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In Part 2 of "Conversations with Michael Dong," the LCGC column editor discusses HPLC columns for pharmaceutical analysis and the case for short columns.

Gas chromatography-mass spectrometry (GC–MS) shows scarlet macaw feather scent varies by sex and mate status.

Martina Lioi pairs IP-HILIC and RP to map impurities in fatty acid–linked siRNAs

Gas chromatography-mass spectrometry (GC–MS) reveals bisphenol A and other lasting pollutants in Maricá Lagoon (Brazil) sediments.

This week, Chromatography Online covered automated GC-MS/MS testing for phthalates in oils, chemicals hidden in bioplastic packaging, troubleshooting tips for oligonucleotides and GLP-1 peptides, automated glycan profiling, NIST reference materials, and the experience of being the only woman in the laboratory.

Multidimensional chromatography cuts ion suppression in complex environmental samples by separating salts and coeluting compounds from target analytes.

The panel discusses quantitative peptide analysis, including drug substance vs. drug product complexity, recovery, and methionine oxidation risk.

Gas chromatography–quadrupole time-of-flight mass spectrometry (GC–QTOF MS) screening of dust finds 269 contaminants in homes, offices, and schools.

Click here to access the LCGC International September/October 2026 European PDF in an interactive format.

Gas chromatography-mass spectrometry (GC–MS) reveals citral drives inhaled magnolia oil's attack on breast cancer.

The 2026 Gulf Coast Conference (GCC) will be held at the Moody Gardens Convention Center in Galveston, Texas, from October 12–15.

The panel cover protecting peptide recovery, from mobile-phase pH and diluent buffers to inert column hardware.

Henri B. Kagan and Kenso Soai win 2026 Nobel Prize in Chemistry for explaining molecular handedness

Liquid chromatography–tandem mass spectrometry (LC-MS/MS) and sequencing link fungi to Fusarium and Alternaria toxins in barley.

Liquid chromatography-high resolution mass spectrometry (LC-HRMS) identifies over 700 contaminants and antimicrobial resistance (AMR) risks in Indian hospital wastewater.

HPLC 2026 highlights AI, 2D-LC, new materials, and pharma separations.

Kinjal Bhatt and Ina Varfaj redefine career success around energizing work and personal balance, moving past publications and promotions.

Piotr Alvarez explains how his lab uses 2D-LC to enable MS compatibility with legacy methods and to confirm peak purity through orthogonal separation.

Florian Geistmann succeeded retiring Jürgen Semmler as Shimadzu Europa managing director on October 1.

Liquid chromatography-mass spectrometry (LC-MS) profiling reveals chemical diversity across grapevine varieties.

Liquid chromatography-mass spectrometry (LC-MS) and nuclear magnetic resonance (NMR) link perinatal factors to infant urinary metabolite changes.

This LCGC Blog installment explains how NIST categorizes and certifies reference materials, and why they underpin reliable results in science and medicine.

Comparing manual and automated N-glycan profiling of a trastuzumab biosimilar, researchers found that both workflows detected the same glycan types, but automation gave more reproducible results (mean CV of about 5.7% vs. 7.95%), making it better suited to high-throughput analysis in biopharmaceutical development.

How can analysts resolve impurities that differ by a single mass unit? Experts discuss deamidation, racemization, HRMS, and 2D-LC for GLP-1 peptides.

"LC Troubleshooting" explores why phosphorothioate oligonucleotides (ONs) diastereomers challenge liquid chromatography.

This new high-performance liquid chromatography (HPLC) method reliably measures cholesterol adsorption in artichoke fiber.

The panel walks through confirming peptide identity–from HRMS and LC–MS/MS sequencing to amino acid analysis and D/L-isomer verification.

Malte Hübschen of the University of Duisburg-Essen (Germany) discusses an automated gas chromatography-tandem mass spectrometry (GC-MS/MS) workflow that improves phthalate detection in tricky oils with LCGC International.