Mass Spectrometry

In this edition of The LCGC Blog, Jonathan Shackman discusses what factors to consider when choosing a mobile phase for liquid chromatography (LC) procedures.

A new process for tracking targeted and non-targeted fluorinated residuals using liquid chromatography–high-resolution mass spectrometry (LC–HRMS) has been created.

Scientists from the National Institutes for Food and Drug Control have characterized antibody-drug conjugates (ADCs) using various mass spectrometry (MS)-based techniques.

Here is some of the most popular content posted on LCGC International this week.

Using ultra-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS), China Pharmaceutical University scientists developed a new method for analyzing compounds found in wastewater.

Scientists from the China University of Sciences combined magnetic solid-phase extraction (MSPE) with gas chromatography–mass spectrometry (GC–MS) to analyze perfluoro carboxylic acids (PFCAs) in different water environments.

Here is some of the most popular content posted on LCGC International this week.

University of Valencia scientists recently developed a method using solid-phase extraction (SPE) followed by high-performance liquid chromatography coupled to high-resolution mass spectrometry (HPLC–HRMS/MS) for detecting microplastics and other harmful substances in textiles.

Spanish scientists recently tested flow injection analysis–mass spectrometry (FIA–MS) and its effectiveness in detecting fraudulent substances in Coleus forskohlii food supplements.

Here is some of the most popular content posted on LCGC International this week.

Jiangsu Police Institute scientists recently created a solid-phase microextraction (SPME)-based method for determining amphetamine-type stimulants.

University of Oslo scientists combined electromembrane extraction (EME) and flow injection-MS/MS (FI–MS/MS) to determine polar endogeneous metabolites in human plasma.

In this article, the use of comprehensive two-dimensional liquid chromatography (LC×LC) coupled to mass spectrometry (MS) for characterizing glycosylation of therapeutic enzymes is presented.

New gene therapy modalities, such as CRISPR guide RNA (single guide ribonucleic acid [sgRNA]) and messenger RNA (mRNA), continue to make progress in both primate and first-in-human trials. As this progress builds, the industry remains accountable for characterizing these molecules to meet the requirements of regulatory authorities.

In the first LCGC Blog of 2025, Caitlin Cain of the University of Michigan highlights the divide between gas and liquid chromatographers, and why both types of techniques should be in the same conversations.

In 2024, we launched a content series, covered major conferences, presented prestigious awards, and continued our monthly Analytically Speaking podcasts. Below, you'll find a selection of the most popular content from LCGC International over the past year.

Throughout 2024, the editors of LCGC International attended chromatography conferences across the globe. Below, you’ll find a sampling and overview of our conference coverage from the year.

This article highlights a curated selection of the most popular GC-related content, with a focus on the diverse applications of the technique, as featured in LCGC.

Schmitz's lab will now integrate the company’s structures for lossless ion manipulation (SLIM) technology into their research as part of this new partnership.

Webinar Date/Time: Wed, Jan 22, 2025 11:00 AM EST

Here is some of the most popular content posted on LCGC International this week.

Separation scientists frequently encounter critical pairs that are difficult to separate in a complex mixture. To save time and expensive solvents, an effective alternative to conventional screening protocols or mathematical peak width reduction is called iterative curve fitting.

Messina Institute of Technology scientists used gas chromatography–mass spectrometry (GC–MS) to profile illegal samples of Cannabis sativa L.

In the testing of six different oat brands, headspace sorptive extraction and comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry (GC×GC–TOF-MS) reveal how various packaging types can affect and alter the oats’ volatile profile, underscoring the potential impact of packaging on food quality.

The Chromatographic Society (ChromSoc) has announced the winners of the Martin Medal and the Silver Jubilee Medal for 2025. Professor Bogusław Buszewski of Nicolaus Copernicus University in Torun, Poland, has been awarded the prestigious Martin Medal, and the 2025 Silver Jubilee Medal has been awarded to Elia Psillakis of the Technical University of Crete in Greece.