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© 2022 MJH Life Sciences and Chromatography Online. All rights reserved.
© 2022 MJH Life Sciences™ and Chromatography Online. All rights reserved.
October 01, 2021
This study illustrates the importance of column selection during GC method development.
In recent years, top-down mass spectrometry has quickly advanced from academic rarity to (near-) routine. How did we get here? And what can we expect in the near future?
Recent developments in high-resolution mass spectrometry (HRMS) are aiding biopharmaceutical development and simplifying routine monitoring, with applications in areas like multi-attribute methods, coupling established purity methods with MS, and subunit analysis.
August 01, 2021
HS-SPME-GC–MS was combined with OPLS-DA data analysis to tentatively identify eight chemical markers to differentiate the geographical origins of cigar leaf samples.
July 01, 2021
Ensuring complete overlapping (coelution) of analyte and internal standard peaks can be critical for eliminating matrix effects in LC–MS/MS analysis.
This 7-minute method enables easy analysis of bitter flavors in beer.
At ChromTalks, experienced speakers shared mistakes made during their careers.
Mary Ellen McNally knows how to solve complex and pressing problems in the industry.
June 01, 2021
Modern ion mobility–mass spectrometry (IM–MS) is a key separation technology for detailed molecular characterization studies and also as part of emerging data acquisition strategies for demanding small molecule and several applications. Here is what you need to know.
May 01, 2021
Analysis of extractables and leachables (E&L) from plastic packaging is of great importance for pharmaceutical product safety. Accurate and rapid identification of unknown compounds in E&L is often complex and challenging. To address this challenge, we demonstrate a quick method for oligomer determination using LC–QTOF-MS.