
Rapid chromatography-free method enables untargeted detection of food adulterants for quality control.

Rapid chromatography-free method enables untargeted detection of food adulterants for quality control.

James P. Grinias from Rowan University, Glassboro, New Jersey, United States, is the winner of the 2026 HTC Innovation Award, which was presented at the Hyphenated Techniques and Separations Technology (HTC-19) conference in Leuven, Belgium, on Friday May 29, 2026. The award is co-sponsored by the HTC conference and LCGC International.

Using two-column chromatography, a 63.6-fold purified cold-active amylase from potato peel waste shows strong starch-processing potential.

Headspace solid-phase microextraction gas chromatography-mass spectrometry (HS-SPME-GC-MS) identified key aroma compounds differentiating peaches and nectarines by flesh type.

Vaughan Langford discusses the application of automated selected ion flow tube mass spectrometry (SIFT-MS) analysis to diverse high-throughput food analysis applications, including sensory-correlated analysis, authentication, and ingredient screening.

The first session at HTC-19 in Leuven on Wednesday 27 May 2026 kicked off with an inspiring tryptch of speakers —Caroline West, Leon Barron, and Jackie Mosely—exploring innovative aspects of modern hyphenated chromatography.

An illuminating session called AI and Modelling on Wednesday 27 May 2026 at HTC-19 in Leven, Belgium focused on automated and computational approaches to LC method development, with five presentations spanning Bayesian optimization, hybrid retention modelling, QSAR-based retention prediction, graph-theoretic peak alignment, and functional data analysis

Bingchuan Wei describes how to cultivate a culture of innovation and calculated risk-taking while operating within the compliance demands of biopharmaceutical drug development.

Researchers used orbital ion trap liquid chromatography-tandem mass spectrometry (LC-MS/MS) to separate and identify proteins in human eye lens fiber cells.

DEAE-cellulose and gel filtration chromatography purify a selective B. stercoris milk-clotting protease.

High-end mass spectroscopy innovation is driven by proteomics, leaving scientists in other fields like drug development, environmental analysis, and metabolomics underserved.

Ionic liquids (ILs) are structurally tunable salts that pose unique analytical challenges.Ionic liquids (ILs) are structurally tunable salts that pose unique analytical challenges. This article reviews how mass spectrometry is used to study IL ion clusters, dissociation pathways, and decomposition products, with a focus on applications in spacecraft propulsion and environmental contamination.

Bingchuan Wei shares practical guidance for early-career scientists seeking to transition into industry drug development across diverse therapeutic modalities.

Discover the latest advances in metabolomics, LC–MS workflows, spectral libraries, and untargeted analysis during this morning session featuring researchers from academia, government, healthcare, and industry.

Join analytical scientists and instrument experts for a dynamic session showcasing the latest innovations in GC–MS instrumentation, high-throughput workflows, untargeted analysis, and trace-level detection technologies.

Join leading researchers and industry experts for an in-depth session on emerging contaminants, PFAS detection, and non-target analysis strategies shaping the future of environmental testing.

Untargeted liquid chromatography-mass spectrometry (LC-MS) and molecular networking reveal seasonal pollutant shifts and emerging contaminants in South Africa’s Nylsvley wetland.

Gas chromatography-mass spectrometry (GC-MS) quantified para-chloroaniline (PCA) formed in root canals, with sodium ascorbate as a final rinse proving most effective.

Bingchuan Wei reflects on how to connect high-level patient and medical goals to the highly technical analytical tools required to meaningfully support ADC drug development decisions.

Using chromatography-based analysis, researchers demonstrate how complementary alcohol biomarkers can help distinguish between recent binge drinking and repeated alcohol consumption in forensic driving investigations.

Researchers developed and validated a LC–MS/MS method for the detection of antibacterial, antifungal, and antiparasitic residues in legume-based alternative protein products. LCGC International spoke to Awanwee Petchkongkaew and Chanita Boonkanon, corresponding and lead authors, respectively, of the paper outlining this work.

Supercritical CO₂ extraction of limoncello-derived lemon peels, followed by gas chromatography-mass spectrometry (GC–MS) analysis, revealed monoterpene-rich chemical profiles with antioxidant, antimicrobial, and skin-beneficial potential, supporting their value as sustainable cosmetic ingredients.

Fernando Lanças discusses miniaturized liquid sample preparation for greener LC–MS/MS workflows in environmental analysis, favoring SUPRAS and DES solvents.

HIC-MS, ADC characterization, career insights, and aroma and protein detection research highlight this week’s website offerings.

Using liquid chromatography–mass spectrometry (LC–MS), researchers compared arterial and venous oxylipin profiles in obese and non-obese heart failure with preserved ejection fraction (HFpEF) patients and identifies distinct obesity-associated lipid mediator patterns linked to more severe pulmonary hypertension.

Using liquid chromatography–mass spectrometry (LC-MS) and machine learning, researchers identified distinct steroid hormone patterns in chronic versus episodic cluster headache that may help differentiate disease subtypes and point to adrenal-related involvement.

Paweł Wiczling from the Medical University of Gdańsk, Poland describes some of the practical benefits that artificial intelligence/machine learning (AI/ML) can offer separation scientists. Pawel will present on this topic at Extech 2026, which will take place at the University of Liege, Gembloux, Belgium from July 6–9 2026.

Using gas chromatography–mass spectrometry (GC–MS), researchers compared volatile flavor compounds formed in chicken breast treated with free iron, heme iron, and hemoglobin, showing that each iron type alters fat oxidation pathways and resulting aroma profiles differently.

Bingchuan Wei discusses how robust ADC characterization strategies meet regulatory expectations and how stronger methodologies can accelerate candidate selection to clinical approval.

Gas chromatography–olfactometry–mass spectrometry (GC-O-MS) combined with a Sensomics approach showed that laboratory and pilot-scale pervaporation produce grape spirits with highly similar aroma profiles and no significant differences in key odor-active compounds or consumer preference.