Application Notes: General

The application successfully separates the 7 typical ions including F-, Cl-, NO2-, Br-, NO3-, PO43-, and SO42-, and it fulfills US EPA Method 300.1 (A) requirements.

This application introduces the automated analysis of fluorescent diastereomers of the proteinogenic D/L-amino acids using derivatizing reagents with chiral structures.

The seven main anions can be separated quickly using the IC NI-424 column. Improvement has been made in the separation of chloride and nitrite ions.

Fused-Core® Technology benefits PFAS analysis for fast, efficient, and rugged separations which are paramount to environmental analysis.

HALO® PFAS and PFAS Delay columns are application verified columns well suited for challenging environmental sample analysis.

High throughput analysis of 33 PFAS compounds found across EPA methods 533, 537.1, and 8327 in under 5 minutes.

HALO® PFAS delay and HALO® PFAS analytical columns deliver rugged, reproducible performance for the most challenging environmental sample matrices.

Rapid and high-resolution analysis of PFAS compounds across EPA methods 537.1, 533, and 8327, using the new HALO® PFAS delay and analytical columns.

This goal of this note is identity confirmation of protein-based impurities of a therapeutic protein by multi heart-cut 2D-LC–MS in a top-down experiment.

King Estate Winery is one of the biggest and best producers in Oregon, U.S. Read about their success story of sustainable growth rooted in quality control.

The fight against cancer employs many tools. Paclitaxel, a compound found in the bark of the Pacific yew tree, is one that that has been found to make a big difference.

This application demonstrates excellent performance in method development for the analysis of raw materials for oligonucleotide synthesis using a biocompatible UHPLC.

Six nitrosamines are separated using a YMC-Triart C18 UHPLC column. This is challenging due to the commonly observed small peaks thanks to low impurity concentrations.

A simple and sensitive method is presented for the analysis of glyphosate and its metabolite AMPA in drinking water, using the ALEXYS HPAEC-PAD analyzer.

The ALEXYS HPLC-ECD Analyzer was used for the assay of Streptomycin sulphate in commercial pharmaceutical preparations, according to the official USP monograph.

An easy method is described for the analysis of nitrate and nitrite (E249 - E252) in food products, using the ALEXYS HPLC-UV analyzer.

HPLC with electrochemical detection is the method of choice for water- and fat-soluble vitamin analysis including ubiquinols.

The sensitive analysis of carbohydrates in instant coffee, based on an adapted ISO 11292:1995 method, is shown using the ALEXYS Carbohydrates Analyzer.

A fast and sensitive method is described for the analysis of phytosterols (sterols and stanols) using the ALEXYS HPLC-ECD analyzer equipped with a BDD WE electrode.

Impurity analysis of β-cyclodextrin in sulfobutyl ether β-cyclo-dextrin sodium according to the exact method described in the USP monograph.

Gentamicin sulphate analysis in pharmaceutical preparations according to the official USP (37-NF32) and EP monograph (8.0) using the ALEXYS HPLC-ECD analyzer.

Three variable lengths of oligo-DNA and phosphorothioated oligo-DNA separated without an ion pair reagent, using the Shodex™ HILICpak™ VT-50 2D.

This application note demonstrates that oligo analysis using ZipChip CE/MS offers a quick, dilute-and-shoot analysis without the need for toxic ion-pairing agents.

This application note demonstrates that oligo analysis using ZipChip CE/MS offers a quick, dilute-and-shoot analysis without the need for toxic ion-pairing agents.

Stereoisomeric separation between solifenacin succinate and its stereoisomers occurs using the Lux® 5 µm Amylose-1 Column according to the USP monograph.

Sildenafil citrate assay and organic impurities are identified as in the US Pharmacopeia (USP) monograph with both core-shell and fully porous C18 HPLC columns.