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The authors demonstrate the use of multiple-injection affinity capillary electrophoresis (MIACE) and several variations to MIACE to determine binding constants between the glycopeptide antibotics vancomycin, ristocetin, and teicoplanin from Streptomyces orientalis, Nocardia lurida, and Actinoplanes teichomyceticus, respectively, and D-Ala-D-Ala terminus peptides.

Joining us for this discussion are Kevin D. Altria of GlaxoSmithKline R&D; William Ciccone of MicroSolv Technology Corp; and Brian Nunnally of Wyeth.

September marks the beginning of a busy time in the world of analytical chemistry, with several conferences taking place in the span of just a few months.

IgG Aggregation Characterization - Wyatt Apps Note

Scientists from Brigham Young University (Provo, Utah) and Weber State University (Ogden, Utah) used on-column spectroscopic measurements to investigate density gradients in packed capillary supercritical fluid chromatography (SFC) columns operated at the pressure drops used for solvating gas chromatography.

6-amino-n-caproic acid: Easy ANP on a C18 - MicroSolv Apps Note

Simultaneous Analysis of Quercitrin, Isoquercitrin, and Hyperoside - Hitachi Apps Note

5-minute analysis of fat soluble vitamins - Waters Apps Note

A reader response to Incognito's article featured in the May issue of The Column.

LabLogic Systems have been chosen by the Department of Medical Physics and Clinical Engineering at Addenbroke's Hospital in Cambridge, UK to supply the equipment to support the department?s metabolite analysis system for early-phase PET studies.

With this HPLC application, the determination of catecholamines is performed from urine.

E-Z isomer separation by SFC - Thar - Apps Note

BioTek Instruments has appointed Millennium Science as their official distributor in New Zealand. Millennium Science will now be responsible for sales and support of the company?s entire line of microplate-based instrumentation and software in New Zealand and Australia.

Simultaneous Analysis of Quercitrin, Isoquercitrin, and Hyperoside On the Hitachi LaChrom Elite? Liquid Chromatography System - Hitachi Apps Note

UHPLC–MS–MS Analysis of Lactotripeptides in Food and Dietary Supplements R.A.M. van der Hoeven, O.L. Schoten and I.A.L.A. Boogers Advantages of Using Ultra High Tempeature in High Throughput LC and LC–MS L. Pereira, S. Aspey and H. Ritchie News Volatile compounds in wine, a US patent award, floral chemistry and sorting single-walled carbon nanotubes by size, property and chirality are in the news this issue. Market Trends and Analysis Market Profile: Environmental Testing Market Glenn Cudiamat Q&A The Emperor's 'Old' Clothes Dr Francisco Vilaplana from the Polymer Interactions group in the Department of Fibre and Polymer Technology, Royal Institute of Technology in Stockholm, Sweden talks to Felicity Thomas from The Column about a conservation project for historical costumes. Events

Incognito considers the usefulness and scope of the Quality by Design approach to HPLC method development through a question and answer format.

Urine?Diabetic vs. Non-Diabetic Using Statistical Compare - LECO Apps Notes

Protein Deamidation by Cation-Exchange Chromatography - Dionex Apps Note

Joining us for this discussion are Fraser McLeod of Dionex Corporation; Bob McDowall of McDowall Consulting; and Linda Doherty, Dan Holmes, Jeff Louie, and Leon Kopelev of Agilent Technologies, Inc.

The Effect of Water on Low Temperature Heat Transfer Fluid Performance - Paratherm Whitepaper

PerkinElmer (Waltham, Massachusetts) announced that the U.S. Patent & Trademark Office has awarded it a patent titled ?Methods and Systems for Characterizing a Sorbent Tube,? which describes an approach for helping users avoid manual errors in automated thermal desorption (ATD) gas chromatography (GC).

Using solid-phase extraction sorbent followed by LC–MS–MS analysis using HILIC to measure melamine and cyanuric acid in under 3 mins.

The following question and answer were taken from LCGC Europe's "CE Currents" column (1).

It has been announced that Agilent Technologies will pay $1.5 billion, cash, for life sciences consumables and instrumentation supplier, Varian.

One thing all chromatographers know for certain is that, in the words of John Dolan in his April 2006 column, 'It's gonna break.' And when it does, there are a variety of services to choose from in the field of separation science. Our experts explore them here, updating readers on all that is new and innovative in this area.

By now, a reader would have to be living in a log cabin without electricity to be unaware of the acetonitrile shortage currently gripping the chromatography market. The causes, effects, and possible solutions have been documented thoroughly in the pages of LCGC and other industry journals, to the point where the basic facts are common knowledge: the shortage began with (among other factors) the depression of the automobile industry and the consequent reduced production levels. With ACN being a byproduct of this process, its production was reduced as well.

Columnist Michael Balogh looks back on a 1997 LCGC article he wrote, and examines how many technological advances the field of MS has witnessed in the decade since.

New and better software solutions are being created every day in the marketplace, leading to some exciting breakthroughs that promise to make labs and businesses in general more productive.