Data Analysis, Statistics, and Chemometrics

On a fundamental level, equilibrium and diffusion define chemical separations.

Researchers have utilized computational fluid dynamics (CFD) simulations to optimize the design of membrane chromatography devices, enhancing fluid flow uniformity and separation efficiency.

At HPLC 2023, Hyukju Kwon hosted a lecture on the roles LC–MS and artificial intelligence can have in autonomous material discovery.

At HPLC 2023, Kelly Zhang gave a lecture on how machine learning can help further our understanding of the characterization of lipid nanoparticles.

At HPLC 2023, Dr. Joachim Richert held a plenary lecture about what steps need to be taken to reach true laboratory digitalization.

Adjustable polyacrylamide stationary phases developed by researchers enhance separation performance in liquid chromatography, according to a recent publication. The study demonstrates the synthesis of vinyl modified silica and the successful preparation of polyacrylamide modified silica (PAM-SIL) stationary phases, allowing for fine control of separation performance.

How physical and chemical characteristics are related to dirt in the GC system.

In this LCGC Blog, Tony Taylor performs various experiments with ChatGPT to test how useful the AI technology can be in aiding chromatographers' work.

A new publication introduces a groundbreaking automated system for high-throughput mass spectrometry analysis, reshaping the future of biotherapeutic characterization.

Innovative gas chromatography (GC) study combines computer vision and chromatographic fingerprinting to uncover diagnostic signatures in food volatilome.

A researcher has derived an expression for peak width in liquid chromatography with exponential retention and linear program preceded by an isocratic hold, providing valuable insights for enhancing chromatographic separations.

At Pittcon 2023, LCGC spoke with Jim Grinias of Rowan University. This segment is the full-length version of the interview that was conducted at the conference.

The workshop will take place 28–29 June 2023 in Liège, Belgium.

A newly published review reveals insights into the history of capillary electrophoresis, from its development to its current state-of-the-art applications, through a comprehensive bibliometric analysis of publications between 1980 and 2021.

A desorption electrospray ionization mass spectrometry (DESI-MS) method has been developed to effectively analyze historical synthetic dye samples.

A new study tested different solvents and buffer additives for ion mobility spectrometry to test their impact on results.

Scientists have discovered that combining imaging mass spectrometry and microscopy can enhance molecular visualization.

Separation science will be at the core of the artificial intelligence (AI) revolution in science.

Serial coupling of different column types can provide several important benefits to the chromatographer, including fine-tuning selectivity to separate complex mixtures.

On a fundamental level, equilibrium and diffusion define chemical separations. Practical applications of partition coefficients to chromatographic sample preparation illustrate this point.

Understanding the relationship between selectivity and retention is key to realizing excellent gas chromatographic separations.

In this extended special feature to celebrate the 35th anniversary edition of LCGC Europe, leading figures from the separation science community explore contemporary trends in separation science and identify possible future developments.

This instalment of the LCGC Blog investigates fundamental relationships between the structures of molecules and their interaction with different materials, in the context of online supercritical fluid extraction–supercritical fluid chromatography (SFE–SFC).

Paul Bohn, the Arthur J. Schmitt Professor of Chemical and Biomolecular Engineering at the University of Notre Dame, is the 2022 recipient of the Society for Electroanalytical Chemistry (SEAC) Charles N. Reilley Award.

Examples from food science illustrate the usefulness of chemometrics techniques like pattern recognition, regression, and classification.