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In this article, you’ll find some of the top content that was published on LCGC this week, including a technical article on food flavor and an interview with the president of Shimadzu Europa.

The panel concludes by envisioning the future of PFAS research and analysis.

A recently published study set out to determine whether serum metabolic signatures inform on the relationship between healthy lifestyle and colon cancer risk. Serum samples were analyzed using liquid chromatography-mass spectrometry (LC-MS).

The conversation turns to collaboration—highlighting the value of cross-sector partnerships in advancing PFAS science, securing funding, and fostering scientific progress.

Can the peony, a plant having a long history of consumption and medicinal value in China, play a role in the treatment of type 2 diabetes mellitus? Researchers using liquid chromatography-tandem mass spectrometry (LC-MS/MS) and high-performance liquid chromatography (HPLC) set out to find the answer.

Panelists discuss the creation and use of PFAS libraries and databases, stressing the need for comprehensive, up-to-date resources to support accurate compound identification.

A study conducted by researchers at the University of British Columbia (Vancouver, Canada) used gas chromatography coupled with flame ionization detection (GC-FID) to develop an automated sampling protocol applied to indoor rooms of a cannabis cultivation and a cannabis processing facility to investigate the temporal concentration profile and emissions of 22 terpenes.

Scientists examine the role of non-targeted analysis in discovering unknown PFAS, and how automation and data processing tools are accelerating this work.

In the final moments of our time with Tian (Autumn) Qiu, winner of the ASMS 2025 Research Award, she discusses what initially drew her to the conference and what makes her enjoy returning.

In this episode the panelists unpack how laboratories can reduce background contamination and improve sensitivity through rigorous method optimization and instrument handling.

The panelists discuss the challenges of analyzing short-chain PFAS and highlights how emerging techniques like ion mobility offer promising solutions.

New upgrades to the Waters Corporation Alliance iS HPLC System Software systems were recently discussed at HPLC 2025.

Here is some of the most-read content posted on LCGC International this week.

In the fourth section of our time with Tian (Autumn) Qiu, winner of the ASMS 2025 Research Award, she discusses the mentors who guided her to where she is now and imparts advice to future mass spectrometrists.

In this episode the panelists explore emerging analytical techniques that are enhancing PFAS quantification.

An LC×LC–HRMS method was developed for the characterization of phenolic compounds in cannabis, with flavoalkaloids identified for the first time.

In the third section of our time with Tian (Autumn) Qiu, she discusses how mass spectrometry can be useful in environmental toxicology research.

A study conducted by the College of Veterinary Medicine of Midwestern University (Glendale, Arizona), the University of California Davis School of Veterinary Medicine (Davis, California) and the College of Veterinary Medicine of the University of Tennessee (Knoxville, Tennessee) set out to describe the pharmacokinetics of oral gabapentin (GABA) in goats given as a single dose (SD) and multidose (MD) regimen, as well as to document any adverse effects after administration. Plasma samples were collected and analyzed via reversed-phase high performance liquid chromatography (RP-HPLC).

The experts explore the most pressing analytical challenges in PFAS analysis, highlighting persistent issues such as contamination, detection limits, background blanks, and other method-related obstacles encountered in the lab.

A joint study between the Nursing School of North Henan Medical University (Xinxaing, China) and The First Affiliated Hospital of Harbin Medical University (Harbin, China) used gas chromatography–mass spectrometry (GC-MS) for an observational study collecting and classifying surgical smoke generated during laparoscopic surgery to evaluate the carcinogenic risks to healthcare workers.

A recap of the afternoon session focused on pharmaceutical separations, from Day 2 of HPLC 2025.

A recent review conducted by the Food Science Departments of Cairo University (Giza, Egypt), the University of Basrah (Basrah, Iraq) and Damascus University (Damascus, Syria) examined the wide array of bioactive compounds present in plant-based foods, with emphasis on their extraction, isolation, identification, characteristics, and emerging applications. These compounds were separated, purified, and analyzed from their complex plant-based matrices through a variety of chromatographic and spectrometric techniques.

A recap of the morning session focused on method development, from Day 2 of HPLC 2025.

Highlights from the afternoon sessions of HPLC 2025: Oligonucleotide analysis

Highlights from the opening session and the first day of HPLC 2025

As a precursor to the Lindau Nobel Laureate Meetings, Texas A&M University held a meeting for future Lindau attendees to highlight the institution’s scientific facilities. One such attendee is Caitlin Cain of the University of Michigan, one of LCGC International’s 2024 Rising Stars of Separation Science.

In the food industry, evolving consumer demands, contamination concerns, and workforce issues are driving significant changes in food analysis and instrumentation.

Here is some of the most-read content posted on LCGC International this week.