Obtaining Allicin from Garlic with High-Speed Counter Current Chromatography
February 14th 2025High-speed counter current chromatography (HSCCC), an advanced liquid-liquid chromatography technique employing both a liquid stationary phase and a liquid mobile phase (effectively eliminating irreversible adsorption), was used to harvest allicin from garlic.
Identifying Microplastics in Tap Water with Py-GC/MS
February 12th 2025A pyrolysis gas chromatography-mass spectrometry (Py-GC/MS) methodology has been specifically developed for the identification and quantification of seven polymers commonly found in tap water. The researchers responsible for the approach state that it prioritizes both time and cost efficiency without compromising the thoroughness of marker spectrum detection and confirmation.
The 2025 Lifetime Achievement and Emerging Leader in Chromatography Awards
February 11th 2025Christopher A. Pohl and Katelynn A. Perrault Uptmor are the winners of the 18th annual LCGC Lifetime Achievement and Emerging Leader in Chromatography Awards, respectively. The LCGC Awards honor the work of talented separation scientists at different stages in their career (See Table I, accessible through the QR code at the end of the article). The award winners will be honored during an oral symposium at the Pittcon 2025 conference held March 1-5, in Boston, Massachusetts.
Examining Alkaloid Profiles in Milk with LC-MS
February 10th 2025Research conducted by The Technology Transfer Center of the Edmund Mach Foundation (San Michele all'Adige, Italy) and the University of Udine (Udine, Italy) used liquid chromatography coupled with high-resolution mass spectrometry (LC-MS) to investigate alkaloid transfer from alpine pastures to milk.
Using Chromatography to Explore Fluorescent Bioactive Compounds in the Coelomic Fluid of Earthworms
February 6th 2025A study aiming to identify fluorescent bioactive compounds in the coelomic fluid of earthworms, as well as to investigate their structural and functional characteristics for possible use in biomedical applications, utilized a variety of chromatographic techniques.
Evaluating Dissolved Organic Matter with GPC and Spectroscopy
February 4th 2025Gel permeation chromatography, three-dimensional excitation-emission matrix fluorescence spectroscopy, and UV-visible spectroscopy was utilized to assess road runoff passed through a filter filled with sludge from drinking water treatment plants to evaluate its capacity for removing dissolved organic matter (DOM).
Assessing Metal-Induced Glycation in French Fries with LC-MS/MS
February 3rd 2025A recent study described develops methods for synthesizing and quantifying metal-induced glycation products, particularly in French fries, with phytic acid as a natural chelating agent (NCA). LCGC International spoke to Makan Golizeh, corresponding author of the paper inspired by this research, about the study and the team’s use of liquid chromatography-tandem mass spectrometry (LC–MS/MS) in their research.
Identifying Multidimensional Characteristics of PFAS Using LC-DTIMS-HRMS
January 31st 2025A recent study used a liquid chromatography-drift tube ion mobility spectrometry-high resolution mass spectrometry (LC-DTIMS-HRMS) platform to contribute to characterizations of 175 per-and polyfluoroalkyl substances (PFAS) with authentic standards in a multidimensional manner.
PFAS Dermal Absorption: An Overview of Science and Regulation
January 31st 2025Per- and polyfluoroalkyl substances (PFAS) often make headlines as health agencies worldwide work to regulate their use. While most restrictions focus on PFAS in drinking water, the primary exposure pathway, scientists are increasingly investigating alternative routes, such as dermal absorption from cosmetics, sunscreens, and other everyday products.
Measuring Vitamin D3 in Hen's Egg Yolk with HPLC
January 29th 2025Researchers have developed a method employing high performance liquid chromatography with ultraviolet detection (HPLC-UV) to determine vitamin D3 in food (even in the presence of vitamin D2, and with a specific focus on egg yolk) in a cost-effective and quantitative manner.
PFAS Identified in Smartwatch and Fitness Bands Using LC–MS/MS
January 28th 2025“Forever chemicals” per- and polyfluoroalkyl substances (PFAS) have been found in smartwatch and fitness bands and analyzed using liquid chromatography tandem mass spectrometry (LC–MS/MS) and direct total oxidative precursor (dTOP) assay.
Exploring Severity of Traumatic Brain Injury with DI/LC-MS/MS
January 27th 2025Researchers employed direct infusion/liquid chromatography-tandem mass spectrometry in their exploration of the potential of metabolomics to examine probable primary and secondary brain injury in severe traumatic brain injury.