
Agilent Technologies, Inc.
Articles by Agilent Technologies, Inc.




This selection poster will guide you to find the best preparative LC column for your analysis with tips and guidance for stationary phase, the purification workflow, instrument compatibility, and links to useful resources such as an LC Scaling Calculator.

Webinar Date/Time: Tue, Oct 7, 2025 11:30 AM EDT

Webinar Date/Time: Tuesday, September 30, 2025 8am PDT | 11am EDT | 4pm BST | 5pm CEST

As analytical methods like high-performance liquid chromatography (HPLC) evolve, it becomes increasingly complex for labs to balance performance, price, and support. This infographic, based on independent LCGC International surveys commissioned by Agilent Technologies, reveals evolving end-user preferences, top performance drivers, and brand rankings in reliability and cost-efficiency.

Forward-thinking labs can make smarter, more cost-effective decisions when investing in quality analytical liquid chromatography (LC) systems. This eBook, based on the findings from biannual surveys conducted by LCGC International in partnership with Agilent Technologies, uncovers the hidden costs behind instruments and shows how reliability, expert customer support, and long-term value can drive operational excellence. Ultimately, cutting-edge innovations, including ultra-high performance liquid chromatography (UHPLC), are redefining performance, speed, and scientific potential in the modern LC lab.

With growing concerns over PFAS in food, reliable detection methods are essential for safety and compliance. This e-book explores advanced techniques for analyzing PFAS in various food matrices.

As PFAS contamination spreads across the environment, advanced screening and characterization techniques are crucial for detection and risk assessment. This e-book explores cutting-edge analytical methods for identifying PFAS in environmental and biological samples.

Dan Spisak, Product Marketing Director at Agilent, discusses key advantages to the Infinity III LC series and its features – as well as the upgradeability of older systems.

This application note presents the development and validation of a multi-component method for the analysis of 21 PFAS compounds in chicken eggs.

Webinar Date/Time: Wednesday, April 2nd, 2025 Session 1: 8:00 AM PDT | 11:00 AM EDT | 4:00 PM BST Session 2: 11:00 AM PDT | 2:00 PM EDT Thursday, April 3rd, 2025 Session 3: 11:00 AM JST | 10:00 AM CST

This application note presents the development and validation of a multiresidue method for the analysis of PFAS in baby food.

This application note presents the development and validation of a multiresidue method for the analysis of PFAS residues in beef, tuna, and shrimp.

This application note presents the development and validation of a multiresidue method for the analysis of PFAS in fruits, vegetables, and juices.

The increasing demand for high-purity, regulatory-compliant guide RNA (gRNA) manufacturing in the CRISPR gene editing market underscores the need for advanced production capabilities.


This application note demonstrates the superior resolution and recovery of Agilent AdvanceBio SEC 500 Å columns when compared with competitor products for AAVs.

This app note describes a non ion-pairing reversed-phase LC/MS method for highly modified ASOs, DNA, sgRNA, and siRNA ranging from 14- to 103-mer oligonucleotides.

This application note demonstrates a liquid chromatography/quadrupole time-of-flight mass spectrometer (LC/Q-TOF MS) workflow for the identification and characterization of therapeutic peptides.


Webinar Date/Time: Wed, Jan 22, 2025 11:00 AM EST

Agilent and Scitara are collaborating not only to increase the efficiency of laboratory processes, but to enable customers to leverage the value of the data for various stakeholders. This paper will present an ecosystem designed to support enterprises in accelerating data workflows and improving data availability for researchers, lab analysts, and data scientists.

Advanced Column Selection and Method Optimization for Biomolecular Purification and Characterization
Webinar Dates/Times: Tuesday, December 10, 2024 7am PST | 10am EST | 3pm GMT | 4pm CET

Webinar Dates/Times: Tue, Dec 3, 2024 11:00 AM EST

Webinar Date/Time: Wed, Dec 11, 2024 11:00 AM EST

Oligonucleotides—therapeutic agents for difficult-to-treat diseases—rely on precise molecular weight confirmation to ensure quality during development. Experts from Agilent Technologies explore the challenges of liquid chromatography-mass spectrometry (LC/MS) analysis in oligonucleotide synthesis, as well as strategies for accurate deconvolution, method development, and optimal equipment selection.

Top-down fragmentation enables rapid characterization of phosphorylated proteins without extensive sample preparation and digestion. In this study, electron capture dissociation (ECD) was used to fragment proteoforms of the cell death-related protein, Bcl-xL. Using these methods, 85–90% sequence coverage was achieved for Bcl-xL proteoforms, allowing for effective localization of phosphorylation within minutes.

Enhanced antibody analysis using electron capture dissociation (ECD) allows for precise glycan localization in low-abundance glycopeptides. This study compares the fragmentation of trastuzumab tryptic digests using ECD and collision-induced dissociation (CID). While CID generates abundant glycan HexNAc ions at 204 m/z, ECD preserves the labile glycan group, enabling accurate site localization.
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