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Researchers from Hiroshima University (Hiroshima, Japan), Hiroshima Prefectural Police Headquarters (Hiroshima), Tokai University School of Medicine (Kanagawa, Japan), and GL Sciences Inc. (Saitama, Japan) developed a spin column device packed with octadecyl silane-bonded monolithic silica for extracting amphetamines and methylenedioxyamphetamines from urine.

Thermo Fisher Scientific (San Jose, California) announced that a method that uses the company?s equipment for detecting melamine and cyanuric acid in food matrixes was described in the U.S. FDA?s Laboratory Information Bulletin Number 4396, May 2007.

Researchers from Universita degli Studi di Parma (Parma, Italy) used immunomagnetic beads to extract trace peanut allergen protein Ara h3/4 from breakfast cereals.

Waters Corporation (Milford, Massachusetts) has joined the BioIT Alliance, an initiative spearheaded by Microsoft Corporation (Redmond, Washington) that involves more than 80 pharmaceutical, biotech, laboratory instrument, and software companies working together to advance personalized medicine.

Scientists from Hoshi University (Tokyo, Japan) and the National Research Institute of Police Science (Chiba, Japan) employed stir-bar sorptive extraction (SBSE) and thermal desorption gas chromatography?mass spectrometry (GC?MS) for analyzing 5-chloro-2-(2,4-dichlorophenoxy)phenol, otherwise known as triclosan, in river water samples.

LCGC Europe eNews

Thermo Fisher Scientific showcased its comprehensive laboratory instrumentation and informatics solutions for food, beverage and agricultural applications at the 2008 Association of Analytical Communities (AOAC) annual meeting and exposition at the end of September...

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HCTultra ETD II

Bruker Daltonics announces ETD II, a next-generation ETD (electron transfer dissociation) module for its HCTultra™ high capacity ion traps.

LCGC Europe eNews

The Swedish National Food Administration in Uppsala and the Karolinska Institute in Stockholm have been looking at the potential toxicity of musks following their discovery in human milk, when mothers are breastfeeding...

E-Separation Solutions

The following question and answer were taken from LCGC Europe's "CE Currents" column (1). How should I approach method development? If possible request any details of sample stability, pKa, and solubility in different solvents and pH ranges. Information on solvents used in HPLC can also be useful.

E-Separation Solutions

Size exclusion chromatography (SEC) is a powerful tool for the characterization of molecules differing in size and molar mass. It is widely used and well known for the determination of molar mass distributions and molar mass averages. For membranes GPC/SEC is a useful characterization method as it can measure the membrane characteristic pore size distribution, average pore size and molecular cut-off significantly faster than other methods.

E-Separation Solutions

Transforming "standard" gradient HPLC systems into extremely fast gradient systems is readily achievable with proper application of chromatographic principles, particularly temperature control, combined with utilization of advanced HPLC columns. Bottom line: You don't have to buy a new LC to achieve ultra high quality and speed!

The Column: October 2008

The Column

Rapid Fatty Acid Fingerprinting in Microalgae by Gas Chromatography: Analytical Opportunities Lieve M. L. Laurens Tips and Tricks: GPC/SEC Understanding Positive and Negative Detector Signals Daniela Held and Peter Kilz Biodiesel Patterns Reflect Quality: Analysis According to DIN EN 14103 Margit Geissler Bringing Together GC and LC on an MS–TOF System Ralf Dunsbach and Ralf Ketterlinus News All the news for October 2008 Incognito Total Solutions - Really? This month Incognito asks how "total" are the solutions being offered by the "Total Solutions" providers! Market Trends and Analysis Market Profile: The Analytical and Life Science Instruments Industry Glenn Cudiamat Q&A Craig Dobbs from pharmaceutical business operations at Waters, reveals what the company can offer scientists involved in implementing PAT and why the company has launched a chromatography system dedicated to this market that offers real-time monitoring

LCGC North America

PerkinElmer, Inc. (Waltham, Massachusetts) announced an arrangement with the University of Texas M.D. Anderson Cancer Center (Houston, Texas) that will bring the company's Array Comparative Genomic Hybridization technique to the cancer center.

LCGC North America

Chromatide (Runcorn, Cheshire, UK) and Separation Product's Kromasil, a brand of Azko Nobel (Amsterdam, The Netherlands) have set up a research collaboration to develop and market silica-based HPLC media.

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LCGC Europe

Very short columns filled with 1.9 µm particles were evaluated for the ultra-fast analysis of pharmaceutical formulations. Local anæsthetic, mydriatic and anti-hypertensive agents were chosen as analytes and a method was developed and validated for each of these substances, according to ICH guidelines. Excellent quantitative performance was obtained using an optimized chromatographic system that reduces the importance of extra-column effects and cuts the analysis time to less than 15 s.

LCGC North America

Pittcon (Pittsburgh, Pennsylvania) announced that twelve sessions at Pittcon 2009 at McCormick Place South in Chicage, March 8-13, will be coprogrammed with the ACS Division of Analytical Chemistry (ACS-DAC).

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Microemulsion HPLC

LCGC Europe

Microemulsion liquid chromatography (MELC) is a recent development offering reduced sample preparation times for complex samples and generic separation conditions applicable to a wide range of solutes. This article introduces the concepts of MELC and discusses the possible benefits and future applications.

A research group from Yanbian University and the Key Laboratory of Organism Functional Factors of the Changbai Mountain (both Yanji City, Jilin Province, China) examined the effect of the vapor pressure of the extracting solvent on the enrichment factor in headspace liquid-phase microextraction.

Researchers from the Technical University of Denmark and (Lyngby, Denmark) and the Danish Meat Research Institute (Roskilde, Denmark) used a mixed-mode reversed phase?anion exchange cleanup method followed by LC-MS with electrospray ionization time-of-flight detection to analyze mycophenolic acid in dry-cured ham, fermented sausage, and liver pate.

Researchers Philip Marriott from the RMIT University (Melbourne, Australia), Warawut Tiyapongpattana, and Prapin Wilairat from the Mahidol University (Bangkok, Thailand) have developed a 2D GC with FID method for determining the composition of biofuels that extends to the C4-C24 esters. They reasoned that a 2D separation, based first on boiling point then on polarity, would provide better resolution of the components.

Researchers at Beijing Normal University and the Institute of Beijing Criminal Science and Technology (China) used ion pairing high performance liquid chromatography (HPLC) to analyze 12 black inks and six red inks from various manufacturers in a number of countries.