
HPLC pharmaceutical analysis sometimes requires wavelengths beyond a drug's maximum UV absorption for optimal detection.

HPLC pharmaceutical analysis sometimes requires wavelengths beyond a drug's maximum UV absorption for optimal detection.

Researchers recently developed fluorinated solid phase microextraction (SPME) materials that improve the selective extraction and chromatographic detection of volatile per- and polyfluoroalkyl substances (PFAS) from complex samples. LCGC International spoke to the authors of the paper resulting from this work.

"Peak to Plate: Expert Insights in Food Analysis" brings you exclusive insights from chromatography professionals on the front line of food analysis.

In "Peak to Plate: Expert Insights in Food Analysis,” we present a compilation of the latest news articles and peer-reviewed content that highlight the utility of chromatography in food analysis. Happy reading!

Giorgia Purcaro from the University of Liege (Belgium) discusses a laboratory technique for more accurately detecting harmful oil contaminants in edible oils than the current official method.

During her PhD at BOKU University Vienna, Lidija Kenjerić developed a multi-class UHPLC–MS/MS quantitative method covering 931 mycotoxins and secondary metabolites within an 11-min runtime, providing a scalable solution for routine testing, regulatory, and emergency response.

Gas chromatography-mass spectrometry (GC–MS) and liquid chromatography-mass spectrometry (LC–MS) identify volatile and nonvolatile flavor drivers shaping lager liking among high-flavor-preference consumers.

Stefan Van Leuwen and Jana Pulkrabova—co-chairs of RAFA 2026—elaborate on why separation scientists involved in food analysis should attend RAFA 2026, which takes place at the Clarion Congress Hotel Prague, Prague, Czech Republic, from November 3–6, 2026.

MOH contaminants in food pose safety risks, making reliable chromatographic detection essential.

LCGC International spoke to Maria Halabalaki, an associate professor at the National and Kapodistrian University of Athens, about how dried spot microsampling could transform food testing.

Ana Rodríguez-Bernaldo de Quirós of the University of Santiago de Compostela discusses how non-targeted gas chromatography–mass spectrometry (GC–MS) can reveal complex chemical mixtures in bioplastic food packaging, raising important safety questions and concerns for consumers.

Chromatographic mega-methods screen multiple mycotoxins, advancing food exposomics and public safety.

Liquid chromatography-coupled tandem mass spectrometry (LC-MS/MS) and high-resolution mass spectrometry (HRMS) reveal how glycoalkaloids transform in fried potato products.

Click here to access the LCGC International May/June 2026 European PDF in an interactive format.

This week’s Chromatography Online website covered HTC-19 highlights, GC maintenance tips, CapLC challenges, and oligonucleotide troubleshooting.

Gas chromatography-mass spectrometry (GC-MS) and high-resolution metabolomics (HRMs) reveal how ergot alkaloids disrupt steer metabolism.

Click here to access the LCGC International May/June 2026 North American PDF in an interactive format.

Ultra-high purity helium for gas chromatography.

Liquid chromatography-high resolution mass spectrometry (LC-HRMS) metabolomics reveals wastewater and stormwater impacts on mussel health.

Targeted liquid chromatography-mass spectrometry (LC-MS) metabolomics identifies plasma biomarkers for lung cancer screening.

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) reveals how soccer training intensity shifts athletes' hormone levels.

Gas chromatography-mass spectrometry (GC-MS) analysis of 90 basil varieties identifies top chemotypes for industrial use.

Liquid chromatography LC troubleshooting for oligonucleotides: fix peak splitting, denaturation smearing, and metal-surface adsorption to boost recovery.

Hans-Gerd Janssen explores the reality of real-time analytical measurement.

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) urinary analysis ties volatile organic compound (VOC) and polycyclic aromatic hydrocarbon (PAH) exposure to oxidative stress in children.

This gas chromatography-quadrupole orbital trap high-resolution mass spectrometry (GC-Q-Orbitrap HRMS) method detects 215 pesticides in high-fat peanut matrices reliably.

Capillary liquid chromatography (CapLC) offers compelling advantages in sensitivity, solvent reduction, and compatibility with modern mass spectrometry, yet remains underutilized in routine analytical workflows. This article synthesizes expert discussions from a Pittcon 2026 networking session to examine why CapLC adoption has lagged despite decades of development. Key themes include educational gaps, instrumentation limitations, robustness concerns, detection challenges, and supply‑chain constraints. The discussion highlights areas where CapLC already delivers clear value—such as proteomics, oligonucleotide analysis, and high‑throughput screening—and outlines practical pathways for broader adoption through targeted applications, improved instrumentation, and redefined expectations of “routine” chromatography.

30% of GC–MS peak annotations and integrations have been observed to be inaccurate. Hans-Gerd Janssen highlights some of the most promising strategies to improve data reliability and reduce errors.

Hans-Gerd Jansses discusses problems associated with LC–MS peptide identification data with sensory perception and the identification of specific tastants for food analysis.

A non-targeted HRMS approach using data prioritization and ion mobility MS identified unsuspected PFAS in food, expanding coverage beyond targeted methods.