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This week, LCGC International published a variety of articles on hot topics in separation science. From an interview about the latest advancements in supercritical fluid chromatography (SFC), a news article about a new product from Thermo Fisher, and an article about bioanalytical liquid chromatography–mass spectrometry (LC–MS), we’ve highlighted some of the most popular articles that were published this week.

Researchers at the Spanish National Research Council’s Institute of Marine Research published a review article exploring MS-based approaches for the detection and quantification of seafood allergens, with a focus on technological advancements, current challenges, and future perspectives to enhance food safety and regulatory compliance.

Researchers evaluated hair care formulations containing 0.5–1.5% fractionated patchouli oil (LFPO) for antidandruff activity against M. globosa and hair growth effects in male rabbits. LFPO, derived from crude patchouli oil (CPO), was characterized using GC-MS to enhance efficacy.

Portrait of a Female Lab Scientist at Work in a Modern Medical Research Facility. Bioengineer in a White Coat Handling Test Tubes and Putting Them Inside an Advanced Machine for Analysis | Image Credit: © Gorodenkoff - stock.adobe.com.

In the fifth part of this roundtable discussion focused on the experiences, challenges, and contributions of Women in Chromatography, LCGC International spoke to Noor Abdulhussain, Lotte Schreuders, and Mimi den Uijl—co-founders of the Sisters in Science initiative—about how industry and academia can offer better support for women in STEM.

Lotte Schreuders, Noor Abdulhussain, and Mimi Den Uijl © Image courtesy of the Sisters in Science

In the fourth part of this roundtable discussion focused on the experiences, challenges, and contributions of Women in Chromatography, LCGC International spoke to Noor Abdulhussain, Lotte Schreuders, and Mimi den Uijl—co-founders of the Sisters in Science initiative—about how popular chromatography is as a subject.

The panelists introduce themselves and outline their practical experience and knowledge of oligonucleotides, setting the stage for an illuminating discussion on current challenges, solutions and innovations in this ten-part panel discussion series organised by LCGC International in collaboration with the Chromatographic Society (ChromSoc).

Building on the initial discovery of unidentified extractable organic fluorine (EOF) in Greenland killer whale blubber, researchers characterized EOF in additional specimens and identified some of their origins using gas chromatography-atmospheric pressure chemical ionization-high resolution mass spectrometry (GC-APCI-IMS).

The concept of dark omics refers to the significant proportion of uncharacterized molecular features within complex biological samples that are often present yet remain inaccessible or unidentified by conventional analytical techniques. This article explores how ion mobility spectrometry integrated with mass spectrometry (IM‑MS) provides critical solutions to longstanding challenges in accessing these dark regions across metabolomics, proteomics, lipidomics, and emerging areas, such as exposomics.

Researchers from the University of Campinas (Campinas, Brazil) and the Waters Research Center (Budapest, Hungary) introduced a rapid, automated method using laser-assisted rapid evaporative ionization mass spectrometry (LA-REIMS) with high-resolution mass spectrometry to fingerprint coffee samples and predict sensory properties. LCGC International spoke to Leandro Wang Hantao of the University of Campinas regarding their work and the paper that resulted from it.

doctor scientist female test tube laboratory advancing healthcare innovation research experimentation vector illustration design  | Image Credit: © SachiDesigns - stock.adobe.com.

In the third part of this roundtable discussion focused on the experiences, challenges, and contributions of Women in Chromatography, LCGC International spoke to Noor Abdulhussain, Lotte Schreuders, and Mimi den Uijl—co-founders of the Sisters in Science initiative—to ask what advice they would offer to young women aspiring to enter a STEM career.

The RGB model, which combines red (analytical performance), green (environmental impact), and blue (practicality), is at the heart of the concept of white analytical chemistry (WAC). While this approach has helped broaden the field’s focus and offered a more balanced evaluation system, analytical science continues to move forward, and with it come new priorities that extend beyond what the RGB framework can fully reflect. This final article of this week's series on WAC curated by Adrián Fuente-Ballesteros of the University of Valladolid (Spain) presents new tools intended to fill that gap.

Portrait of a Female Lab Scientist at Work in a Modern Medical Research Facility. Bioengineer in a White Coat Handling Test Tubes and Putting Them Inside an Advanced Machine for Analysis | Image Credit: © Gorodenkoff - stock.adobe.com.

In the second part of this roundtable discussion focused on the experiences, challenges, and contributions of Women in Chromatography, LCGC International spoke to Noor Abdulhussain, Lotte Schreuders, and Mimi den Uijl—co-founders of the Sisters in Science initiative—about how the group has evolved over the last four years.