Application Notes: General

Automated, high-sensitivity analysis of residual fumigants for food safety testing by multi-step enrichment–headspace–trap (MSE–HS–trap) with GC–MS.

Evaluating the effect of storage and packaging on the volatile composition of soft drinks with immersive sorptive extraction & GC×GC–TOF MS.

Analysis of trace per- and polyfluorinated organic vapours in air using cryogen-free thermal desorption and gas chromatography–mass spectrometry.

Microplastics are defined as small plastic particles between 1 µm and 5 mm in size. Due to poor waste management and plastic pollution, they are now documented to be ubiquitous in the environment.1,2 However, pathways of dietary exposure to microplastics are not yet fully understood. The consumption of bottled water has been calculated to increase by 7% annually, with an estimated mean total global consumption of bottled water to be 513 billion liters by 2025. This study demonstrates how the Agilent 8700 Laser Direct Infrared (LDIR) Chemical Imaging System can accurately identify and quantify the presence of microplastics in bottled drinking water. This study also shows the capability of the Agilent Cary 630 FTIR spectrometer to investigate the source of microplastic contamination.

Reports of the omnipresence of microplastics have mainly focused on their presence in the environment, but there is a growing interest in investigating the health impacts of microplastics. Many people would assume that infants' exposure to microplastics would be limited. However, infant formula was found to be a possible exposure pathway. Extracting and isolating microplastics from infant formula can be difficult due to the range of formulations, ingredients, and components, such as fats, proteins, minerals, vitamins, and sugars. This application note demonstrates the importance of quality control in microplastics analysis. The study also shows how the Agilent 8700 Laser Direct Infrared (LDIR) Chemical Imaging System can accurately identify and quantify microplastics in infant formula.

A method to collect and analyse ozone-depleting substances & halogenated greenhouse gases in 100% humidity ambient air with a cryogen-free preconcentration–GC–MS system

This application notes showcases greener HPLC with less solvent using smaller inner diameter columns while maintaining the quality of separation

This application notes showcases greener HPLC with less solvent using smaller inner diameter columns while maintaining the quality of separation

Analyze phthalates 1.4x faster and cut costs by reducing helium consumption 67%.

This application notes showcases greener HPLC with less solvent using columns of shorter length and smaller inner diameter while maintaining the quality of separation

Reduce sample prep time by filtering your water samples in an auto sampler ready Thomson filter vial. These vials help reduce sample prep time and reduced materials needed.

This application note describes the extraction of thirty-one PFAS compounds from human serum using Biotage® ISOLUTE® PLD+ for PFAS prior to UHPLC-MS/MS analysis.

Speed up your sample preparation time by removing syringe filtration or centrifugation steps. Thomson filter vials allow you to filter your ground water samples in autosampler-ready vials.

Replace time consuming and material heavy syringe filtration steps in EPA Method 539 with Thomson filter vials quick 5s filtration in a ready-to-analyze autosampler vial. Thomson filter vials replace the syringe filter, syringe, and auto sampler vials with one filter vial that goes right on your instrument for analysis.

Lipid oxidation generates off-odors in food, edible oils, and fats. DHS or Thermal Extraction-GC-MS/O using Sensory Directed Analysis quickly identifies off-odors.

This comprehensive peer-reviewed set of more than 600 definitions covers topics of interest for the biopharmaceutical and gene therapy subjects of genetics, therapeutics, drug development, clinical medicine, and the analytical science tools used for characterization of drugs. This glossary serves as a helpful reference to both novice and advanced scientists, engineers, and business executives involved with biopharmaceuticals and gene therapy technologies. Online sources of information for topics covered in this guide are also included for additional insights.

In this article, the results of a DIMS air monitoring campaign in Auckland, New Zealand, are described. Real-time SIFT–MS measurements were obtained at three sites over a period of several weeks. At each site, SIFT–MS provided effective on-site analysis to sub-ppbV levels with better than 1-min time resolution.

This study demonstrates high-throughput analysis of BTEX compounds from several matrices (air, water and soil). Detection limits in the single-digit part-per-billion concentration range (by volume) are readily achievable within seconds using SIFT-MS, because sample analysis is achieved without chromatography, pre-concentration, or drying. We also present a calibration approach that enables speciation of ethylbenzene from the xylenes in real time.

This publication reviews VOC pollutant monitoring applications of SIFT-MS in South Korea. SIFT-MS has been applied to emission source characterization, fenceline monitoring, ambient monitoring, pollution mapping, and incident response (including the use of drone-based sampling) for hazardous air pollutants (HAPs), odor nuisance species, and compounds that have high ozone formation potential (OFP) and/or contribute to secondary aerosol (SOA) formation.

Discover the outstanding separation of three plasmid DNA isoforms, linear, open circular and supercoiled in HIC mode using YMC’s BioPro HIC BF column.

Agilent workflow solutions, designed for the food and beverages industry, serve as a comprehensive resource for testing alternative proteins. This compendium provides 15 applications across various domains, such as taste and flavor, nutrition, food quality, and food safety leveraging advanced analytical techniques like ICP-MS, LC/MS, GC/MS, and HPLC.

Headspace-SIFT-MS provides rapid and sensitive analysis of benzene and other contaminants in commercial products. It enables the daily screening of hundreds of samples.

Read about how the University of York used mobile SIFT- MS to experimentally verify that motor vehicle screen wash is a significant unreported source of VOC emissions

SIFT-MS has unique advantages in air quality measurement applications. It enables environmental incidents to be detected and remedied before they escalate.

This application note demonstrates that automated headspace-SIFT-MS analysis has the potential to screen larger sample numbers for the volatile MOH fraction, providing a rapid indication of packaging material contamination. As benzene has also recently been found to be problematic in commercial products, Headspace-SIFT-MS can screen over 220 samples per day for volatile MOSH and MOAH compounds – nearly seven-fold more samples than the routine liquid and gas chromatography method.

Quantitative analysis of volatile nitrosamine impurities in drug products is simplified using SIFT-MS and has a 3X throughput advantage over chromatographic methods.

In this study, Syft Tracer analyzed the same samples in 9 hours that took 5 chromatographic systems 24 hours to complete and still had capacity to spare.