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The September issue of LCGC International delivers new perspectives in oligonucleotide analysis, robust data statistics, and advanced workflows for complex biologics.

High-quality, well-labeled data is essential. What steps are being taken—or should be taken—to create standardized, shared chromatographic datasets for AI training? Dave Abramowitz of Thermo Fisher Scientific shares his insights.

Australian researchers set out to determine the chemical composition of anabolic–androgenic steroid (AAS) sold there, specifically to determine the presence and purity of active ingredients and evaluate the presence of cutting agents, residues, or heavy metals. Gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS) were among the techniques used in their study.

What role will human expertise have when artificial intelligence (AI) becomes more deeply embedded in chromatography workflows? Dave Abramowitz of Thermo Fisher Scientific shares his thoughts.

Researchers aiming to investigate the value of serum vitamin D3 levels in patients with a history of malignancy and confirmed lung metastases measured serum Vitamin D2 (25-hydroxyergokalciferol) and D3 (25 hydroxycholekalciferol) levels were measured using high-performance liquid chromatography (HPLC).

Dave Abramowitz of Thermo Fisher Scientific on how he sees artificial intelligence (AI)-driven chromatography tools scaling from research labs to regulated pharmaceutical environments, where compliance and validation are critical, in this first part of our video interview series.

LCGC International spoke to Dave Abramowitz, from the unified product management and product ownership team for chromatography and mass spectrometry software at Thermo Fisher Scientific, about the advantages, challenges, and future potential of AI in chromatography, highlighting how scientists can begin adopting AI-driven tools to improve accuracy, efficiency, and discovery.

Researchers from Iraq, Iran, and Italy analyzed 16 polycyclic aromatic hydrocarbons (PAHs) in grilled beef, kebab, and chicken using magnetic solid-phase extraction with gas chromatography-mass spectrometry (MSPE-GC-MS).

Click here to access the LCGC International September 2025 North America PDF in an interactive format.

Click here to access the LCGC International September 2025 Europe PDF in an interactive format.

Researchers quantified urinary cotinine levels in children with asthma, analyzed correlation with asthma severity, and examined the relationship between parental smoking and urinary cotinine levels. Cotinine analysis was conducted using high-performance liquid chromatography (HPLC).

Seton Hall University has received a $10 million estate gift establishing the Thomas Tencza, PhD Endowed Professorship in Chemistry, providing long-term support for advanced research, graduate training, and separation science initiatives in its highly regarded chemistry and biochemistry programs.

A recent study demonstrated how analytical techniques can be used to differentiate between different types of whiskey.

Researchers at Japan’s National Research Institute of Brewing used ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-QTOF-MS) to analyze the metabolome of sake and build predictive models of its sensory characteristics.

Petroleum contamination from leaking underground storage tanks, for example, is a significant concern for both the environment and human health. Thorough characterization of the contamination is required to form appropriate risk assessments and remediation strategies, but until now, the determination of total petroleum hydrocarbons (TPHs) in soil has typically involved a convoluted and labour-intensive process. In this article, the analysis of TPH in environmental media is simplified using flow-modulated GC×GC–FID with quantitation based on pre-defined compound groupings. This approach overcomes the drawbacks of conventional solvent fractionation approaches, by eliminating the need for sample fractionation and automating data processing workflows.

A joint study between York University and the University of Tehran evaluated conventional analytical methods, such as gas chromatography (GC), high-performance liquid chromatography (HPLC), and mass spectrometry (MS), as well as other emerging portable PAH detection technologies in hopes of significantly improving the health and safety of firefighters by reducing their long-term risks of cancer.

Researchers employed reflectance spectrometric analysis to quantify species-specific plumage coloration, and high performance liquid chromatography (HPLC) to elucidate the feather carotenoids of South Asian flameback woodpeckers to assess their pigment chemistries and genomic underpinnings.

This week, LCGC International published a variety of articles on hot topics in separation science. Some of the articles included in this week’s update explore topics such as the metabolic risk in horses, the bioactivities in chili pepper varieties, and a report on the analytical instrument market for Q2 2025. Below, we’ve highlighted some of the most popular articles that were published this week.

A recent paper published in Parasites & Vectors presented a simplified gas chromatography-mass spectrometry-electroantennographic detection (GC-MS-EAD) setup for the detection of the volatile organic compounds (VOCs) emitted by a healthy dog and that elicit antennal responses in P. perniciosus sand flies.

A recent study employed three brands of commercially available ready-to-heat roasted catfish to investigate the off-flavor substances present after reheating, utilizing gas chromatography-electronic nose (GC-E-Nose), GC-ion mobility spectrometry (GC-IMS), and GC-olfactory-mass spectrometry (GC-O-MS )in conjunction with sensory omics.

Analytical instrument makers reported strong Q2 2025 results, driven by sustained demand in the pharmaceutical and chemical industries, with consumables and recurring revenues outpacing instrument sales.

PerkinElmer expands globally with new facilities in the U.K. and China and launches a strategic partnership with Covaris and Hamilton to enhance laboratory solutions and diagnostics worldwide.

Twenty years ago, the fraud at Able Laboratories was uncovered. A chromatography data system (CDS) was at the center of the fraud. What have regulated laboratories learnt since then?

We highlight how chromatography is being used to analyze Irish whiskeys.

Researchers evaluated metabolic abnormalities in six neonatal Noma foals that died shortly after birth, using laboratory tests, pathological examinations, serum amino acid (AA) analyses, genetic analyses, and gas chromatography-mass spectrometry (GC-MS).

The concept of theoretical plates is the key measure of column efficiency in chromatography, linking Nobel Prize–winning theory with practical tools for achieving sharper peaks, better resolution, and reliable separations.

This explainer video highlights why Analytica coming to North America is a big deal in the separation science community.