LCGC Interviews

André Striegel recently published a book called "Macromolecular Separations". In this segment, he highlights the most significant technological advances and changes in macromolecule analysis in the last ten years.

The sliding windows in ion mobility (SWIM) approach leverages predictable correlations between retention time and collision cross-section values to improve confidence in identifying semi-volatile contaminants by GC-IMS-HRMS.

André Striegel examines the major hurdles facing macromolecular separations today and discusses how chromatographers can work to overcome them.

At Pittcon 2026, LCGC International Emerging Leader Award Winner, Bob Pirok, emphasized the importance of incorporating chromatographic expertise into machine learning approaches for successful automated method development.

At analytica 2026, Gauthier Eppe described adding ion mobility–HRMS to GC–HRMS workflows to support analysis of environmental pollutant mixtures.

André Striegel discusses how work in industry, academia, and government has shaped his view of innovation in separation science and practical impact.

At Pittcon 2026, Dal Nogare Award winner André Striegel discusses unresolved chromatography fundamentals and outlines research paths for progress.

Rasmus Bro shows how generative AI extends chemometrics by automating curation, linking analytical data with text knowledge, and improving interpretation.

At Pittcon 2026, Mary Ellen McNally discussed sustainable chromatography, highlighting SFC, low-solvent LC, and greener sample prep to cut waste in industrial labs.

Kevin Schug identifies the key challenges preventing wider uptake of molecular encoding and machine learning tools in everyday analytical laboratory settings.

Kevin Schug examines how models trained on known compounds perform when applied to unseen molecules or transferred to new experimental setups.

Kevin Schug outlines the criteria used to select machine learning methods for analytical problems and how success is defined and evaluated.

Peter Tranchida on the robustness of enantiomeric ratio profiling across food types.

Kevin Schug explores how molecular encoding bridges chemistry and data science to enhance precision and intelligence in analytical measurements.

Peter Tranchida on how cryogenic band compression boosts sensitivity across analytes.

Peter Tranchida explains how cryogenic band compression and GC×GC boost sensitivity while reducing sample preparation demands in complex food analyses.

In this interview recorded at analytica 2026 in Munich, Giorgia Purcaro discusses how GC‑based hyphenated techniques are reshaping the analysis of complex food samples.

Giorgia Purcaro explains how hyphenated GC and GC×GC deliver rich fingerprints, simplify prep, and enable targeted and untargeted food analysis.

At analytica 2026, Gert Desmet of Vrije Universiteit Brussel mulls over the ways these next-generation columns deliver environmental or resource-use benefits over conventional packed beds.

Caroline West highlights how advances in SFC instrumentation are driving greener, more versatile analytical workflows across diverse applications.

Caroline West highlights how advances in SFC instrumentation are driving greener, more versatile analytical workflows across diverse applications.

In the final part of this roundtable discussion focused on the experiences, challenges, and contributions of women in chromatography, LCGC International spoke to Amandaa Brewer, Paola Tiedemann, Chelsea Plummer, and Jennifer Field about the responsibilities we all have to shape a more inclusive future.

At analytica 2026, Gert Desmet of Vrije Universiteit Brussel dicusses the key barriers to routine industrial or clinical adoption of these technologies, and how far away widespread use is.

In the sixth part of this roundtable discussion focused on the experiences, challenges, and contributions of women in chromatography, LCGC International spoke to Amandaa Brewer, Paola Tiedemann, Chelsea Plummer, and Jennifer Field about the skills that can be overlooked for a career in analytical science.

At analytica 2026, Gert Desmet of Vrije Universiteit Brussel compares the main fabrication approaches across micro-pillar arrays, 3D-printed supports, and multi-capillary channel columns, weighing each against factors such as scalability, cost, and the degree of structural control they offer.