The Application Notebook-02-01-2015

The Application Notebook

The Intrada Amino Acid column has been shown to be a viable solution for the analysis of amino acids by LC–MS without derivatization.

The Application Notebook

Gel filtration chromatography (GFC) is a powerful analytical tool in the separation of antibodies. Traditionally, GFC columns with a dimension of 7.8 mm i.d. × 30 cm are used for analytical purposes.

The Application Notebook

Organochlorine pesticides are among the more notorious organic pollutants. Gaining wide spread attention into the latter part of the 20th century, and ultimately leading to their ban, OCPs remain with us as a legacy contaminant in the environment.

US EPA wastewater method 624 Purgeables was originally published as 40 CFR Part 136 Appendix A in the mid 1980s.

The Application Notebook

Vicinal diketones (VDKs) are naturally produced compounds in the fermentation process. The monitoring of VDK levels is of great importance as the concentration of these compounds can greatly alter the flavor of a beverage.

B vitamins are a group of water soluble vitamins that play an important role in cell metabolism. This group consists of a number of compounds including thiamine (vitamin B1), riboflavin (vitamin B2), niacin and nicotinamide (vitamin B3), and pyridoxine and pyridoxal (vitamin B6).

The Application Notebook
Food & Beverage

February 01, 2015

Lactulose, a semi-synthetic disaccharide, is a useful indicator for heat induced modifications in milk. Lactulose can be derived from lactose by alkaline isomerization or enzymatic transgalactosylation of fructose.

Direct exposure probe (DEP) coupled to the Pegasus HT, time-of-flight mass spectrometer, was used for the identification of synthetic cannabinoids in MTN-series compounds.

The Application Notebook

Mobile phase pH is a powerful tool in methods development, particularly for separation of neutral forms of amines or other organic bases under alkaline conditions.

Photonis has combined two of our superior detection and analysis technologies into a new digital ion beam profiling unit. The new Ion Beam Profiler combines a large microchannel plate (up to 120 mm) in a complete assembly with the Photonis Nocturn, a high-resolution digital CMOS low-light camera which is immune to sudden light damage.

The Application Notebook
Pharma/Drug Discovery

February 01, 2015

Avermectins are a series of 16-membered macrocyclic lactone derivatives that are used extensively in animal and crop protection.

Silica-based cyano stationary phases have historically exhibited poor stability and short column lifetime at pH extremes. This application note details an investigation of the stability of YMC's Cyano-HG (high strength) 10 ?m silica-based stationary phase, which was performed at a customer's request.