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Click the title above to open the LCGC Europe August 2019 regular issue, Volume 32, Number 8, in an interactive PDF format.

Click the title above to open the August 2019 issue of the LCGC North America Annual Industry Trends & Directory Issue, Volume 37, Number 8, in an interactive PDF format.

The 2019 LCGC salary and employment survey extracted from calendar years 2018–2019 trends shows a slight increase in average salaries over previous years, and a narrowing of the gender gap in several categories.

To better understand modern sample preparation techniques-such as ultrasound-assisted extraction, microwave-assisted extraction, and pressurized solvent extraction-we should look at the lessons these methods took from Soxhlet extraction.

In LC–MS, the importance of tuning and calibrating the mass spectrometer cannot be overemphasized. There are six main aspects to address.

HILIC has rapidly evolved into a practical technique. For analyzing highly polar compounds, HILIC can be far more straightforward than GC or reversed-phase LC with derivatization, and can lead to a simpler final method with robustness comparable to that of reversed-phase LC.

Several regulatory data integrity guidance documents require that laboratories understand the data life cycle of their processes, but provide only vague definitions of what a data life cycle is. Here is a practical interpretation.

Direct coupling of ion-exchange separations to mass spectrometric (MS) detection is increasingly being used for analyses of molecules ranging from organic acids to proteins. These approaches leverage both the exquisite selectivity of the ion-exchange mode for charge-based separation, and the tremendous power of mass spectrometry for identification of unknowns and trace-level quantitation.

This instalment is the first of a series of four white papers on high performance liquid chromatography (HPLC) modules (pump, autosampler, UV detector, and chromatography data system) to be published in 2019. This instalment provides an overview for analytical-scale HPLC pumps, including their requirements, modern designs, operating principles, trends, and best practices for trouble-free operation.

The 12th Balaton Symposium on High‑Performance Separation Methods will be held 11–13 September 2019 in the Hotel Azúr in Siófok, Hungary.

As I receive reports from clients in Europe and the United States that helium prices are once again increasing, and warnings are being given regarding yet another laboratory-grade helium shortage, my thoughts turn once again to the use of hydrogen as an alternative carrier-gas for gas chromatography.

The Gulf Coast Conference (GCC) is held in Galveston annually. For the past 50+ years, this gathering of international scientists has blazed a trail for analytical needs and innovations for the refining and petrochemical industries.

Data Integrity has become a critical issue in the pharma industry as a result of increased regulatory scrutiny stemming from Data Integrity-related violations. This ebook provides insight on a variety of important topics within this space.

Click the title above to open the LCGC Europe July 2019 regular issue, Volume 32, Number 7, in an interactive PDF format.

As someone who has been associated very closely with poster presentations, I have to say, it is time for a change.

A group of researchers has investigated the impact of combined sewer overflow (CSO) on pharmaceutical and illicit drug use in central London using liquid chromatography–high-resolution mass spectrometry (LC–HRMS).

MilliporeSigma has announced the winners of its Advance Biotech Grant programme in North America.