All News

In this month's LCGC Blog, Katelynn Perrault describes a new initiative to promote the importance and practice of chemometrics through an active-learning programme that provides hands-on experience with chemometric workflows using real analytical datasets.

Bruker debuts advanced proteomics, metabolomics, and ultra-high-resolution mass spectrometry (MS) platforms at ASMS.

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) reveals widespread PFAS, bisphenols, parabens, and benzophenones in Andalusian household dust.

Thermo Fisher’s three new mass spectrometer platforms, AI-driven software acquisitions, and integrated workflows aim to reduce analytical tradeoffs across complex scientific markets

Researchers studied oxygenated species formation in nitazene analogs via DART-MS to improve forensic drug screening and address the opioid crisis. LCGC International spoke to Emma Hardwick, lead author of the paper that resulted from this work.

Gas chromatography-mass spectrometry (GC-MS) reveals cultivation-driven shifts in volatile organic compound (VOC) profiles of vanilla orchids without loss of compound diversity.

New R tool auto-decodes polyol structures from mass spec data—great for screening complex formulas.New R tool auto-decodes polyol structures from mass spec data—great for screening complex formulas.

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) quantification of deflazacort metabolites in urine and plasma validates the World Anti-Doping Agency's 30 ng/mL detection threshold.

Rapid chromatography-free method enables untargeted detection of food adulterants for quality control.

James P. Grinias from Rowan University, Glassboro, New Jersey, United States, is the winner of the 2026 HTC Innovation Award, which was presented at the Hyphenated Techniques and Separations Technology (HTC-19) conference in Leuven, Belgium, on Friday May 29, 2026. The award is co-sponsored by the HTC conference and LCGC International.

Using two-column chromatography, a 63.6-fold purified cold-active amylase from potato peel waste shows strong starch-processing potential.

Headspace solid-phase microextraction gas chromatography-mass spectrometry (HS-SPME-GC-MS) identified key aroma compounds differentiating peaches and nectarines by flesh type.

Vaughan Langford discusses the application of automated selected ion flow tube mass spectrometry (SIFT-MS) analysis to diverse high-throughput food analysis applications, including sensory-correlated analysis, authentication, and ingredient screening.

The first session at HTC-19 in Leuven on Wednesday 27 May 2026 kicked off with an inspiring tryptch of speakers —Caroline West, Leon Barron, and Jackie Mosely—exploring innovative aspects of modern hyphenated chromatography.

An illuminating session called AI and Modelling on Wednesday 27 May 2026 at HTC-19 in Leven, Belgium focused on automated and computational approaches to LC method development, with five presentations spanning Bayesian optimization, hybrid retention modelling, QSAR-based retention prediction, graph-theoretic peak alignment, and functional data analysis

Bingchuan Wei describes how to cultivate a culture of innovation and calculated risk-taking while operating within the compliance demands of biopharmaceutical drug development.

Researchers used orbital ion trap liquid chromatography-tandem mass spectrometry (LC-MS/MS) to separate and identify proteins in human eye lens fiber cells.

DEAE-cellulose and gel filtration chromatography purify a selective B. stercoris milk-clotting protease.

High-end mass spectroscopy innovation is driven by proteomics, leaving scientists in other fields like drug development, environmental analysis, and metabolomics underserved.

Ionic liquids (ILs) are structurally tunable salts that pose unique analytical challenges.Ionic liquids (ILs) are structurally tunable salts that pose unique analytical challenges. This article reviews how mass spectrometry is used to study IL ion clusters, dissociation pathways, and decomposition products, with a focus on applications in spacecraft propulsion and environmental contamination.

Bingchuan Wei shares practical guidance for early-career scientists seeking to transition into industry drug development across diverse therapeutic modalities.

Discover the latest advances in metabolomics, LC–MS workflows, spectral libraries, and untargeted analysis during this morning session featuring researchers from academia, government, healthcare, and industry.

Join analytical scientists and instrument experts for a dynamic session showcasing the latest innovations in GC–MS instrumentation, high-throughput workflows, untargeted analysis, and trace-level detection technologies.

Join leading researchers and industry experts for an in-depth session on emerging contaminants, PFAS detection, and non-target analysis strategies shaping the future of environmental testing.

Untargeted liquid chromatography-mass spectrometry (LC-MS) and molecular networking reveal seasonal pollutant shifts and emerging contaminants in South Africa’s Nylsvley wetland.

Gas chromatography-mass spectrometry (GC-MS) quantified para-chloroaniline (PCA) formed in root canals, with sodium ascorbate as a final rinse proving most effective.

Bingchuan Wei reflects on how to connect high-level patient and medical goals to the highly technical analytical tools required to meaningfully support ADC drug development decisions.