Application Notes: General

This application note showcases the SCION 8300 GC with SQ MS's capability to detect limonene in recycled HDPE pellets, emphasizing its high sensitivity and robustness. The method ensures that the recycled pellets, crucial for manufacturing deodorized food packaging, contain limonene concentrations well below the 20ppm threshold, demonstrating the efficacy of the recycling process.

Trifluoroacetic acid (TFA) as an eluent modifier causes baseline ripples, with negative effect on LOD/LOQ. This can be mitigated by adjusting the pump mixer volume

The KNAUER IJM NanoScaler is used to precipitate protein metal carbonate hybrid particles by mixing two inorganic salt solutions in which the protein is dissolved

The KNAUER HPLC Method Converter assists you to modernize the analytical method according to the allowed variations last US and EU Pharmacopeia (USP) chapter 621

Explore SCION Instruments' method for simultaneously analyzing two triazole fungicides, Paclobutrazol and Uniconazole, using HPLC-DAD. This Application Note provides insights into the procedure's effectiveness, highlighting its importance for environmental labs due to health and regulatory reasons.

A preparative system setup is presented for the purification and fractionation of target substances at flow rates up to 800 ml/min with a max. back pressure of up to 100 bar.

Clinical trials can be helpful indicators of where the life sciences industry is headed. Dean Erhardt, BBA, MBA, President & CEO of D2 Solutions, offers his insights regarding the direction of the market and potential growth areas.

Applying Separation Technologies to Overcome Pharmaceutical Analysis Challenges

Monitoring of per- and polyfluoroalkyl substances (PFAS) in air is successfully performed by the US EPA using Thermal Desorption-GC/MS.

Novel Thermal Desorption-GC/MS method for determination of formaldehyde using PFPH, automatically loaded onto Tenax TA adsorbent, as derivatization agent.

GERSTEL TD 3.5+ Thermal Desorber successfully passes method VDA278 system performance test for automobile material emissions increasing sample capacity and throughput.

VOCs collected from air onto a sorbent packed tube are released by thermal desorption and focused for GC-MS determination using the novel cryogen free dynamic focusing

Peptides are versatile molecules that have a wide range of applications in biotechnology, medicine, and research. They can be used as drugs, diagnostics, biomarkers, or tools to study cellular processes. However, peptides also pose unique challenges in terms of analysis and purification due to their complexity, diversity, and sensitivity.

Splitless micro-furnace pyrolysis-GC/MS in conjugation with F-Search MPs libraries enable rapid and accurate identification and quantification of trace Microplastics (MPs).

Discover how to accurately analyze purity and impurities, determine sequences, and more with next-generation technologies from Agilent.

This application note describes a method for the rapid and simultaneous quantitation of benzene, 1,4-dioxane, and formaldehyde in personal care products (PCPs). Nine retail hair and skincare products from the United Kingdom were analyzed, with limits of quantitation (LOQs) for benzene in the low-ng g−1 range and 1,4-dioxane and formaldehyde in the sub- and low- μg g−1 range, respectively. Preliminary results indicate that SIFT-MS holds an 8- to 30-fold throughput advantage when compared to conventional gas chromatography (GC-MS).

Inside the Laboratory is a joint series with LCGC and Spectroscopy, profiling analytical scientists and their research groups at universities all over the world. This series spotlights the current chromatographic and spectroscopic research their groups are conducting, and the importance of their research in analytical chemistry and specific industries. In this “Inside the Laboratory –– Women in Separation Science” special edition PDF, we profile four industry leaders and the impact that their research is having in specific fields such as environmental analysis, forensics, national security, and drug development.

Biozen dSEC-7 accurately resolves AAV serotypes 5, 8 and 9 monomer from aggregates in under 10 minutes with consistent results across different mobile phase conditions.

Photodegradation of plastic products is known to accelerate weathering and the resulting release of chemical additives and particles to the environment, however these processes are complex. Here, eight different plastic consumer products were leached in double-distilled water under exposure to strong ultraviolet (UV) light for ten days, and the chemical composition of the leachates was compared to their respective dark controls. The leachates and plastic particles were investigated with a wide battery of chemical-analytical tools to broadly characterize the underlying processes and possible hazards. These covered (a) metal(loid) analysis, (b) microplastic analysis, (c) analysis of >70 organic target analytes and (d) nontargeted screening of the extracts.

We present a reliable NanoPak-C All Carbon SPE method for extracting and detecting 15 OCPs from small quantities of soil (100 mg) and river water (200 µL) samples.

This application note demonstrates the performance of BioCore SEC columns for determining aggregation and fragmentation associated with antibody-based biotherapeutics.

This application note demonstrates a novel composite technology that enhances reproducibility of solid phase extraction compared to a traditional loose packed format.

This app note outlines SPE extraction of water samples following EPA Draft Method 1634, comparing polymeric HLD SPE cartridges and polymeric HLB SPE cartridges.

This application note demonstrates the use of Thermal Desorption as greener approach for sampling of terpenes in air for workplace exposure or terpene profiling

This application note demonstrates the use of Thermal Desorption as a greener approach for sampling of terpenes in the air for workplace exposure or terpene profiling

GC×GC–TOF MS with thermal modulation used to provide detailed and sensitive characterisation of pyrolysis oil composition to identify possible contaminants.

Analysis of VPH in environmental samples by automated flow-modulated headspace–GC×GC–FID, for robust and efficient sample quantitation.