
News|Videos|October 23, 2025 (Updated: October 22, 2025)
Sensitivity and Sensitivity for Oligos Using High Resolution Mass Spectrometry
The sensitivity and selectivity of high resolution mass spectrometry (HRMS) for oligonucleotide analysis is discussed.
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Episodes in this series

The future of high-resolution mass spectrometry (HRMS) and triple quadrupole mass spectrometry (QqQ-MS) is likely to involve continued improvements in both sensitivity and selectivity. HRMS is expected to become more accessible and faster, offering broader screening capabilities with high accuracy. Triple quadrupoles, however, will likely maintain an edge in targeted quantification due to their exceptional sensitivity and reproducibility. As technology advances, the panel discuss the potential of these approaches in the video above.
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