
Application Notes: General


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Identification of impurities in hydrogen fuel supplies was demonstrated using an on-line thermal desorption–GC–MS system, which complied with various standard methods.

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We examined FlexFire columns and their analytical conditions using the synthesized miRNA samples. For this study, we applied inert UHPLC columns to prevent sample loss.


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This application details how the FlexFire mAb-RP column allows for accurate analysis of a wide range of molecular sizes.



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Identification of polyphenolic catechin compounds for health and industrial quantification and quality control of tea products

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Large viral vectors are characterized rapidly using dynamic light scattering and in-depth by multi-angle light scattering in combination with field-flow fractionation.

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This application note describes two approaches for achieving robust, multiresidue pesticide analysis in 10 minutes by GC/MS/MS, while maintaining sufficient chromatographic resolution for the analysis of over 200 pesticides in spinach; a challenging high chlorophyll, fresh matrix.

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Gas chromatography/mass spectrometry (GC/MS) is integral to the analysis of semivolatile organic compounds (SVOCs) in environmental matrices. Recent pressure on the helium (He) supply has required organizations to actively investigate hydrogen (H2 ) carrier gas, but most GC/MS analyses have reduced sensitivity and hydrogenation or dechlorination in the sources. The Agilent HydroInert source retains the ability to analyze a wide calibration range (0.1 to 100 µg/mL) and meet the U.S. Environmental Protection Agency (EPA) method 8270 calibration criteria when using H2 carrier gas.

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This application note shows a micro-flow LC–MS method developed on the Thermo Scientific Vanquish Neo UHPLC system is suitable for high-throughput proteomic analyses of large sample cohorts.

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This application note shows a micro-flow LC–MS method developed on the Thermo Scientific Vanquish Neo UHPLC system is suitable for high-throughput proteomic analyses of large sample cohorts.

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This application note reveals the Thermo Scientific Vanquish Neo UHPLC system offers maximal MS utilization for direct injection workflows and versatility to separate peptides at low flow rates.

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This application note reveals the Thermo Scientific Vanquish Neo UHPLC system offers maximal MS utilization for direct injection workflows and versatility to separate peptides at low flow rates.

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This bibliography is a guide to the scope of Vanquish HPLC and UHPLC usage in literature. Publications have been categorized based on either target analyte or field of application.

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This compendium features proven techniques to help tackle common instrument challenges faced during method transfers to obtain consistent results and sustain regulatory compliance.


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This poster demonstrates an MRM-based multiple-residue LC/MS method for forensic drug quantitation using the new optimizer software on the new Agilent 6475 LC/TQ resulting in several improvements on the new acquisition software

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The active progestin enantiomer levonorgestrel can reliably be separated from the inactive dextronorgestrel using YMC’s immobilised Chiral Art Cellulose-SC column.

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Quality attributes of Adeno-Associated Virus (AAV) vectors are achieved with multi-angle light scattering coupled to separation methods and high-throughput dynamic light scattering.

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mAb and ADC aggregate analysis by SEC is introduced. Separation was improved by suppressing secondary interactions using high concentrations of corrosive salts.

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This application note demonstrates the suitability of automated QuEChERS extract clean-up for pesticide analysis in cereals through micro-SPE and online injection.

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The determination of trace organic acids and inorganic anions in boric acid-treated power plant waters using an automated reagent-free IC system is demonstrated.

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This application note demonstrates the seamless method transfer from research and development to QC enabled by the end-to-end MAM 2.0 workflow.

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Learn how machine learning and artificial intelligence enable new capabilities in proteomics data processing to increase throughput and depth of coverage.

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