Environmental Analysis

A hybrid HILIC–ion exchange column was used for the analysis of ultrashort-chain per- and polyfluoroalkyl substances (PFAS) compounds in environmental waters. This direct injection LC–MS method enables simultaneous measurement of ultrashort- chain, alternative, and legacy PFAS in potable and non-potable waters.

A comprehensive monitoring protocol has been developed using GC–MS/ECD in selective ion monitoring (SIM) mode, with injection performed by solid-phase microextraction (SPME) and headspace (HS). This single system has been configured to analyze for all taste and odor (T&O) compounds in Standard Method 2170, with minimal changing of columns, injectors, or SPME fibers between methods.

This article explores the role of SPE sorbents for analyte recovery rates and method accuracy to develop clean samples for analysis and to reach lower limits of detection.

Environmental laboratories with high sample throughput often wish to analyze PCDD/Fs and PCBs in separate fractions. The cleanup method described here results in complete separation, and offers an alternative to fully manual or fully automated cleanup.

Microplastic pollution in the environment is a major concern for governments and companies worldwide attempting to understand and reduce the damage they cause. As well as the direct damage these plastic pellets can also act as chemical reservoirs that leach chemical contaminants into the environment and further damage ecosystems. The Column spoke to Manuel Miró from the University of the Balearic Islands, Spain, about his research into the pollution caused by chemical leaching from microplastics.

Environmental analysis of water presents many challenges, one of which is the potential presence of unknown contaminants. LCGC spoke to Imma Ferrer, an associate research scientist at the University of Colorado, USA, about some of her recent research on nontargeted analysis of water, including water from wastewater treatment plants, hydraulic fracturing wastewater, and environmental water samples.

LC–MS techniques, particularly those using high-resolution MS and nontargeted analysis, are advancing many areas of water research. Here, Imma Ferrer of the University of Colorado shares some of her recent work in this field.

Researchers have developed an alternative method to reduce interferences for the analysis of N-nitrosamines using GC coupled to HR-QTOF-MS.

In this study, the intentional incorporation of an air bubble into a solvent droplet is proposed for fully automated bubble-in-drop microextraction–gas chromatography–mass spectrometric (BID-GC–MS) analysis of selected organochlorine pesticides as model analytes.

The environmental analysis community sorely needs a system by which new and up-to-date methods are more easily developed, shared, and adopted.

Per- and polyfluoroalkyl substances (PFAS) are chemicals found in fire‑fighting foams and consumer products requiring water-resistant and stain-repellent properties. As a result of their unique chemical properties and long‑term widespread usage, these chemicals are an emerging human health concern. US Environmental Protection Agency (EPA) released analytical methods for PFAS measurement in 2009 and most recently in November of 2018. In this article, data generated using these methods with allowed analytical modifications is presented and demonstrates robustness and reproducibility while achieving low level detection limits in drinking water.

Polycyclic aromatic hydrocarbons (PAHs) and their oxygenated derivatives (oxy-PAHs) are highly toxic carcinogens that present a significant hazard to human health. To fully understand the risks associated with exposure to PAHs, robust analytical methods for their detection are required. Mass spectrometry coupled with ultrahigh-performance liquid chromatography (UHPLC–MS) has proven to be a powerful technique for the analysis of these compounds. This article looks at the benefits of using atmospheric-pressure chemical ionization (APCI) in the place of traditional electrospray ionization (ESI) for the detection of oxy-PAHs.

In this interview, Thomas Letzel of the Technical University of Munich considers the current state of water analysis, looking at recommended techniques, the growth of nontargeted screening, and multi-disciplinary collaboration.

Traditional sample preparation method development can often be laborious and costly. Understanding the underlying concepts of the technique can help food and environmental laboratories develop methods in notoriously complex matrices, faster, more efficiently, and provide better chromatography. With the presence of many unique matrices and analytes, methods such as QuEChERS, supported liquid extraction (SLE), or solid-phase extraction (SPE) provide the necessary adaptability for many types of extractions. With customizable methods to work with unique matrices and with the addition of automation, extractions can be improved to save time and provide consistent recoveries.

The Royal Society of Chemistry’s Environmental Chemistry Group, Water Science Forum, and the Separation Science Group Joint Meeting will be held on Friday 22 February 2019 in the Science Suite of the Royal Society of Chemistry, in Burlington House, Piccadilly, London, UK.

This applicate note presents the use of an automated solid-phase extraction (SPE) system to improve the accuracy and precision of semivolatile extractions, in compliance with EPA Method 8270.

When a company wishes to commercialize a new pesticide, they must conduct environmental studies and develop analytical methods capable of detecting the pesticide, and its metabolites, in soil and water samples. The methods must be robust and rugged, for easy use in routine analysis. James Stry, a principal investigator at FMC Agricultural Solutions, recently talked to LCGC about best practices he and his team have established for developing such methods, including approaches to meeting a variety of requirements of regulatory bodies, simplifying sample preparation, dealing with matrix effects, choosing an ionization method, and streamlining method development.

This article describes a direct analysis of glyphosate, aminomethylphosphonic acid (AMPA), glufosinate, and 3-methylphosphinicopropionic acid (MPPA) in water by liquid chromatography coupled to tandem mass spectrometry (LC–MS/MS) without derivatization. The chromatographic separation was performed using a hydrophilic interaction liquid chromatography (HILIC) column and typical LC–MS mobile phases. Method performance was evaluated, showing excellent results. The low limits of quantification (LLOQs) obtained meet the requirements of EU guidelines and could also be used to get an agreement in France where regulations require lower LLOQs (NOR: DEVL1703763V).

The Column spoke to Núria Fontanals, a senior researcher at the Department of Analytical and Organic Chemistry, Universitat Rovira i Virgili, Spain, about her work investigating the impact of artificial sweeteners as environmental pollutants using hydrophilic interaction chromatography (HILIC) and the broader role of HILIC in environmental analysis.

Snezana Agatonovic-Kustrin, a professor in pharmaceutical chemistry at Monash University, in Kuala Lumpur, Malaysia, spoke to The Column about the development of a method to evaluate antidiabetic and antioxidant activity in marine algae using high-performance thin-layer chromatography (HPTLC)-direct bioautography.

I do not remember the application, but I remember very clearly Professor McNair telling us that soil is one of the most challenging sample matrices, if not the toughest, from which to perform analytical determinations. Sources indicate the composition of soil ideal for growing plants to be 25% air, 25% water, 45% minerals, and 5% organic matter. That does not seem like a daunting makeup, but the reality is that the relative proportion of the constituents can vary dramatically.

Per- and polyfuorinated alkyl substances (PFAS) are a rapidly growing environmental and human health concern. Owing to their broad commercial use, chemical stability, and bioaccumulation potential, these compounds are widely dispersed in the environment and can cause exposure through many potential pathways. To adequately estimate exposure risks, analytical methods are required that can measure low levels of PFAS compounds in many types of matrices. As will be described, recent advances in solid-phase extraction (SPE) and liquid chromatography tandem mass spectrometry (LC–MS/MS) have enabled the identification and quantification of a large number of PFAS compounds at low concentration (

LCGC Europe spoke to Andrew Turner, Principal Chemist in the Food Safety Group at the Centre for Environment, Fisheries, and Aquaculture Science (Cefas) in Weymouth, UK, about developing a simple ultrahigh-pressure liquid chromatography tandem mass spectrometry (UHPLCÐMS/MS) method for the quantitation of microcystins and nodularin in various sample matrices.