Application Notes: General

GCxGC TOFMS analysis can be overwhelming, but ChromaTOF Tile can quickly compare these data sets to bring statistically significant differences to the forefront.

A fast separation of remdesivir and its active metabolite GS-441524 for the treatment of COVID-19 is obtained in only 3 minutes using a YMC-Triart C18 UHPLC column.

Estrone, beta-estradiol, and estriol were derivatized from plasma using Novum PRO 96-Well Plates SLE to provide less background noise.

In this application, serum was cleaned up and compared with both a single protein precipitation protocol and also by the addition of a phospholipid removal product.

Miniaturized LC–MS and SPE method for the reliable and accurate detection of viral pesticides at 1 fmol/uL using SARS-CoV-2 nucleocapsid protein as a model system.

A quantitative LC–MS/MS method using a room-temperature hydrolysis with an advanced SPE product for the analysis of designer and pharmaceutical benzodiazepines in urine

An in-well hydrolysis solid-phase extraction (SPE) product is used for an easy clean-up solution for the urine sample matrix to save time and transfer steps.

Testosterone was isolated from plasma using Novum PRO 96-well plates SLE sample preparation.

An SLE media provides a fast sample prep method. Adding advanced manufacturing processes leads to high recoveries and low variation between samples.

In this application, serum was cleaned up and compared with both a single protein precipitation protocol and also by the addition of a phospholipid removal product.

Detailing how thermal desorption GC–MS can be used to monitor the release of PFAS during the application of aqueous film-forming foam

This brief demonstrates the extraction and analysis of PFAS compounds in water following EPA method 537.1, using PS2 solid-phase extraction and LC–MS/MS.

Workflows for non-targeted analyses for PFAS in wastewater and soil samples are demonstrated using a Xevo G2-XS QTof coupled with an ACQUITY UPLC.

This brief demonstrates the extraction and analysis of 25 PFAS compounds from water samples using Oasis WAX for PFAS SPE cartridges, according to EPA 533 methodology.

Read a case study about how an environmental laboratory meets the challenges of increased sample throughput, trace detection, and complex matrices for PFAS testing.

An application for extraction and analysis of PFAS from human serum utilizing weak anion exchange (WAX) chemistry and Xevo TQ-S micro.

Waters has been a pioneer in PFAS analysis, providing total application solutions that include UPLC columns, sample preparation chemistry, LC–MS/MS systems, and more.

Unispray ionization is compared to typical electrospray for the analysis of PFAS in environmental samples. 

A robust and reliable solution for monitoring for 40 PFAS compounds including replacements like HFPO-DA, and short-chain analytes.