Solid-Phase Extraction (SPE)

A new method for monitoring tricyclic antidepressants (TCA) in biological fluids and tissues in real time was proposed for the purposes of improving their effects or determining causes of death.

Extraction phase processes are well covered in literature, but lack of attention to the mechanism of these systems deprives researchers of information needed to evaluate their current and future use.

Researchers in Iran utilize graphene oxide aerogels to significantly improve the extraction and analysis of risperidone from plasma samples, offering enhanced accuracy and efficiency in pharmaceutical analysis.

Extraction of gasoline and its major aromatic groups was promising using a carbon nanotube-assisted solid-phase microextraction (CNT-SPME) fiber.

New MSPE-CE-DAD study indicates that efficiency remained above 75% even when a magnetic solid-phase extraction (MSPE) method was repeated five times, noting that the magnetic porous carbon (MPC) used in the extraction can be easily recycled.

Eighty drugs prohibited in athletic competition were analyzed, with seven samples returning adverse findings compared to previous methods.

A new method determines gas-polydimethylsiloxane (PDMS) distribution constants of key Cannabis terpenes and terpenoids, providing insights into their behavior and for optimizing SPME methods for analysis of these compounds.

This month we interview Juan L. Benedé from the University of Valencia in Spain, about his work developing microextraction approaches, based on the use of sorbent materials, for application to complex matrices, and his focus on the determination of disease biomarkers in biofluids.

A team of researchers from the University of Barcelona has developed a new method for the selective extraction of monosaccharide anhydrides from sediment samples, which is crucial for their analysis.

A solid-phase microextraction (SPME) Arrow combined with comprehensive two-dimensional gas chromatography coupled to mass spectrometry (GC×GC–MS) identified about 40 more volatile compounds in a variety of whiskeys compared to conventional SPME.

Scientists have developed a magnetic ionic liquid hypercrosslinked polymer composite for use in magnetic solid-phase extraction (MSPE) of non-steroidal anti-inflammatory drugs (NSAIDs), which was coupled with high-performance liquid chromatography (HPLC) for the detection of trace amounts of NSAIDs in water and urine samples.

Exploring the impact of green chemistry on analytical chemistry and GC is the focus of this instalment of "GC Connections".

This yearly report on new products introduced at Pittcon and in the preceding year covers sample preparation instruments, supplies, and accessories.

Direct-injection mass spectrometry (DIMS) and gas chromatography (GC) approaches have some significant differences that are pertinent when analyzing volatile organic compounds (VOCs). We explain.

Everyone is talking about sustainability, and organizations are creating sustainability programs. But what does green chemistry really mean, and how does it apply to gas chromatography?

Here's the scoop on the latest offerings in sample preparation.

Pesticides in local surface and groundwaters were purified and enriched with solid-phase extraction, then analyzed using multidimensional gas chromatography coupled to mass spectrometry, with the results compared to those found by gas chromatography–quadrupole mass spectrometry.

The development of antibiotics needs to constantly be evolving to counter bacterial resistance that can develop against these medications. Solid-phase extraction (SPE) can be used to combat this challenge.

Solid-phase extraction holds an important role in identifying and improving the effectiveness of antibiotics.

Solid-phase microextraction combined with mass spectrometry improves our ability for rapid drug screening.

The 25th edition of the International Symposium on Advances in Extraction Technologies (ExTech) will be held in Tenerife (Canary Islands, Spain) from 18–21 July 2023. Here’s a glimpse of what attendees can look forward to.

Online SPE–LC–MS/MS combined with the method presented enabled automated cleanup of food extracts and determination of PFAS compounds in the ng/kg range.

How to speed up sample prep time and equivalent acccuracy and precision.

A GC–MS method, coupled with magnetic SPE with multi-walled carbon-nanotube (MWCNT)-coated iron oxide as the adsorbent, was developed for analyzing organophosphate esters in environmental water samples.

Reducing matrix effects during LC–MS/MS bioanalysis is paramount. Improving sample preparation techniques is the best way to combat this issue.