
Application Notes: General


Extraction of Novel Synthetic 2-Benzylbenzimidazole Opioid Compounds "Nitazenes" (Dec 2022)
This application note introduces a simple targeted extraction method for the analysis of nine nitazene compounds from urine and blood using the Clean Screen® DAU column.



The primary nucleosides encompass a broad array of biological functions associated with RNA, particularly after configuration into multidimensional conformations.

The nutrition profile of food is critical for assessing its quality. In this poster the amino acids in soy flour were hydrolyzed using a Discover Prep microwave system.

Plant-based proteins are becoming a mainstay to grocery stores, restaurants, and retailers. Amino acids in vegan cream cheese are herein hydrolyzed and analyzed.

In this app note, we perform amino acid hydrolysis of proteins to identify and quantify each amino acid utilizing a safe and rapid amino acid hydrolysis protocol.

Protein analysis plays a large role in the production of foods, pet foods, and even pharmaceutical medicines. But first, the amino acids in the protein must be broken down.

Peptide therapeutics are held to high regulatory standards. Discover Prep was used to hydrolyze the amino acids of a peptide in only 15 minutes, instead of 24 hours.

In this study, SPME Arrow sample preparation was tested for the analysis of furan and alkylfurans in baby formula and coffee samples.

Classical protocol of amino acid hydrolysis needs up to 24 h of reaction time. Using the Discover Prep, the same level of acid and base hydrolysis was achieved in minutes.

This application note describes a 2D-LC workflow for Protein A purification of mAbs, followed by online reduction and MS analysis of mAb subunits.

The determination of boiling range distribution of middle distillates and lubricating base oils by GC, with initial IBP of 100°C and FBP of below 750°C.

A separation of parabens is performed on a HALO 90 Å LPH-C18 column under low pH (pH 1) and high temperature conditions compared to a standard C18 SPP column.

A low pH compatible, 90 Å, superficially porous particle C18 phase is introduced as an addition to the chromatographer’s toolbox.

The natural products of the cannabis plant can number up to 100, but the scientific community is concerned with a smaller portion of around 10 to 20 compounds.

A low pH compatible, 90 Å, superficially porous particle C18 phase is introduced as an addition to the chromatographer’s toolbox.

A HALO® LPH-C18 column is used to separate a mixture of 18 cannabinoids, showing fast results and high resolution within critical pairs.

SEC-MALS quantifies biophysical attributes of mRNA, including molar mass, percent aggregates, Rg, and Rh, and how they are affected by formulation and storage.

This app note outlines a highly efficient method for the simultaneous analysis of free and sulfated steroids from urine, plasma, and blood utilizing SPE and LC-MS/MS.

In this study, SPME Arrow sample preparation was tested for the analysis of furan and alkylfurans in baby formula and coffee samples.

Learn the importance of light scattering detection to determine the true molecular weight distribution of a poly(glutamic acid)-based copolymer for drug-delivery.






FAME and cis/trans FAME composition of three omega-3 supplements have been analyzed using two diferent columns, a 100% polyethylene glycol and a 100% biscyanopropyl.

