Application Notes: General

LC–MS workflow for accurate quantification/detection of individual host cell proteins, from sample preparation to the reporting of values of process-related impurities.

Efficient and accurate HPLC analysis of lamotrigine in compliance with USP

USP-compliant assay analysis of hydrocortisone using a PerkinElmer LC 300 HPLC System

Efficient and compliant HPLC analysis of pregabalin

Determination of four complex carbohydrates utilizing a PerkinElmer LC 300 HPLC System, a hydrophilic interaction chromatography (HILIC) technique

HPLC method for saccharide content determination via method CRA SACCH.03 through the analysis of nine commercially available high fructose corn syrups

A review of considerations when optimizing high-throughput methods and achieving fast analyses on Avantor® ACE® HTP-MS columns with examples of key LC–MS separations.

Determination of 16 common cannabinoids utilizing a PerkinElmer LC 300 HPLC System

USP-compliant method for determination of six isoflavone compounds in dietary supplement capsules with the PerkinElmer LC 300 UHPLC System with PDA detector

A rapid and simple LC method for the analysis of six common VOC metabolites in urine for monitoring occupational exposure to VOCs

This application notes introduces an SPE LC–MS/MS methodology using the Microlute™ CP SCX SPE 96-well microplate for the determination of 12 opioids from human urine.

LPGC–MS is a technique that uses the MS vacuum system, along with a specially designed column setup, to lower pressure inside the entire column, speeding up analysis.

This application note describes how human milk oligosaccharides (HMO) can be analyzed by HPTLC during different production steps (fermentation and finished products).

This application note outlines the fractionation of hydrocarbons into aliphatic and aromatic fractions using UCT’s new silver-phase EPH fractionation cartridges.

 In this application note we demonstrate the excellent performance of Sapiens-624MS columns for the analysis of e-liquids based on ISO 20714.

A robust and sensitive HPLC method with multi-wavelength UV–vis detector for the analysis of 2-phenoxyethanol and seven parabens in commercially available PCPs .

This application note demonstrates rapid peptide desalting prior to LC-MS analysis in Proteomics research using different micropipette SPE StageTips packed with CDS Analytical’s Empore SPE membranes.

Critical quality attributes of lentivirus vector products can be assessed by centrifugal field-flow fractionation coupled to multi-angle light scattering (CF3-MALS).

This application note demonstrates a sample preparation procedure for using the Empore C18 SPE cartridge for the extraction of the THC metabolite, THC-COOH, from urine samples.

Accurate detection of HAAs is paramount for the prevention of over oxidation, while still managing enough water sanitation to eliminate water-borne pathogens.

Chemically resistant resin bed allows for a wide base of mobile-phase choices with excellent anion separation.        

Contamination of drinking water and food sources is of great concern. Isolation and quantification of the various arsenic states are identified.

Isolation of six common allergens by the utilization of reversed-phase HPLC using an alkaline eluent

Chromium can pose as a beneficial element or a poison, therefore it is imperative to identify contaminated waters, especially drinking water.          

Synthesized 40-mer miRNA has been analyzed using both a conventional column and new types of UHPLC columns.

The fight against cancer employs many tools. Paclitaxel, a compound found in the bark of the Pacific yew tree, is one that that has been found to make a big difference.