
This article presents applications of ELSD in GPC/SEC. It discusses both the advantages and disadvantages as well as the practical considerations for use in GPC/SEC.

This article presents applications of ELSD in GPC/SEC. It discusses both the advantages and disadvantages as well as the practical considerations for use in GPC/SEC.

In this technical tip from CHROMacademy we re-visit some of the lesser known or remembered facts relating to silica particles used in chromatography.

Click here to view the full European E-newsletter from October 3.

An excerpt from LCGC's e-learning tutorial on translating GC methods at CHROMacademy.com

The Urine Metabolome Database (UMDB) (www.urinemetabolome.ca) containing detailed information on over 3000 metabolites has been launched following the comprehensive quantitative metabolome characterization of urine by scientists at the University of Alberta, Canada.1 The project is part of the on-going Human Metabolome Project launched in 2005 by Genome Canada and Genome Alberta, and has so far received $600 million in funding from the Canadian government.

Environmental and pharmaceutical application, forensics, material and food production analyses – Shimadzu’s HS-20 headspace sampler serves GC and GCMS applications particularly in testing and inspection organizations.

Malvern Instruments (Malvern, UK) has acquired NanoSight (Amesbury, UK), a nanoparticle characterization company. The acquisition was completed on 27 September 2013.

Peak Scientific has recently opened an extension of their head office in Inchinnan, Scotland, named Cherry Tree House. The extension will accommodate the expansion of the company since it launched in 1997.

Mobile Phase Reservoirs from Corning

PYREX HPLC Mobile Phase Reservoir, Single Cavity

Lab Innovations 2013

The experimental design that considers gradient time and temperature was expanded to include a third factor, either pH or ternary composition, and modelling software facilitated the analysis.

The parameters that should be considered in the optimization of HPLC methods are explained and then illustrated through the analysis of two commercial agricultural products.

Supercritical fluid chromatography has become a viable option for the separation scientist in diverse areas, and the field now seems more adequately described as an extension of HPLC, or perhaps as "carbon dioxide–based HPLC".

The authors explain modern UHPLC instrument design and outline simple procedures to identify causes of poor column and method performance.

When choosing the articles to include in this supplement, my selection was based on a very simple criterion.

Click the title above to open the LCGC Europe October 2013 Recent Developments in HPLC and UHPLC Supplement, Vol 26 No s10, in an interactive PDF format.

John Hinshaw examines the anatomy of chromatographic peaks with attention to features that help determine the suitability of individual chromatographs for a specific analysis task.

The innovative and inspiring career of Barry Karger is described, including his pioneering work in bioanalysis.

There are many parameters that need to be considered when considering the use of hydrogen as a carrier, however, the benefits to chromatography and money saved make this a worthwhile exercise.

In any field, there are "misconceptions" or "myths" that arise and are perpetuated and passed on to the next generation. These myths are often driven by a lack of understanding of the real issues by practitioners. In the first of a two-part feature from Ron Majors, the top 10 high performance liquid chromatography (HPLC) column myths are presented and attempts are made to demystify them by offering some evidence that they are untrue. This part will feature myths 10 to six.

The Eastern Analytical Symposium (EAS) will be held this year from November 18 to 20, 2013, in Somerset, New Jersey. EAS is the second largest conference and exposition for laboratory science in the United States dedicated to the needs of analytical chemists and those in the allied sciences.

There are many parameters that need to be considered when considering the use of hydrogen as a carrier. Even so, the benefits to chromatography and money saving make this a worthwhile exercise.

Highlights of the column technology observed at the symposium

The latest applications for carbon nanotubes in chromatography and sample preparation are outlined.

A tribute to John Dolan, who is celebrating 30 years of writing the "LC Troubleshooting" column.

The application of gas chromatography (GC) combined with atmospheric pressure chemical ionization mass spectrometry (GC–APCI-MS) and with supersonic molecular beam ionization mass spectrometry (GC–SMB-MS).

What's happened in the last 30 years? What will happen next?

LCE June 2013 BPA