Application Notes: General

A collaboration to move biopharma forward. Symphogen has deployed Chromeleon CDS for both routine chromatography and cutting-edge MS workflows.

The internal standard module of a CDS thermal desorber is used to automate the process of preparing calibration standards onto pre-conditioned thermal desorption tubes

This application note demonstrates the quantitative recollection of split sample to a clean sample saver tube for a group of VOCs in TD–GC–MS.

This application note follows the Pyroprobe application decision making tree with EGA and pyrolysis to study biodegradable plastics by GC-MS.

In this application note, we will walk you through the steps required to change your carrier gas from helium to hydrogen.

Download this guide to learn the strategies to consolidate chemical reference parameters and population biomarker analysis to support the wastewater-based epidemiology.

This application note demonstrates the robust SPE LC–MS methodology of the Microlute® CP Reverse Phase SPE 30 mg plates on a range of neutral, acidic, and basic analytes.

In this application note, we explore using a phosphate-containing buffer for aggregate analysis of an IgG2 mAb, panitumumab, which has known recovery issues.

Fc-fusion proteins are Fc homodimers linked to a polypeptide chain. Fc-fusion proteins offer several challenges: They have more complex glycosylation as well as O-glycans.

In this application note, we demonstrate a priming protocol, where 10 injections of BSA are injected into a packed 150 x 4.6 mm i.d. column with sub-2 µm particles.

This guide provides a comprehensive application overview for Biozen dSEC size exclusion columns.

In this application note, we demonstrate the SEC separation of recombinant human growth hormone (rhGH), somatotropin.

In this application note, we demonstrate the robustness of a sub-2 µm SEC column. Over 300 injections of a protein sample (Myoglobin) were performed.

In this application note, we explore arginine as a mobile phase cosolvent that improves high molecular weight aggregate recovery for size exclusion chromatography.

This guide provides an overview of the Biozen size exclusion chromatography columns for the analysis of monoclonal antibodies, biosimilars, and other biomolecules.

The versatile selectivity and high temperature limit of Zebron ZB-624plus provides a one column GC-FID solution to cannabis residual solvent and terpenes testing.

An expanded list of 15 mycotoxins for LC–MS/MS analysis is shown with a simple solvent and modified QuEChERS salt extraction. The workflow is simple and accessible.

The California list covers a wide range of pesticides with diverse chemical properties. This LC–MS/MS method features increased resolving power for the multiresidue pesticides of interest.

Flash chromatography is widely used for purifications in pharmaceutical product synthesis and is now finding similar application in CBD -THC remediation.

Six nitrosamines are separated using a YMC-Triart C18 UHPLC column. This is challenging due to the commonly observed small peaks thanks to low impurity concentrations.