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Capillary Electrophoresis

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ChromAcademy

Corporate Profiles

Data Acquisition, Handling, and Archiving

Data Analysis, Statistics, and Chemometrics

Dietary Supplements Analysis

Environmental Analysis

Field-Flow Fractionation (FFF)

Food and Beverage Analysis

Forensics, Narcotics

From the Editor

GC–MS

Gas Chromatography (GC)

LCGC TV: Gas Chromatography

LCGC TV: Hyphenated Techniques

LCGC TV: Liquid Chromatography

LCGC TV: Sample Preparation

LC–MS

Liquid Chromatography (LC/HPLC)

Peer-Reviewed Articles

Pharmaceutical Analysis

Preparative-Scale Chromatography

Process Analytical Technology (PAT)

Quality Control/Quality Assurance (QA/QC)

Quality by Design (QbD)

Regulatory Standards, GLP and GMP Compliance

Sample Preparation

Size-Exclusion Chromatography (SEC)

Solid-Phase Extraction (SPE)

Supercritical Fluid Chromatography (SFC)

Supercritical Fluid Extraction (SFC)

The Next Generation

Thin Layer Chromatography

Trends

UHPLC

Web of Science

Ion Chromatography

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Best of the Week: HPLC 2025 Previews, Interviewing 2025 ASMS Award Winners, Biopharmaceuticals and Artificial Intelligence

By Aaron Acevedo

May 16th 2025

Here is some of the most popular content posted on LCGC International this week.

New device | Image Credit: © pressmaster - stock.adobe.com

Design of a 3D-Printed Needle-Plate Ion Source for High Field Asymmetric Waveform Ion Mobility Spectrometry

By Dongmei Li
Yuqiao Zhang

Peng Shang
Kaikun Zhong
Xiaoxia Du

May 13th 2025

A new paper presents the design of a needle-plate dielectric barrier discharge DBD ion source based on 3D printing for high field asymmetric-waveform ion-mobility spectrometry (FAIMS).

The laboratory scientist prepares samples for download to High-performance Liquid Chromatograph Mass Spectrometr. | Image Credit: © Sodel Vladyslav

Reversed-Phases for LC Deliberately Doped with Positive Charge: Tips and Tricks for Effective Use

By Kevin Crossley
Wesley W. Barnhart

Dwight R. Stoll
Imad A. Haidar Ahmad

May 13th 2025

In this month's edition of LC Troubleshooting, Dwight Stoll and his fellow researchers discuss both the benefits (improved peak shape/loading) and challenges (excessive interaction) associated with charge-doped reversed-phase (RP) columns for both analytical and preparative separations.

Shot of Dark Data Center With Multiple Rows of Fully Operational Server Racks. Modern Telecommunications, Cloud Computing, Artificial Intelligence, Database, Supercomputer. | Image Credit: © Gorodenkoff - stock.adobe.com

Evaluating the Accuracy of Mass Spectrometry Spectral Databases

By Aaron Acevedo

May 12th 2025

Mass spectrometry (MS) can be effective in identifying unknown compounds, though this can be complicated if spectra is outside of known databases. Researchers aimed to test MS databases using electron–ionization (EI)–MS.