Fracking activity in the northeast of the USA has rapidly increased over recent years, with over 8000 Marcellus wells drilled in the Marcellus Formation in Pennsylvania, USA, alone. Scientists in Pennsylvania investigating an isolated contamination incident have published data from their study, demonstrating the application of comprehensive 2D gas chromatography coupled with time-of‑flight mass spectrometry (GC×GC–TOF-MS) to investigate fracking contamination in a drinking water source.
Parabens are commonly used in cosmetics and personal care products to protect against microbial growth, but a new study suggests that manufacturers may also be using parabens in plastic teething products designed for infants. Scientists applied an effect-directed approach (to determine endocrine disrupting ability) to analyze teething products prior to chemical analysis using gas chromatography coupled to mass spectrometry (GC–MS). Of 10 products were tested, two were found to contain endocrine disrupting chemicals (EDCs).
Fast analysis of 14 banned carcinogenic aromatic amines using a Kinetex EVO C18 core-shell HPLC/UHPLC column with narrow peak widths along with excellent resolution between all compounds of interest.
Fast analysis of 14 banned carcinogenic aromatic amines using a Kinetex EVO C18 core-shell HPLC/UHPLC column with narrow peak widths along with excellent resolution between all compounds of interest.
Better detection, separation, and ionization of cannabinoids by a high pH LC/MS method method that utilizes a high performance Kinetex EVO C18 column.
Quantitative method to accurately monitor paraben levels in food and other personal care products using Novum Simplified Liquid Extraction (SLE) products in conjunction with a Kinetex EVO C18 5 μm core-shell HPLC column.
Better detection, separation, and ionization of cannabinoids by a high pH LC/MS method method that utilizes a high performance Kinetex EVO C18 column.
Quantitative method to accurately monitor paraben levels in food and other personal care products using Novum Simplified Liquid Extraction (SLE) products in conjunction with a Kinetex EVO C18 5 μm core-shell HPLC column.
Mass spectrometry (MS) is considered to be the gold standard in chemical detection due to the speed, selectivity, sensitivity, and versatility of the method. A miniaturized, linear ion trap, mass spectrometer can rapidly detect and unequivocally identify chemical targets that reduce the cost to analyze field samples and, more importantly, eliminate gaps in security because actionable information can be obtained on timescales that are relevant for security personnel
Ultra high resolution, accurate mass (UHRAM) mass spectrometry, based on the Thermo ScientificTM OrbitrapTM technology, is a powerful new approach to high throughput screening and quantitation in complex sample matrices. To learn more about how UHRAM is used in the Million Metabolome Project, an ambitious milestone for Exposome Research, LCGC talked with Dean Jones of Emory University.Click to view the associated whitepaper
A method is illustrated for the simultaneous analysis of nicotine, anabasine, and three of nicotine’s major metabolites (cotinine, nornicotine, and 3-hydroxycotinine) using the Kinetex 2.6 μm EVO C18 column.
Better identification and quantitation of low level peptides utilizing the powerful combination of unique selectivity and core-shell performance gains found with Kinetex EVO C18 core-shell columns.
Better identification and quantitation of low level peptides utilizing the powerful combination of unique selectivity and core-shell performance gains found with Kinetex EVO C18 core-shell columns.
A method is illustrated for the simultaneous analysis of nicotine, anabasine, and three of nicotine’s major metabolites (cotinine, nornicotine, and 3-hydroxycotinine) using the Kinetex 2.6 μm EVO C18 column.
Achieve excellent peak shape and resolution between the broad spectrum antibiotic cefaclor and its degredants using the unique selectivity and high efficiency of a Kinetex EVO C18 core-shell.
Achieve excellent peak shape and resolution between the broad spectrum antibiotic cefaclor and its degredants using the unique selectivity and high efficiency of a Kinetex EVO C18 core-shell.
Rapid and comprehensive resolution of a cold medicine API screen that can easily be implemented on HPLC and UHPLC instrumentation using a high performance core-shell Kinetex 2.6 μm EVO C18 column
Rapid and comprehensive resolution of a cold medicine API screen that can easily be implemented on HPLC and UHPLC instrumentation using a high performance core-shell Kinetex 2.6 μm EVO C18 column
A high performance, pH stable core-shell Kinetex EVO C18 column obtains narrow peak shape and extremely useful resolution for a doxylamine formulation impurity profile.
Highly sensitive and reliable screen of Benzodiazepines, Opiates, Synthetic Opioids, Amphetamines, Analgesics and Illicit Drugs
A high performance, pH stable core-shell Kinetex EVO C18 column obtains narrow peak shape and extremely useful resolution for a doxylamine formulation impurity profile.
Enjoy the unique Kinetex EVO C18 selectivity now in 1.7µm and 2.6µm particle sizes for your UHPLC work. This extremely versatile core-shell phase offers the high performance you crave, a unique all-purpose selectivity, and ruggedness you can depend on.
Enjoy the unique Kinetex EVO C18 selectivity now in 1.7µm and 2.6µm particle sizes for your UHPLC work. This extremely versatile core-shell phase offers the high performance you crave, a unique all-purpose selectivity, and ruggedness you can depend on.
Highly sensitive and reliable screen of Benzodiazepines, Opiates, Synthetic Opioids, Amphetamines, Analgesics and Illicit Drugs
Click the title above to open The Column June 05, 2015 Europe & Asia issue, Volume 11, Number 10, in an interactive PDF format.
Click the title above to open The Column June 05, 2015 North American issue, Volume 11, Number 10, in an interactive PDF format.
Click the title above to open the LCGC Europe June 2015 Recent Developments in HPLC and UHPLC Supplement, Vol 28, No s6, in an interactive PDF format.
Environmental sample analysis by large-volume injection (LVI) in combination with liquid chromatography–tandem mass spectrometry (LC–MS-MS) is described for polar and nonpolar analytes in both aqueous samples and organic extracts.