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Mass spectrometry–based techniques, including cross-linking and covalent labeling, were used to show how phosphorylation and oxidation alter alpha-synuclein structure, providing insight into how these modifications may influence aggregation and neurodegenerative disease. LCGC International spoke to Ian Webb, corresponding author of a paper that resulted from this research.

"GC Connections" column editor Nicholas Snow offers a basic GC maintenance tools and supplies overview.

Gas chromatography-mass spectrometry (GC-MS) headspace analysis identifies dimethyl disulfide as a microbial marker in spacecraft wastewater.

ASMS 2026 highlighted AI-driven MS software, faster/deeper proteomics, spatial biology imaging, biopharma characterization tools, PFAS monitoring, and greener instrumentation.

This week’s LCGC International website offerings span AI, food, forensics, and clinical therapy.

Gas chromatography coupled with mass spectrometry and ion mobility spectrometry was used to identify volatile compounds shaped by fermentation time and drying temperature in black tea.

2026 ASMS awards honor advances in native MS, single-cell proteomics, metabolomics, and instrumentation, spotlighting mass spectrometry's scientific impact.

ASMS 2026 highlights a potential paradigm shift in metabolomics, as new evidence suggests many unknown signals are ESI artifacts.

Hans-Gerd Janssen highlights the important innovations and challenges remaining using hyphenated separation science techniques in food analysis.

HPLC 2026 session on AI in separations science, covering LC–MS, modelling, peak integration and digital method development.

A two-part session on biopharmaceutical analysis will be held at HPLC 2026 on Monday, June 8.

Bo Zhang from Xiamen University, Xiamen, China discusses his upcoming lecture at HPLC 2026 that reveals a new way to design and manufacture chromatographic materials. This new approach indicates that chromatographic media can be intentionally engineered rather than developed through “trial-and-error” synthesis. By independently controlling particle morphology and pore architecture, separation materials can be rationally designed and optimized for specific applications

This week at the ASMS Annual Conference, Peak Scientific unveiled its latest nitrogen generator, the Genius NEO, describing it as the most advanced product in the company's history

High-performance liquid chromatography (HPLC) reveals how cherry variety, tissue type, and freezing method affect beneficial compound levels.

A dual isotope dilution tandem mass spectrometry (IDMS) method reliably detects 24 pesticides in cucumbers, revealing widespread safety limit breaches.

High-performance liquid chromatography (HPLC) measured blood dopamine in Parkinson's patients on LCE or LB, revealing no significant difference.

Gas chromatography-tandem mass spectrometry (GC-MS/MS) reveals first-trimester phthalate exposure impairs fetal growth, worsened by maternal stress.

Chromatography and spectrometry techniques reveal how high-heat cooking alters fatty acid profiles in three vegetable oils.

In this month's LCGC Blog, Katelynn Perrault describes a new initiative to promote the importance and practice of chemometrics through an active-learning programme that provides hands-on experience with chemometric workflows using real analytical datasets.

Bruker debuts advanced proteomics, metabolomics, and ultra-high-resolution mass spectrometry (MS) platforms at ASMS.

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) reveals widespread PFAS, bisphenols, parabens, and benzophenones in Andalusian household dust.

Thermo Fisher’s three new mass spectrometer platforms, AI-driven software acquisitions, and integrated workflows aim to reduce analytical tradeoffs across complex scientific markets

Researchers studied oxygenated species formation in nitazene analogs via DART-MS to improve forensic drug screening and address the opioid crisis. LCGC International spoke to Emma Hardwick, lead author of the paper that resulted from this work.

Gas chromatography-mass spectrometry (GC-MS) reveals cultivation-driven shifts in volatile organic compound (VOC) profiles of vanilla orchids without loss of compound diversity.

New R tool auto-decodes polyol structures from mass spec data—great for screening complex formulas.New R tool auto-decodes polyol structures from mass spec data—great for screening complex formulas.

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) quantification of deflazacort metabolites in urine and plasma validates the World Anti-Doping Agency's 30 ng/mL detection threshold.

A session on Thursday 29 May 2026 at HTC-19 in Leuven, Belgium called The Power of The Hyphen brought together five presentations exploring the application of multidimensional and coupled chromatographic methods to complex analytical challenges in food and beverage, petroleum, environmental, and pharmaceutical applications.