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In the second part of our interview with Michael Shortreed, he reflects on how his work is used in laboratories worldwide and discusses those who mentored him throughout life.

LCGC International's April series for National Cannabis Awareness Month concludes with a discussion with Walter B. Wilson from the National Institute of Standard and Technology’s (NIST’s) Chemical Sciences Division regarding recent research his team conducted investigating chromatographic interferences that can potentially inflate the levels of Δ9-THC in Cannabis sativa plant samples, and possible solutions to avoid this problem.

In the first part of our interview with Michael Shortreed, we discuss his winning the Al Yergey MS Scientist Award and learn about his research on computational methods.

Here is some of the most popular content posted on LCGC International this week.

Come and meet the International Women in Chromatography at HPLC 2025 in Bruges, Belgium.

The United Kingdom banned menthol as a characteristic flavor in cigarettes in May 2020. Researchers tested cigarettes sold in 2021–2022 for menthol and other characterizing flavors through sensory and chemical testing, using gas chromatography–mass spectrometry (GC–MS) in their research.

Two-dimensional liquid chromatography (2D-LC) coupled to mass spectrometry (MS) has been used to separate proteins in the venom of the Indian cobra snake.

Researchers leveraged the advantages of thermodesorption, followed by comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC×GC/TOF-MS), to compare and assess a variety of sampling phases for body odor.

As part of the collaboration, BASF will contribute its R&D expertise in catalytic materials and technologies, while Mingyang will focus on applying its research capabilities to Power-to-X equipment.

Here is some of the most popular content posted on LCGC International this week.

Green analytical chemistry is no longer a niche concept but a necessity in today’s environmentally conscious world.

We spoke with Josh Hoerner, general manager of Purisys, which specializes in a small volume custom synthesis and specialized controlled substance manufacturing, to gain his perspective on FDA’s recommendations for acceptable intake limits for N-nitrosamine impurities.

A new collaboration facility, opened by Thermo Fisher Scientific, will work to make cell therapy developers’ research more accessible and optimized.

The critical role of separation science in per- and polyfluoroalkyl substances (PFAS) research highlights just how essential chromatography is in solving complex challenges that benefit society.

Researchers used liquid chromatography–mass spectrometry (LC–MS) in their proteomic analysis to compare the serum proteome of migraine patients with healthy controls and to identify differentially expressed proteins as potential migraine biomarkers.

Imre Molnár, president of the Molnár-Institute for Applied Chromatography, will be presented with the Tswiett-Nernst European Award at the ISSS conference in September 2025.

In a commentary published in Environmental Health Perspectives, researchers voiced concerns about the limitations in PFAS research due to restricted access to high-purity reference standards.

In a commentary published in Environmental Health Perspectives, researchers voiced concerns about the limitations in PFAS research due to restricted access to high-purity reference standards.

Researchers investigating the relationship between cannabis use during pregnancy and depressive symptoms—and whether continued use beyond the first trimester or higher levels of use were linked to increased symptoms—used liquid chromatography–tandem mass spectrometry (LC–MS/MS) to confirm the presence of 11-nor-9-carboxy-delta-9-tetrahydrocannabinol (THC-COOH) in urine samples.

University of Valladolid scientists used a miniaturized method for analyzing biogenic volatile organic compounds (BVOCs) emitted by tree species, using headspace solid-phase microextraction coupled with gas chromatography and quadrupole time-of-flight mass spectrometry (HS-SPME-GC–QTOF-MS) has been developed.

The proposed tariffs by the Trump administration on various industries may have implications for analytical chemists across industry, government, and academia.

A combination of liquid chromatography ion mobility spectrometry, and high-resolution mass spectrometry (LC–IMS-HRMS) for non-targeted analysis (NTA) was used to detect and identify per- and polyfluoroalkyl substances (PFAS) in alligator plasma.

Catharina Capitain and Melanie Schüßler from the Faculty of Geosciences at the University of Tübingen, Tübingen, Germany describe a novel approach using matrix-matched semiquantification to investigate per- and polyfluoroalkyl substances (PFAS) in contaminated soil.

A joint study conducted by the University of Ferrara (Italy) and the Council for Agricultural Research and Economics (Rome, Italy) focused on the analysis of terpenes and terpenoids—key bioactive compounds responsible for the distinctive flavor and potential therapeutic effects of cannabis. For this study, the research team used comprehensive two-dimensional gas chromatography coupled with mass spectrometry (GC×GC-MS) coupled with dynamic headspace extraction (DHS) to profile these compounds in cannabis inflorescences. LCGC International spoke to Flavio A. Franchina of the University of Ferrara, corresponding author of the paper which resulted from this study, about their research.

The American Society for Mass Spectrometry has announced its award winners for 2025, including Jack Henion of Cornell University and Vilmos Kertesz of Oak Ridge National Laboratory.

Here is some of the most popular content posted on LCGC International this week.

In the final part of this interview, Ralph Mead and his group at the University of North Carolina, Wilmington, discuss the biggest challenges in mitigating the effects of PFAS right now. Here’s the final part of our conversation with the Mead Group at UNC Wilmington.

An automated solid-phase extraction (SPE) method has been developed to detect cyanotoxins in water.