April 22nd 2024
In this interview, we asked Hemanth Kumar Chanduluru from the SRM Institute of Science and Technology in Kattankulathur, India, multiple questions regarding sustainability in analytical separation methods.
Rising Stars of Separation Science: Victor U. Weiss
March 9th 2022This month we interview Victor U. Weiss, Assistant Professor at TU Wien, about his focus on the analysis and electrophoretic separation of nanoparticles from organic, inorganic, and biological sources, and the concept behind nES GEMMA.
The Return of the HPLC Conference
February 10th 2022After a pandemic-induced hiatus since the 2019 event in Milan, the HPLC conference is on schedule to return, June 18–23, 2022, in San Diego, California, as an in-person conference. Frantisek (Frank) Svec, the chair of HPLC 2022, shares news about the conference and his excitement about the coming event.
Detecting Environmental PFAS Using Liquid Chromatography–Tandem Mass Spectrometry
January 21st 2022The presence of per- and polyfluoroalkyl substances (PFAS) in products used every day by millions of people is a cause of concern among both consumers and scientists. PFAS found in drinking water and the environment can cause serious health issues in animals and humans. Amanda Belunis, who is a PhD candidate at the University of Maryland in Baltimore County, has been investigating the use of liquid chromatography–tandem mass spectrometry (LC–MS/MS) to detect PFAS from a variety of environmental sources. She spoke with us about methods used to detect PFAS and described a new method that she and her team have developed to enhance PFAS detection.
Rising Stars of Separation Science: Hedvika Raabová
January 14th 2022This month we interview Hedvika Raabová, a graduate student at the Charles University, Faculty of Pharmacy in Hradec Kralove, Czech Republic, about her work using novel micro- and nanofibres during sample preparation, and the concept behind composite micro/nanofibre extractions.
Combating Olive Oil Fraud Using GC–IMS and FGC-Enose
December 1st 2021The adulteration of olive oil is big business. As fraudsters seek to circumvent existing procedures utilising advanced methods, analytical chemists must level up their efforts. LCGC spoke to Michele Suman about novel screening and confirmatory analytical strategies he has investigated to regain the upper hand in the fight against olive oil adulteration.
Rising Stars of Separation Science: Jelle De Vos
November 4th 2021This month we interview Jelle De Vos, Senior Postdoctoral Researcher at the Department of Chemical Engineering, Vrije Universiteit Brussel, Belgium, about his recent work to develop a chromatographic method to characterize nucleocapsid proteins from SARS-CoV-2, and the development of spatial three‑dimensional liquid chromatography (3D-LC) as a separation concept.
Profiling Metabolites in the Beer Matrix
October 13th 2021Stefan A. Pieconzonka and Philippe Schmitt-Kopplin have profiled diverse beer samples by rapid flow-injection analysis (FIA) Fourier transform ion cyclotron mass spectrometry (FTICR–MS). Here, they discuss their approach to this analysis, along with the significance of the Maillard Reaction (MR) in beer quality and analysis.
Three-Dimensional Printing in Ion Mobility and Mass Spectrometry
October 7th 2021Interest in three-dimensional (3D) printing technology is expanding rapidly. What impact can it have in mass spectrometry? Robert Winkler, of the Center for Research and Advanced Studies Irapuato, in Guanajuato, Mexico, is exploring this question. We recently spoke with Prof. Winkler about this work.
Breath Diagnostics Using Chromatography for COVID-19 and Triage Applications
August 4th 2021Professor Paul Thomas from the Centre for Analytical Science at Loughborough University in Leicestershire, UK, discusses the role of a rapid breath diagnostic method for COVID-19 using GC–IMS and the wider impact and realities of field breath testing and analysis through the European Toxi-Triage project.
Advances in Asymmetrical Flow Field-Flow Fractionation (AF4)
June 4th 2021Lars Nilsson from the Department of Food Technology, Engineering and Nutrition, Faculty of Engineering, in Lund, Sweden, discusses the evolution of asymmetrical flow field-flow fractionation (AF4) in bioanalysis for the analysis of therapeutic proteins.
Determining the Sex of Skeletons Hundreds of Year Old with NanoLC–MS/MS
March 16th 2021Rebecca Gowland and her colleagues in the Department of Archaeology at Durham University in the United Kingdom have tested, for the first time, the applicability of a new method of sex estimation utilizing enamel peptides from a sample of permanent and deciduous teeth at different stages of mineralization, from nonadults of unknown sex, including perinates, and using a minimally destructive acid etching procedure and subsequent nano liquid chromatography– tandem mass spectrometry. She spoke to us about her efforts.
Investigating Arson Attacks Using Multidimensional Gas Chromatography (GC×GC)
September 7th 2020A novel chemical fingerprinting method has been developed using multidimensional chromatography and multivariate analysis to investigate potential arson attacks. The Column spoke to Oliver Jones and Jessica Pandohee of RMIT University in Melbourne, Australia, about their research in this field.
Practical Two-Dimensional Liquid Chromatography in Drug Metabolism Studies and Bioanalysis
June 30th 2020Filip Cuyckens from Janssen R&D in Belgium spoke to LCGC Europe about recent innovative approaches he and his team developed to support drug metabolism and pharmacokinetic studies, and the inventive role that two-dimensional liquid chromatography (2D-LC) plays in his laboratory to boost sensitivity, solve recovery issues, and increase overall efficiency.
Three-Dimensional Chiral HPLC Analysis of Extraterrestrial Amino Acids in Carbonaceous Chondrites
January 20th 2020Aogu Furusho from the Graduate School of Pharmaceutical Sciences in Kyushu University, Fukuoka, Japan, spoke to us about his development of a highly selective three-dimensional chiral high performance liquid chromatography (HPLC) system for the determination of extraterrestrial amino acids in carbonaceous chondrites.
Sizing Up Size-Exclusion Chromatography (Part 2)
November 1st 2019In the second part of this interview on size-exclusion chromatography (SEC) André Striegel discusses the benefits of the technique to analyze nanoparticles and quantum dots, the complementary role of hydrodynamic chromatography (HDC), and the future of SEC in two-dimensional liquid chromatography (2D-LC) separations.