Application Notes: General

Accelerate deconvolution of complex MS samples with software that generates an extensive, unbiased, relevant list of structures and component identifiers for your data.

This application note demonstrates a streamlined HPLC method scouting workflow for the analysis of esomeprazole and related degradation products.

A YMC-Triart C18 and a YMC-Triart SIL column were used in RP and NP mode, respectively, for the analysis of four different phosphoramidites.

The recently introduced 1 mm YMC-Triart C18 UHPLC column was used for the high sensitivity LC–MS screening of six antineoplastic drugs.

A YMC-Triart C18 and a YMC-Triart SIL column were used in RP and NP mode, respectively, for the analysis of four different phosphoramidites.

Mipomersen was analyzed by LC–HRMS using a biocompatible YMC-Triart C8 metal-free column, ensuring symmetric peaks, high sensitivity, and no carryover effects.

The separation of three cell-penetrating peptides (CPPs) was performed using a YMC-Triart C18 UHPLC column, providing sharp peaks for a fast analysis in under 4 min.

Twenty-eight PFAS in human serum were analyzed using a YMC-Triart C18 column. An automated SPE system was coupled to an online SPE column-switching LC–MS/MS method.

Four hydrophilic dipeptides were separated with excellent resolution using a YMC-Triart SIL column. Even structurally similar dipeptides were separated in under 4 min.

The analysis of FMOC-derivatized glyphosate and AMPA in water samples was performed using a YMC-Triart C18 UHPLC column at an elevated pH of 9.5.

Methods migration from updating analytical equipment can be a time consuming task. This paper shows many examples of method compatibility and analytical equivalency.

LC–MS workflow for accurate quantification/detection of individual host cell proteins, from sample preparation to the reporting of values of process-related impurities.

Efficient and accurate HPLC analysis of lamotrigine in compliance with USP

USP-compliant assay analysis of hydrocortisone using a PerkinElmer LC 300 HPLC System

Efficient and compliant HPLC analysis of pregabalin

Determination of four complex carbohydrates utilizing a PerkinElmer LC 300 HPLC System, a hydrophilic interaction chromatography (HILIC) technique

HPLC method for saccharide content determination via method CRA SACCH.03 through the analysis of nine commercially available high fructose corn syrups

A review of considerations when optimizing high-throughput methods and achieving fast analyses on Avantor® ACE® HTP-MS columns with examples of key LC–MS separations.

Determination of 16 common cannabinoids utilizing a PerkinElmer LC 300 HPLC System

A robust and sensitive HPLC method with multi-wavelength UV–vis detector for the analysis of 2-phenoxyethanol and seven parabens in commercially available PCPs

USP-compliant method for determination of six isoflavone compounds in dietary supplement capsules with the PerkinElmer LC 300 UHPLC System with PDA detector

A rapid and simple LC method for the analysis of six common VOC metabolites in urine for monitoring occupational exposure to VOCs

This application notes introduces an SPE LC–MS/MS methodology using the Microlute™ CP SCX SPE 96-well microplate for the determination of 12 opioids from human urine.

LPGC–MS is a technique that uses the MS vacuum system, along with a specially designed column setup, to lower pressure inside the entire column, speeding up analysis.

This application note describes how human milk oligosaccharides (HMO) can be analyzed by HPTLC during different production steps (fermentation and finished products).

This application note outlines the fractionation of hydrocarbons into aliphatic and aromatic fractions using UCT’s new silver-phase EPH fractionation cartridges.

 In this application note we demonstrate the excellent performance of Sapiens-624MS columns for the analysis of e-liquids based on ISO 20714.