This application note describes the evaluated quantification performance of eight nitrosamine impurities using an Agilent 6495D triple quadrupole LC/MS (6495D LC/TQ) system coupled with an Agilent 1290 Infinity II bio LC system and Agilent APCI source.
Recently, attention has been drawn to the use of microdroplet reactions for antibody analysis. The NIST IgG1 mAb was used to optimize microdroplet reaction conditions on two reactions, IdeS cleavage and disulfide bond reduction, using the Agilent Jet Stream ESI source.
In this app note you will learn how to develop a highly specific, sensitive, and reproducible method for the quantitation of N-nitroso dabigatran etexilate impurity in dabigatran etexilate mesylate drug substance using an Agilent 6495C triple quadrupole LC/MS (LC/TQ) coupled to an Agilent 1290 Infinity II LC.
This application note presents an alternative method using time-of-flight liquid chromatography/mass spectrometry (TOF LC/MS) and hydrophilic interaction chromatography (HILIC) that enables accurate and repeatable analysis of diverse oligonucleotides without using ion-pairing reagents.
Webinar Date/Time: Tue, Jan 23, 2024 11:00 AM CET (5:00 AM EST)
Webinar Date/Time: Europe: Tuesday, January 16, 2024 at 7am PST | 10am EST | 4pm CET North America: Tuesday, January 16, 2024 at 11am PST | 2pm EST | 8pm CET Asia: Wednesday, January 17, 2024 at 8:30am IST | 11am CST | 12pm JST
Webinar Date/Time: Thu, Jan 18, 2024 2:00 PM EST
Webinar Date/Time: Wednesday, December 13th, 2023 at 11am EST | 8am PST | 4pm GMT | 5pm CET Wednesday, December 13th, 2023 at 2pm EST | 11am PST | 7pm GMT | 8pm CET Thursday, December 14th, 2023 at 11am CST | 12pm JST
Webinar Date/Time: Thursday, November 30, 2023 at 9am EST | 2pm GMT | 3pm CET Friday, December 1, 2023 at 2pm EST | 7pm GMT | 8pm CET
The study of Per- and Polyfluoroalkyl Substances (PFAS) is vital for understanding the impact of these persistent chemicals on our health and environment, as well as developing effective mitigation strategies:
Webinar Date/Time: Thu, Nov 9, 2023 2:00 PM EST
GPC/SEC-viscometry enables measurement of true molar masses for carrageenan and detects subtle differences between samples with similar molar mass distributions.
GPC/SEC-MALLS analysis of hyaluronic acid obtains absolute molar mass while conventional GPC/SEC with concentration detectors only provides apparent molar masses.
This technical overview discusses best handling practices for IVT mRNA and analysis with the Fragment Analyzer systems, including sample handling and quantification tips.
Discover how SEC can be used in biopolymer applications including bioconjugates, proteins, mAbs, mRNA1, viruses, extracellular vesicles, and liposomal nanoparticles.
This paper discusses sustainable solutions for size separation of macromolecules that align with the 12 principles of green chemistry.
Tips & Tricks designed to support GPC/SEC users in their daily work, providing comprehensive overviews on different aspects of this powerful technique.
Robust, reliable GPC/SEC analysis of saccharides and polysaccharides can occur with very high resolution using Agilent SUPREMA columns with 3 and 5 µm particles.
Explore Agilent's innovations—from advanced light scattering to versatile software solutions—shaping the landscape of GPC SEC for enhanced macromolecule insights
Webinar Date/Time: Thursday, September 14th, 2023 at 8am PDT | 11am EDT | 4pm BST | 5pm CEST Thursday, September 14th, 2023 at 11am PDT | 2pm EDT | 7pm BST | 8pm CEST Friday, September 15th, 2023 at 11am CST | 12pm JST
The new Revident LC/Q-TOF system is leveraged for the screening of pesticides in complex matrix utilizing data independent acquisition (DIA). Confident identification is made through a combination of high-resolution, extended dynamic range, stable accurate mass, and isotopic fidelity which can be quickly and easily analyzed via the customizable LC Screener Tool, simplifying the processing of complex screening data. Along with this screening capability, new automated software, Intelligent Reflex, uses the results and allows for the reinjection and targeted confirmation of questionable and/or identified residues. This reduces the amount of time from sample introduction to confident characterization.
Webinar Date/Time: Tue, Aug 15, 2023 11:00 AM EDT
