Application Notes: General

Highly selective and sensitive quantitation of eight nitrosamines in metformin drug products using a single LC-SRM-MS method

Today’s challenges in targeted quantitation involve more than just measuring concentrations of target analytes. Gains in productivity are achieved through new hardware and software features.

This application note demonstrates the use of an LC-MS system test for assessing the expected performance level based on protein digest sample and defined LC-MS PQAs.

Learn how artificial intelligence empowered search transforms your proteomics data processing with Proteome Discoverer software and CHIMERYS search engine.

This application note outlines the analysis of PFAS in drinking water according to EPA 533 using UCT’s Enviro-Clean® polymeric weak-anion exchange (WAX)SPE cartridges. 

In this application note we demonstrate the excellent performance of Sapiens-624MS columns for the analysis of e-liquids based on ISO 20714

A ZipChip CZE system coupled to Bruker maXis II UHR-QTOF affords deep profiling of charge variants of highly heterogeneous mAbs such as cetuximab

This application note demonstrates the benefits of HPTLC/HPTLC PRO compared to TLC on the example of identity testing of sorbitol.

Now you can measure over 7000 proteins in a 70 min LC separation while using a standard 4D-Proteomics™ approach. Learn more. 

H2O2 is often used as an oxidizing agent in toothpaste. A fast and sensitive method is presented to allow the quantitation of hydrogen peroxide in less than 3 min.

This note reviews the process of extraction of synthetic and naturally occurring cannabinoids in urine using SPE and LC–MS/MS using UCT’s SSHLD extraction cartridge.

Reviews the highly retentive but universal nature of UCT’s polymeric Styre Screen® HLD sorbent for analysis of barbiturates, benzodiazepines, and THC in oral fluid.

A simple and robust method for the detection of 16 cannabinoids in hemp and cannabis samples using a rugged isocratic HPLC method coupled with UV detection.

A solid-phase extraction method utilized to extract 19 synthetic cannabinoids produced recoveries in the range of 85–110% with corresponding RSD values of less than 5%.

Get a better understanding of how ion chromatography plays an important role in pharmaceutical research and development.

A solid-phase microextraction (SPME) gas chromatography–mass spectrometry (GC–MS) method for analysis of smoke damage impact in wines is demonstrated.

Novel food authenticity workflow for routine analysis allows discrimination of black pepper samples from different geographic regions, and detection of adulteration.

A GC–MS single quadrupole mass spectrometer is demonstrated for the detection and quantification of vegetable oil adulteration in milk fat samples.

The use of solid-phase microextraction (SPME) yields fast, solvent-less, selective analysis in static headspace gas chromatography.

Determination of 2- and 3-MCPD Fatty Acid Esters in Infant Formula Using GC–MSD Abstract: This application note describes a reliable analytical method for determining the fatty acid esters (3-MCPD and 2-MCPD) in infant formula using GC–MS.

This application note provides an example of a novel food authenticity workflow that can be used for food classification and detection of food fraud using GC–QTOF-MS.

This application note demonstrates the significant benefit in extraction efficiency of the Agilent DVB/carbon WR/PDMS SPME Arrow (1.1 mm) larger sorption phase volume.