
Metrohm Application Note

Metrohm Application Note

Positron emission tomography (PET) is one of the most powerful noninvasive diagnostic tools for tracing organ functioning. Quality control of the short-lived radiopharmaceuticals is challenging, not at least because of the tough time limits, the radiation issue, and the near nanomole radiotracer quantities.

Risedronate, a pyridinyl bisphosphonate, is one of the most popular first-line drugs in the treatment of osteoporosis, Paget's disease, and other bone fragility conditions. In October 2010, the United States FDA approved a second-generation risedronate in a delayed-release formulation.


This article describes a 2D matrix elimination ion chromatography method to analyse samples containing high levels of matrix ions.

The presented ion chromatographic method is used for the simultaneous determination of HF, HNO3, H2SO4, short-chain organic acids and H2SiF6 in acidic texturing baths that are used in the wet chemical etching process of solar cell production.

A review of separations of chlorite, chlorate and bromate in water using ion chromatography and their determination.

A review of separations of chlorite, chlorate and bromate in water using ion chromatography and their determination.

Ion chromatography (IC) is a similar technique to HPLC except that the detector of choice is usually a conductivity detector.

Ion chromatography (IC) is a similar technique to HPLC except that the detector of choice is usually a conductivity detector. IC is well suited for the analysis of a variety of inorganic and organic anions and cations.

This article describes a straightforward ion chromatographic method that uses isocratic elution and pulsed amperometric detection (PAD) to sensitively determine water-soluble polyols and sugar alcohols as well as mono-, di- and oligosaccharides in essential and non-essential foodstuffs. While carbohydrate determination of most foodstuffs requires only minimal sample preparation such as dilution and filtration, samples with interfering matrices such as protein-containing dairy products have to be dialysed before injection.

This article describes a straightforward ion chromatographic method that uses isocratic elution and pulsed amperometric detection (PAD) to sensitively determine water-soluble polyols and sugar alcohols as well as mono-, di- and oligosaccharides in essential and nonessential foodstuffs.


Joining us for a discussion on ion chromatography this month are experts from Dionex, Metrohm and Merck.

Joining us for a discussion on ion chromatography this month are experts from Dionex, Metrohm and Merck.

Metrohm Application Note

The fully automated combustion ion chromatography (CIC) system presented here combines a highly efficient combustion system with the separation power of ion chromatography (IC). CIC allows for the simultaneous, speciated trace analysis of halide (F, Cl, Br and I) and sulphur compounds (as sulphate) from sub-ppm to percent levels in any nonaqueous sample matrix.

Methacholine chloride is a synthetic analogue of the neurotransmitter acetylcholine used to assess bronchial asthma of subjects in respiratory function labs and epidemiological field studies.

The basics of IC are reviewed and recent advances that may extend this technology to new applications are discussed.


The fully automated combustion ion chromatography (CIC) system presented here combines a highly efficient combustion system with the separation power of ion chromatography (IC).

Methacholine chloride is a synthetic analogue of the neurotransmitter acetylcholine used to assess bronchial asthma of subjects in respiratory function labs and epidemiological field studies (1).

This article considers some examples of uses of ion chromatography.

Separation of Chromium (III) and Chromium (VI) by Ion Chromatography - Dionex Apps Note

Organic acids are present in many media and play various crucial roles. Low molecular mass organic acids (LMMOAs) have been researched extensively in many areas, such as food chemistry, as these acids affect taste, shelf-life, and food safety (1–3); agriculture, ecosystems, and environmental science, as these acids act as key components in mechanisms that some plants use to cope with environmental stress (4) and fertilizer release (5); biotechnology, to better understand and optimize fermentation processes (6,7); and biomedical research (8–11). Recently, LMMOAs were found to have inhibitory effects on the bioconversion efficiencies of lignocelluloses to ethanol (12).