John Chasse

Researchers at the Cleveland Clinic, using liquid chromatography tandem mass spectrometry (LC-MS/MS), determined that xylitol may be a risk factor related to a major adverse cardiovascular event.

Researchers have evaluated the possibility of analyzing finger sweat through liquid chromatography-mass spectrometry (LC-MS) to ensure medication adherence and as a semi-quantitative tool in therapeutic drug management assessment and report positive results.

Kevin A. Schug of The University of Texas at Arlington and his team partnered with The Lummus Technology (Pasadena, TX) to develop a method of pyrolysis based on supercritical fluid chromatography (SFC) with ultraviolet (UV) detection. Schug spoke to us about the process and the paper that resulted from its development.

The NASA Perseverance Mars Rover and its spectrometer is once again fully functional after six months of not being operational.

In this “Equipment Roundup,” the editors of LCGC International feature new instruments from Sartorius and Shimadzu.

Researchers in Western Australia have used high-performance thin layer chromatography (HPTLC) to authenticate Jarrah flower nectar and honey.

Research published in Frontiers in Environmental Science, utilizing high-resolution mass spectrometry, reports that chemical substances from tire wear have found their way into the food chain.

In this equipment roundup, the editors of LCGC International highlight new instruments from Bruker and Shimadzu.

Maria Concheiro of John Jay College (New York City) spoke to LCGC International about her research identifying and quantifying pharmaceuticals and drugs of abuse in river water samples collected from the Hudson and East Rivers in New York City, as well as investigating the possible source of these micropollutants

The global chromatography food testing market is estimated to exhibit a compound annual growth rate (CAGR) of 6.27% during the forecast period of 2023-2031, states a recent market assessment report on the subject.

A recent study published investigates the chemoselective behavior and the interplay between enantiorecognition of organophosphorus pesticides and their metabolites under multimodal elution using liquid chromatography (LC).

A technique to measure total phenolic content (TPC) in vegetable oils through analysis of images captured by a cellphone may prove to be easier to utilize than the traditional methods of ultraviolet/visible (UV-vis) spectrophotometry, high-performance liquid chromatography (HPLC), and gas chromatography (GC).

The effects of simulated digestion on the formation of α-dicarbonyl compounds (α-DCs) in chocolates were assessed in a recent study with high-performance liquid chromatography (HPLC).

A recent paper introduced a compressed fluid-based separation process that combines carbon dioxide and ethanol to isolate portisins previously hemi-synthesized from blueberry surplus anthocyanins. The performance of the two-step separation process was compared favorably to centrifugal partitional chromatography (CPC) and conventional reversed-phase liquid chromatography (RPLC) findings that were reported in terms of portisins content in the extract, process throughput, process efficiency, and total solvent used.

Researchers investigated the use of electric field in dried blood spot (DBS) sample preparation for the detection of steroids in newborns using liquid chromatography-tandem mass spectrometry (LC-MS/MS) using both regular electroporation cuvettes and a custom vial setup.

A recent paper discusses advances in hydrophilic interaction chromatography (HILIC) in the analysis of therapeutic oligonucleotides and their impurities.

In this article, the editors of LCGC highlight some newly released laboratory products from instrument manufacturers around the world.

Exum Industries, producers of the first laser ablation laser ionization time of flight mass spectrometer (LALI-TOF-MS), announced a partnership with Edge Scientific to better promote and distribute their products.

The global portable spectrometer market is expected to reach over $4 million by 2030, according to a new market research report.

Researchers propose a suite of batch effect removal neural networks in large liquid chromatography-mass spectrometry experiments to maximize sample classification performance between conditions.

LCGC spoke with key opinion leaders on the cutting edge of analytical science (both from academia and the private sector) to gauge the evolution of a variety of techniques and the opportunities this evolution will present.

Researchers have utilized ultra-high performance liquid chromatography-tandem mass spectrometry (UH PLC-MS/MS) to monitor 5-Fluorouracil, a medication used to treat various cancers, in dried blood spots. This process offers a simpler, more efficient method than those in place involving the monitoring of plasma.

A report estimates that the market for chromatography software will grow at an 8.92% CAGR between 2023 and 2033.

A report estimates that the market for high performance liquid chromatography equipment will grow at a 4.61% CAGR between 2023 and 2033.

Richard Bade of the Queensland Alliance for Environmental Health Sciences (QAEHS) within The University of Queensland (Australia) and colleagues have recently published a paper outlining the development and application of a new workflow utilizing the open-source platform InSpectra, aiming to complement targeted analysis and identify geographical spatial trends in wastewater samples across multiple countries. Bade spoke to LCGC International about their research paper and the work that inspired it.

In this interview to commemorate Earth Day, Ana Torres-Agullo and Silvia Lacorte share the results of using Pyr-GC-Orbitrap-MS to simultaneously determine the presence of 10 polymers in the air.

This two-part session focused on metabolomics and lipidomics, to better understand the science of cellular biology.

Scientists at the Analytica conference in Munich, Germany, spoke about clinical mass spectrometry and its use in metabolomics and lipidomics.

In this interview, Kevin Schug discusses his work using untargeted analysis and differentiation of psilocybin mushroom strains.

At the 2024 Pittcon Conference, Elizabeth Humston-Fulmer of LECO Corporation presented an improved workflow which uses two-dimensional gas chromatography (GCxGC) with dual time of flight (TOF) MS/FID detection. Shortly after Pittcon, Humston-Fulmer discussed this analytical method with us.