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Plasma samples from 47 patients with stages 1– 4 chronic kidney disease were analyzed with liquid chromatography-mass spectrometry to identify early biomarkers of the disease’s progression through metabolic pathway analysis.

A multi-faceted approach consisting of targeted quantitation, chemical profiling, and suspect screening via ultra-high performance liquid chromatography-high-resolution mass spectrometry (UHPLC-HRMS) determined the environmental and health risks stemming from crumb rubber recycled from end-of-life tires and repurposed for a variety of uses, including artificial turf fields.

A recent study of 56 Italian ciders utilizing comprehensive two-dimensional gas chromatography coupled to time-of-flight-mass spectrometry (GC×GC–TOF-MS) detected the presence of approximately 130 semi-volatile organic compounds.

A recent study analyzed nearly 100 CBD products to test the accuracy of advertised cannabinoid content.

In a new study, researchers explored the dynamics of immune gene expression, ruminal metabolome, and gut microbiota in cows.

At HTC-18 in Leuven, Executive Editor of LCGC International, Alasdair Matheson, spoke to Brett Paull from the University of Tasmania and HyTECH about his talk entitled: “Analytical Performance and Disruptive Potential of Fully Portable Portable and Field Deployable LC–MS Technology.”

Using nanoflow liquid chromatography electrospray ionization in tandem with mass spectrometry (LC-ESI-MS), researchers were able to assess baleen whale blubber and proteins extracted from that blubber.

The Agricultural Biotechnology Research Institute of Iran (Tabriz, Iran) recently utilized gas chromatography-mass spectrometry (GC-MS) to explore the impact of different animal sources and regions in Iran on the metabolome profiles of traditional yogurts.

A recent study used liquid chromatography tandem-mass spectrometry (LC-MS/MS) for a targeted proteomics analysis to establish cerebrospinal fluid-based proteomic panels for accurate primary central nervous system lymphoma diagnosis and differentiation.

LCGC International recently asked analytical scientists in industry and academia to share how mentorship has impacted their careers.

The editors of LCGC International explore how chemists can set themselves apart in an ever-competitive job market, highlighting the latest data in salary and employment statistics.

The article discusses the classification and characterization of GC×GC column sets based on polarity and orthogonality, introducing a standardized approach using a reference mixture called the Century Mix to evaluate the selectivity and performance of these column sets.

In this article, we discuss the fundamentals of headspace extraction, including static versus dynamic extraction, establishing equilibrium in the vial, consequences of the partition coefficient, temperature, pressure, and transfer to the gas chromatograph.

A rapid, accurate, and quantitative method for the analysis of glucosinolates (GSLs) has been achieved through the combining of column-free liquid chromatography (LC) with direct-infusion mass spectrometry (DIMS).

Recent research utilizing tandem mass spectrometry has yielded a complete set of expressed globulin genes, which code for the main storage protein in oats as well as their chromosomal positions.

The 28th International Symposium on Separation Sciences (ISSS 2024) will be held in Messina, Italy, on September 22–25, 2024.

Researchers at the Guangdong Key Laboratory for Veterinary Drug Development and Safety Evaluation have developed a high-performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) method for the precise detection of dimetridazole (DMZ) and its metabolite 2-hydroxymethyl-1-methyl-5-nitroimidazole (HMMNI).

In this “Equipment Roundup,” the editors of LCGC International feature new instruments from Thermo Fisher and Waters, and news from Knauer regarding the environmental impact of their best-selling HPLC systems, as recently assessed by My Green Lab.

In a new study, researchers analyzed serum proteomics of advanced adenoma (AA) and colorectal cancer (CRC) using liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) and data independent acquisition methods, screening for a variety of differentially expressed proteins.

LCGC International spoke to Silvia Valverde and Ana María Ares of the University of Valladolid about their research focusing on determining nine plasticizers in honey samples by gas chromatography–mass spectrometry (GC–MS).

At HTC-18 in Leuven, Executive Editor of LCGC International, Alasdair Matheson, spoke to Jef Focant from the University of Liege about his talk entitled, “Targeted Blood Lipidomics of Colorectal Cancer."

During a presentation at the conference in Denver, Colorado scientists from Merck and Novilytic spoke about chromatography techniques used for different kinds of pharmaceutical analysis.

At HTC-18 in Leuven, Executive Editor of LCGC International, Alasdair Matheson, spoke to this year’s winner of the 2024 HTC-18 Innovation Award, Bob Pirok from the University of Amsterdam, about his innovative research on automated LC method development.

At HTC-18 in Leuven, Executive Editor of LCGC International, Alasdair Matheson, spoke to Leon Barron from Imperial College London about his innovative research focusing on modern chromatographic techniques for analyzing contaminants of emerging concern in drinking water.

At HTC-18 in Leuven, Executive Editor of LCGC International, Alasdair Matheson, spoke to Chiara Cordero from the University of Turin about the evolving role of AI and its effect on GCxGC in foodomics.

PEAK Scientific, a provider of laboratory gas generation solutions, has opened a new facility in South Korea.

Research by Himanshi Upadhyaya & John V. Goodpaster of the Department of Chemistry and Chemical Biology, Indiana University Indianapolis has focused on using an odor-permeable membrane device (OPMD) to determine any changes in the odor of dynamite and have utilized gas chromatography–mass spectrometry in negative chemical ionization mode in all analysis.

Tarun Anumol of Agilent Technologies discusses the biggest challenges laboratories are experiencing in PFAS testing along with some potential solutions.