
Application Notes: General



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The primary nucleosides encompass a broad array of biological functions associated with RNA, particularly after configuration into multidimensional conformations.

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The nutrition profile of food is critical for assessing its quality. In this poster the amino acids in soy flour were hydrolyzed using a Discover Prep microwave system.

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Plant-based proteins are becoming a mainstay to grocery stores, restaurants, and retailers. Amino acids in vegan cream cheese are herein hydrolyzed and analyzed.

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In this app note, we perform amino acid hydrolysis of proteins to identify and quantify each amino acid utilizing a safe and rapid amino acid hydrolysis protocol.

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Protein analysis plays a large role in the production of foods, pet foods, and even pharmaceutical medicines. But first, the amino acids in the protein must be broken down.

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Peptide therapeutics are held to high regulatory standards. Discover Prep was used to hydrolyze the amino acids of a peptide in only 15 minutes, instead of 24 hours.

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In this study, SPME Arrow sample preparation was tested for the analysis of furan and alkylfurans in baby formula and coffee samples.

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Classical protocol of amino acid hydrolysis needs up to 24 h of reaction time. Using the Discover Prep, the same level of acid and base hydrolysis was achieved in minutes.

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This application note describes a 2D-LC workflow for Protein A purification of mAbs, followed by online reduction and MS analysis of mAb subunits.

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The determination of boiling range distribution of middle distillates and lubricating base oils by GC, with initial IBP of 100°C and FBP of below 750°C.

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A separation of parabens is performed on a HALO 90 Å LPH-C18 column under low pH (pH 1) and high temperature conditions compared to a standard C18 SPP column.

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A low pH compatible, 90 Å, superficially porous particle C18 phase is introduced as an addition to the chromatographer’s toolbox.

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The natural products of the cannabis plant can number up to 100, but the scientific community is concerned with a smaller portion of around 10 to 20 compounds.

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A low pH compatible, 90 Å, superficially porous particle C18 phase is introduced as an addition to the chromatographer’s toolbox.

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A HALO® LPH-C18 column is used to separate a mixture of 18 cannabinoids, showing fast results and high resolution within critical pairs.

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SEC-MALS quantifies biophysical attributes of mRNA, including molar mass, percent aggregates, Rg, and Rh, and how they are affected by formulation and storage.

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This app note outlines a highly efficient method for the simultaneous analysis of free and sulfated steroids from urine, plasma, and blood utilizing SPE and LC-MS/MS.

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In this study, SPME Arrow sample preparation was tested for the analysis of furan and alkylfurans in baby formula and coffee samples.

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Learn the importance of light scattering detection to determine the true molecular weight distribution of a poly(glutamic acid)-based copolymer for drug-delivery.




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FAME and cis/trans FAME composition of three omega-3 supplements have been analyzed using two diferent columns, a 100% polyethylene glycol and a 100% biscyanopropyl.


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Dioxins refer to polychlorinated dibenzo-p-dioxins and related compounds polychlorinated dibenzofurans. These two groups of compounds are among the most toxic chemicals.

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GC-TQMS of pesticides is a routine application. The SCION 8900 TQMS with the 8500 GC can perform rapid multiplex screening of pesticides without losing sensitivity.
