc.

MRM Quantification of Chitotriosidase in Human Plasma-Waters Application Note

Frost & Sullivan is pleased to present the 2009 Company of the Year Award in the drug discovery technologies market to Life Technologies. According to Frost & Sullivan, the company's size, product portfolio breadth, market segment leadership, and strong future potential set it apart from any competitor in the life science research tools industry.

Bruker Daltonics has announced an exclusive distribution agreement with Francisco Soria Melguizo at the 19th European Congress of Clinical Microbiology and Infectious Disease. Francisco Soria Melguizo will distribute Bruker Daltonics' matrix-assisted laser desorption/ionization (MALDI) Biotyper to laboratories in clinical microbiology and veterinary medicine in Spain.

High-Throughput Analysis of Metabolic Stability Incubations-Thermo Application Note

Absolute Quantitation of Targeted Endogenous Salivary Peptides-Thermo Application Note

Light scattering is one of the few absolute methods for the characterization of macromolecules and biopolymers. On-line light-scattering detectors are used in GPC/SEC systems to measure molar masses, the radius of gyration and to identify high molar mass content at low concentrations. There are several detectors available that differ in the provided light-scattering technique. It is necessary to select the correct technology for a specific application and to do this users need to know the basic principles.

The precise quantitation of protein expression levels can provide crucial insights into physiological processes in both healthy and diseased organisms. Protein dynamics ? changes in proteins over time ? characterize normal processes such as growth and development, and pathologic processes such as the development and progression of cancer. Protein dynamics can provide biomarkers for physiologic responses to pharmacotherapy.