All News

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) shows soaking, ultrasound cut popcorn acrylamide levels by 82%.

Does high-performance liquid chromatography (HPLC) analysis show that melittin alone can't predict bee venom quality?

A worrying trend has emerged in UK higher education: the systematic erosion of deep, hands-on chromatography instruction and delivery of this key technique by non-experts, according to Tony Edge, President of The Chromatographic Society (ChromSoc). Can this trend be reversed?

LCGC International spoke to the University of Salerno’s Eduardo Maria Sommella and Danila La Gioia regarding a new hydrophilic interaction liquid chromatography-high resolution mass spectrometry (HILIC-HRMS) method which quantifies circulating analytes to help detect liver cancer.

Gaëlle Spileers from the Separation Science Group in the Department of Organic and Macromolecular Chemistry at Ghent University, Belgium discusses developments in high performance liquid chromatography (HPLC–XRF) for the analysis of brominated flame retardants and other pollutants.

The panel closes with a shared message: define your question first, and remember every result is an estimate.

Gaëlle Spileers from the Separation Science Group in the Department of Organic and Macromolecular Chemistry at Ghent University, Belgium discusses developments in high performance liquid chromatography (HPLC–XRF) for the analysis of brominated flame retardants and other pollutants.

High-performance liquid chromatography (HPLC)-verified caffeine dose eased mental fatigue from nap deprivation in a recent pilot study.

Chromatography of tooth layers links prenatal pollutants to autism risk.

High-pressure liquid chromatography with tandem mass spectrometry (HPLC-MS/MS) was used to determine whether there is a link between serum PFAS and breast density.

Gas chromatography-mass spectrometry (GC-MS) and gas chromatography-olfactometry (GC-O) pinpoint key odorants behind soybean off-flavor profiles.

Asked for one change to ease PFAS analysis, the panel points to better communication and smarter use of AI tools.

Melissa Dunkle, senior research scientist at Dow Benelux BV, The Netherlands, explores practical aspects of using multidimensional pyrolysis gas chromatography (Pyr-GCxGC) to investigate fluoropolymer degradation.

High-resolution liquid chromatography-tandem mass spectrometry (HRLC-MS/MS) reveals how low-oxygen burials preserve ancient brain proteins.

Soil chromatography reveals how fluridone herbicide persists in cotton farmland.

The experts compare direct injection and solid-phase extraction for handling PFAS in complex matrices.

Gas chromatography-mass spectrometry (GC-MS) reveals how alcohol and acidity shape climate-linked wine aroma compounds.

The panel tackles the paradox of background contamination: the lower detection limits go, the more PFAS turn up everywhere.

Gas chromatography (GC) shows ultrasound-treated pea starch reduces oil in fried corn starch foods.

Daniel Vik from Amgen Research Copenhagen, Denmark discusses the motivation behind applying machine learning to chromatographic retention time prediction and its growing importance in modern pharmaceutical research. He shares insights into the challenges of developing robust predictive models, their role in supporting high-throughput drug discovery workflows, and the potential of artificial intelligence to make analytical chemistry more efficient and scalable.

Bryan Vining, David Megson, and Pasquale Avino examine why ultrashort-chain PFAS like TFA are reshaping analytical priorities.

Low-pressure gas chromatography-triple quadrupole mass spectrometry (GC-MS/MS) quantifies 37 volatile PFAS in food packaging in 8 minutes.

Melissa Dunkle, senior research scientist at Dow Benelux BV, The Netherlands, discusses the revival of interest in pyrolysis gas chromatography.

Jie Du of Cardinal Health discusses with LCGC International how switching from reversed-phase to hydrophilic interaction liquid chromatography (HILIC) can unmask a hidden excipient artifact mistaken for a true leachable.

Liquid chromatography-tandem mass spectrometry (LC-MS/MS reveals antibiotics, PFAS, and toxic metals in cat kibble.

This week, Chromatography Online featured conversations from ASMS 2026 on untargeted MS/MS quantitation, RPLC-HRMS analysis of PLGA copolymers, and AI/ML predictions for non-targeted LC–ESI–HRMS workflows, alongside expert debate on harmonizing PFAS analytical methods and a sensor GC study examining whether water chasers affect alcohol metabolism.

Atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry (AP-MALDI-MS screens black pepper for fraud with minimal preparation.