Application Notes: General

This application compendium demonstrates the utility of a complete suite of ion-exchange columns for charge variant analysis to characterize biotherapeutic proteins.

Discover reliable, accurate analyses across biopharma, including the determination of CQAs, metabolomics, oligos, and more in this application compendium.

This application demonstrates excellent performance in method development for the analysis of raw materials for oligonucleotide synthesis using a biocompatible UHPLC.

This application note describes the drug-to-antibody determination of brentuximab vedotin using a ternary gradient with isopropanol as third channel organic modifier.

This application compendium demonstrates the power of specialty affinity chromatography columns for the isolation and quantitation of monoclonal antibodies.

Explore high-resolution peptide separations in this application compendium that use superficially porous and sub-2 µm reversed-phase columns at HPLC and UHPLC pressure.

Learn about a high-quality peptide separation, which is crucial for primary structure and PTM analysis of mAbs, using a biocompatible UHPLC in this application note.

This application compendium shows everything you need for N-glycan analysis—including easy sample prep kits, labeled and unlabeled glycan standards, enzymes, and columns.

This study demonstrates how to increase sample throughput for glycan characterization workflows using the Agilent AssayMAP Bravo liquid handling platform.

Peptide-mapping analysis shows excellent performance and high method compatibility compared to the Agilent 1290 Infinity II LC System.

This paper describes the requirements for electronic records and electronic signatures for regulated pharmaceutical organizations.

The 1290 Infinity II Bio LC including High-Speed Pump, with its iron‑free flow path, is optimally suited for the conditions used in biochromatography.

The Agilent Bio-Monolith rProtein A (recombinant protein A) analytical column is the latest addition to the Bio-Monolith and affinity chromatography family.

Analysis of antibody drug conjugates using hydrophobic interaction chromatography with the Agilent 1290 Infinity II Bio LC System

Superior resolution in size exclusion chromatography (SEC) protein separation made possible by the Agilent 1290 Infinity II Bio LC System.

The Agilent 1290 Infinity II Bio LC System is the new platform for UV and MS-based primary structure and PTMs analysis of mAbs.

Versatile and efficient direct inject approach to the analysis of 17 PFAS compounds in drinking and surface water samples utilizing PerkinElmer QSight® 420 LC–MS/MS

This application note demonstrates evolved gas analysis (EGA) and multi-step pyrolysis (MSP) with GC–MS on a high-tech waterproof breathable textile.

Accurate detection of halo acetic acids is paramount for the prevention of over oxidation, while still managing enough water sanitation to eliminate water-borne pathogens.

A simple and sensitive method for rapid determination of PFOA and PFOS in water samples by direct Injection UHPLC–MS/MS

This application note describes multi-attribute analysis of monoclonal antibodies. The analyzer combines multidimensional chromatographic multimethod analysis options.