John Chasse

LCGC International spoke to Sandy Al Bardawil and Ludivine Ferey, authors of a review article summarizing recent advances in chromatographic methods coupled with MS for the characterization of therapeutic oligonucleotides.

High performance liquid chromatography (HPLC) verifies creatine uptake via two distinct transporter genes in rainbow trout.

This week's Chromatography Online highlights span LC solvent mismatch solutions, advanced PFAS monitoring by GC–MS and TD–GC–MS, deep learning in DIA proteomics, multidimensional LC–MS for plant extracts, PEG column guidance, and LC–MS/MS and GC–MS applications in consumer product safety and disease research.

Liquid chromatography-mass spectrometry (LC–MS) plasma nicotine data trains machine learning (ML) models for vaping exposure.

Gas chromatography–mass spectrometry (GC–MS) was used in the profiling of links between gut bacteria and metabolites to myasthenia gravis.

High performance liquid chromatography (HPLC) and inductively coupled plasma mass spectrometry (ICP-MS) reveal how diet and sunlight shape grey parrot nutrient levels.

High performance liquid chromatography (HPLC) reveals sugar, acid, and phenolic differences in varieties of grapes.

Gas chromatography-mass spectrometry (GC-MS) and gas-chromatography with flame ionization detection (GC-FID) identify volatile organic compound (VOC) emissions from yard and food waste compost.

High-performance liquid chromatography (HPLC) reveals how burn pit smoke disrupts blood vessels, lungs, and the brain.

Gas chromatography–mass spectrometry (GC–MS) identifies 27 sugar compounds across sweet corn kernel development.

Liquid chromatography-tandem mass spectrometry (LC–MS/MS) testing reveals preservative limit breaches in Danish shampoos and soaps.

Researchers have developed an advanced gas chromatography-mass spectrometry (GC–MS)-based chromatographic method for faster and more sensitive detection of volatile and semi-volatile PFAS in soil, improving environmental monitoring of “forever chemicals” and related contaminants. LCGC International spoke to Maria Chiara Corviseri and Flavio A. Franchina of the University of Ferrara, two of the authors of a paper presenting their method.

Ion-exchange chromatography (IEC) revealed tree species-driven differences in soil carbon and microbial life.

This week, Chromatography Online compiled peer-reviewed research, expert interviews, and news articles spanning chromatography and spectrometry in food analysis.

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) revealed vitamin D deficiency strongly linked to childhood obesity.

Headspace-gas chromatography-ion mobility spectrometry (HS-GC-IMS) combined with machine learning accurately detected fruit juice adulteration.

Blood markers reliably shifted toward healthy diet patterns after counseling.

Color imaging and high-performance liquid chromatography (HPLC) reliably predicted pigment levels in carrots.

Hydrophilic interaction chromatography-mass spectrometry (HILIC-MS) profiling tied a senescence gene region to chlorophyll loss and seed protein in sunflowers.

Gas chromatography-mass spectrometry (GC-MS) revealed exercise-driven metabolic reprogramming supporting neurogenesis.

Gas chromatography with flame ionization detection (GC-FID) showed fermented cassava peel added to chicken feed optimized yolk fatty acid profile in eggs produced.

Isotope dilution liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS) linked higher sleep apnea risk to lower testosterone and sex hormone-binding globulin (SHBG) levels.

Researchers recently developed fluorinated solid phase microextraction (SPME) materials that improve the selective extraction and chromatographic detection of volatile per- and polyfluoroalkyl substances (PFAS) from complex samples. LCGC International spoke to the authors of the paper resulting from this work.

Gas chromatography-mass spectrometry (GC–MS) and liquid chromatography-mass spectrometry (LC–MS) identify volatile and nonvolatile flavor drivers shaping lager liking among high-flavor-preference consumers.

MOH contaminants in food pose safety risks, making reliable chromatographic detection essential.

Chromatographic mega-methods screen multiple mycotoxins, advancing food exposomics and public safety.

Liquid chromatography-coupled tandem mass spectrometry (LC-MS/MS) and high-resolution mass spectrometry (HRMS) reveal how glycoalkaloids transform in fried potato products.

This week’s Chromatography Online website covered HTC-19 highlights, GC maintenance tips, CapLC challenges, and oligonucleotide troubleshooting.

Gas chromatography-mass spectrometry (GC-MS) and high-resolution metabolomics (HRMs) reveal how ergot alkaloids disrupt steer metabolism.

Liquid chromatography-high resolution mass spectrometry (LC-HRMS) metabolomics reveals wastewater and stormwater impacts on mussel health.