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Christine Fisher describes her method using mass defect filtering at the data acquisition stage to improve non-targeted PFAS detection in complex food matrices.

Headspace-gas chromatography-ion mobility spectrometry (HS-GC-IMS) combined with machine learning accurately detected fruit juice adulteration.

Blood markers reliably shifted toward healthy diet patterns after counseling.

Antonio Ferracane explains how each sample prep step adds error and can strip target PAHs, so skipping cleanup can improve recovery, accuracy, and precision.

Color imaging and high-performance liquid chromatography (HPLC) reliably predicted pigment levels in carrots.

Hydrophilic interaction chromatography-mass spectrometry (HILIC-MS) profiling tied a senescence gene region to chlorophyll loss and seed protein in sunflowers.

Antonio Ferracane discusses moving to minimal sample preparation for PAH analysis, and why matrix-matched calibration can replace cleanup steps.

Gas chromatography-mass spectrometry (GC-MS) revealed exercise-driven metabolic reprogramming supporting neurogenesis.

For scientists who depend on accurate, traceable data every day, the tools they use matter enormously. Sartorius, a global leader in biopharma research and manufacturing solutions, has introduced its latest generation of laboratory balance—the Cubis III—and it reflects how much the expectations placed on such instruments have changed in recent years.

Gas chromatography with flame ionization detection (GC-FID) showed fermented cassava peel added to chicken feed optimized yolk fatty acid profile in eggs produced.

Electromembrane extraction (EME) uses electric fields and liquid membranes for selective, green microextraction compatible with chromatography.

Antonio Ferracane outlines a combined technique using cryogenic peak compression and pseudo-MRM to sharply boost sensitivity for trace PAHs.

Advancing Miniaturized Column and Instrument Technologies for Capillary Liquid Chromatography
Recent developments in column technology and instrumentation for use in capillary-scale liquid chromatography are discussed. Key motivating factors for the increase in capillary liquid chromatography (LC) usage include a desire for more sustainable analytical methods (including reductions in solvent usage and waste generation) and the need for compact, field-portable systems that can be used in point-of-need settings. To achieve these goals, miniaturization strategies for both column and instrument designs have been required. The impact of these innovations in a variety of application areas—including environmental analysis, forensic testing, and pharmaceutical and biopharmaceutical manufacturing—is described. As the need for greener analytical methods continues to grow, the implementation of low-flow capillary-scale separations will also increase.

Isotope dilution liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS) linked higher sleep apnea risk to lower testosterone and sex hormone-binding globulin (SHBG) levels.

HPLC pharmaceutical analysis sometimes requires wavelengths beyond a drug's maximum UV absorption for optimal detection.



















