LCGC Interviews

In preparative chiral supercritical fluid chromatography (SFC), adding 2.5–5% water cuts retention times and narrows collection windows, boosting throughput.

Princeton Chromatography's Jeff Caldwell says SFC can now complete separations in 10–15 seconds.

Perception, not technology, remains the biggest barrier to supercritical fluid chromatography (SFC) adoption, says JASCO's Tom DePhillipo.

Erin Chambers reflects on two leadership philosophies and a personal mantra that have shaped her approach to leading teams.

Erin Chambers shares her near-term and long-term view of how artificial intelligence will shape the chromatography community.

UHPLC–MS/MS and GC×GC methods are cutting food-safety testing times while quantifying hundreds of mycotoxins and mineral oil hydrocarbons at once.

Erin Chambers connects trustworthy data to scientific confidence and describes how Waters builds regulatory readiness into development.

A two-dimensional gas chromatography-time-of-flight mass spectrometry method detects legacy pesticides and PCBs below guideline levels.

A new study revealed Australian drinking water contained 0.3–0.7 μg/L nanoplastics and 0.5–1.5 μg/L microplastics. Polypropylene nanoplastics were identified, with 10⁶–10⁷ particles/mL in tap water.

Erin Chambers outlines the signals Waters tracks when deciding where to invest R&D across GLP-1s, lipid nanoparticles, mRNA, and ADCs.

Erin Chambers explains why she views column chemistry, not hardware, as chromatography's real differentiator, citing two recent Waters launches.

Marinella Vitulli calls formal cross-laboratory proficiency testing, not better detection technology, the field's biggest gap in NIAS analysis.

Ruling out false-positive NIAS annotations using triplicate testing and matched oven blanks rather than spectral criteria alone.

LCGC International launches "Beyond the Critical Point: Expert Insights in SFC," a topic takeover exploring SFC's science, evolution, and real-world applications.

Ranking non-intentionally added substance (NIAS) risk by consumer exposure and packaging use-case, not by hazard data alone.

Marinella Vitulli finds concentrated extracts reveal a broader contaminant profile than simulant migration tests, but filtration risks introducing cross-contamination.

The identification-confidence framework used to rank suspect and non-intentionally added substance (NIAS) detections is discussed.

Marinella Vitulli explains how her lab prioritizes and updates its PFAS and bisphenol screening libraries as new analogues emerge.

Summary: A preview of 2026 separation science trends, from PFAS and SFC to metabolomics, next-generation HPLC columns, oligonucleotides, and ADC analysis.

Hans-Gerd Janssen explores the industry's shift from fully integrated online systems to at-line approaches.

A worrying trend has emerged in UK higher education: the systematic erosion of deep, hands-on chromatography instruction and delivery of this key technique by non-experts, according to Tony Edge, President of The Chromatographic Society (ChromSoc). Can this trend be reversed?

Gaëlle Spileers from the Separation Science Group in the Department of Organic and Macromolecular Chemistry at Ghent University, Belgium discusses developments in high performance liquid chromatography (HPLC–XRF) for the analysis of brominated flame retardants and other pollutants.

Gaëlle Spileers from the Separation Science Group in the Department of Organic and Macromolecular Chemistry at Ghent University, Belgium discusses developments in high performance liquid chromatography (HPLC–XRF) for the analysis of brominated flame retardants and other pollutants.

Frederic Lynen from the Separation Science Group in the Department of Organic and Macromolecular Chemistry at Ghent University, Belgium discusses why he worked with Gaëlle Spileers to develop a high performance liquid chromatography X-ray fluorescence (HPLC–XRF) technique to analyze brominated flame retardants and other pollutants.

Melissa Dunkle, senior research scientist at Dow Benelux BV, The Netherlands, explores practical aspects of using multidimensional pyrolysis gas chromatography (Pyr-GCxGC) to investigate fluoropolymer degradation.